Homo sapiens (human): 8324
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Entry
8324 CDS
T01001
Symbol
FZD7, FzE3
Name
(RefSeq) frizzled class receptor 7
KO
K02432
frizzled 1/7
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04916
Melanogenesis
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N01427
WNT5A-ROR signaling pathway
N01440
Wnt signaling modulation, LGR/RSPO
N01441
Wnt signaling modulation, SOST/LRP4
Disease
H00031
Breast cancer
H00048
Hepatocellular carcinoma
Drug target
Vantictumab:
D10410
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8324 (FZD7)
04390 Hippo signaling pathway
8324 (FZD7)
04150 mTOR signaling pathway
8324 (FZD7)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
8324 (FZD7)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
8324 (FZD7)
05205 Proteoglycans in cancer
8324 (FZD7)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
8324 (FZD7)
05226 Gastric cancer
8324 (FZD7)
05217 Basal cell carcinoma
8324 (FZD7)
05224 Breast cancer
8324 (FZD7)
09172 Infectious disease: viral
05165 Human papillomavirus infection
8324 (FZD7)
09164 Neurodegenerative disease
05010 Alzheimer disease
8324 (FZD7)
05022 Pathways of neurodegeneration - multiple diseases
8324 (FZD7)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
8324 (FZD7)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
8324 (FZD7)
G protein-coupled receptors [BR:
hsa04030
]
Frizzled / Smoothened family
8324 (FZD7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Frizzled
Fz
Dicty_CAR
Motif
Other DBs
NCBI-GeneID:
8324
NCBI-ProteinID:
NP_003498
OMIM:
603410
HGNC:
4045
Ensembl:
ENSG00000155760
UniProt:
O75084
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:202033855..202038441
Genome browser
AA seq
574 aa
AA seq
DB search
MRDPGAAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDI
AYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPC
RSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYP
TAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRAN
GLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVA
VAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLT
WFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDA
LRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTV
PATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIV
GITTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgcgggaccccggcgcggccgctccgctttcgtccctgggcctctgtgccctggtgctg
gcgctgctgggcgcactgtccgcgggcgccggggcgcagccgtaccacggagagaagggc
atctccgtgccggaccacggcttctgccagcccatctccatcccgctgtgcacggacatc
gcctacaaccagaccatcctgcccaacctgctgggccacacgaaccaagaggacgcgggc
ctcgaggtgcaccagttctacccgctggtgaaggtgcagtgttctcccgaactccgcttt
ttcttatgctccatgtatgcgcccgtgtgcaccgtgctcgatcaggccatcccgccgtgt
cgttctctgtgcgagcgcgcccgccagggctgcgaggcgctcatgaacaagttcggcttc
cagtggcccgagcggctgcgctgcgagaacttcccggtgcacggtgcgggcgagatctgc
gtgggccagaacacgtcggacggctccgggggcccaggcggcggccccactgcctaccct
accgcgccctacctgccggacctgcccttcaccgcgctgcccccgggggcctcagatggc
agggggcgtcccgccttccccttctcatgcccccgtcagctcaaggtgcccccgtacctg
ggctaccgcttcctgggtgagcgcgattgtggcgccccgtgcgaaccgggccgtgccaac
ggcctgatgtactttaaggaggaggagaggcgcttcgcccgcctctgggtgggcgtgtgg
tccgtgctgtgctgcgcctcgacgctctttaccgttctcacctacctggtggacatgcgg
cgcttcagctacccagagcggcccatcatcttcctgtcgggctgctacttcatggtggcc
gtggcgcacgtggccggcttccttctagaggaccgcgccgtgtgcgtggagcgcttctcg
gacgatggctaccgcacggtggcgcagggcaccaagaaggagggctgcaccatcctcttc
atggtgctctacttcttcggcatggccagctccatctggtgggtcattctgtctctcact
tggttcctggcggccggcatgaagtggggccacgaggccatcgaggccaactcgcagtac
ttccacctggccgcgtgggccgtgcccgccgtcaagaccatcactatcctggccatgggc
caggtagacggggacctgctgagcggggtgtgctacgttggcctctccagtgtggacgcg
ctgcggggcttcgtgctggcgcctctgttcgtctacctcttcataggcacgtccttcttg
ctggccggcttcgtgtccctcttccgtatccgcaccatcatgaaacacgacggcaccaag
accgagaagctggagaagctcatggtgcgcatcggcgtcttcagcgtgctctacacagtg
cccgccaccatcgtcctggcctgctacttctacgagcaggccttccgcgagcactgggag
cgcacctggctcctgcagacgtgcaagagctatgccgtgccctgcccgcccggccacttc
ccgcccatgagccccgacttcaccgtcttcatgatcaagtacctgatgaccatgatcgtc
ggcatcaccactggcttctggatctggtcgggcaagaccctgcagtcgtggcgccgcttc
taccacagacttagccacagcagcaagggggagactgcggtatga
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