Homo sapiens (human): 9294
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Entry
9294 CDS
T01001
Symbol
S1PR2, AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2
Name
(RefSeq) sphingosine-1-phosphate receptor 2
KO
K04292
sphingosine 1-phosphate receptor 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04071
Sphingolipid signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
Disease
H00605
Deafness, autosomal recessive
Drug target
Amiselimod (
DG02399
):
D10904
D10905
Ozanimod (
DG02827
):
D10967
<JP/US>
D10968
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04071 Sphingolipid signaling pathway
9294 (S1PR2)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
9294 (S1PR2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
9294 (S1PR2)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Lipid
Sphingolipid
9294 (S1PR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
Motif
Other DBs
NCBI-GeneID:
9294
NCBI-ProteinID:
NP_004221
OMIM:
605111
HGNC:
3169
Ensembl:
ENSG00000267534
UniProt:
O95136
Structure
PDB
PDBj
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All DBs
Position
19:complement(10221433..10231331)
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AA seq
353 aa
AA seq
DB search
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
NT seq
1062 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcttgtactcggagtacctgaaccccaacaaggtccaggaacactataattat
accaaggagacgctggaaacgcaggagacgacctcccgccaggtggcctcggccttcatc
gtcatcctctgttgcgccattgtggtggaaaaccttctggtgctcattgcggtggcccga
aacagcaagttccactcggcaatgtacctgtttctgggcaacctggccgcctccgatcta
ctggcaggcgtggccttcgtagccaataccttgctctctggctctgtcacgctgaggctg
acgcctgtgcagtggtttgcccgggagggctctgccttcatcacgctctcggcctctgtc
ttcagcctcctggccatcgccattgagcgccacgtggccattgccaaggtcaagctgtat
ggcagcgacaagagctgccgcatgcttctgctcatcggggcctcgtggctcatctcgctg
gtcctcggtggcctgcccatccttggctggaactgcctgggccacctcgaggcctgctcc
actgtcctgcctctctacgccaagcattatgtgctgtgcgtggtgaccatcttctccatc
atcctgttggccatcgtggccctgtacgtgcgcatctactgcgtggtccgctcaagccac
gctgacatggccgccccgcagacgctagccctgctcaagacggtcaccatcgtgctaggc
gtctttatcgtctgctggctgcccgccttcagcatcctccttctggactatgcctgtccc
gtccactcctgcccgatcctctacaaagcccactactttttcgccgtctccaccctgaat
tccctgctcaaccccgtcatctacacgtggcgcagccgggacctgcggcgggaggtgctt
cggccgctgcagtgctggaggccgggggtgggggtgcaaggacggaggcggggcgggacc
ccgggccaccacctcctgccactccgcagctccagctccctggagaggggcatgcacatg
cccacgtcacccacgtttctggagggcaacacggtggtctga
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