KEGG   Xenopus laevis (African clawed frog): 379497
Entry
379497            CDS       T01010                                 
Symbol
hsd11b1.L, hsd11, hsd11b, hsd11b1
Name
(RefSeq) hydroxysteroid (11-beta) dehydrogenase 1 L homeolog
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00140  Steroid hormone biosynthesis
xla00980  Metabolism of xenobiotics by cytochrome P450
xla01100  Metabolic pathways
Module
xla_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    379497 (hsd11b1.L)
Enzymes [BR:xla01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     379497 (hsd11b1.L)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Shikimate_DH RecA DUF1776 THF_DHG_CYH_C NAD_binding_2 2-Hacid_dh_C KH-I_KHDC4-BBP
Other DBs
NCBI-GeneID: 379497
NCBI-ProteinID: NP_001079807
Xenbase: XB-GENE-960494
UniProt: Q7SYR9 A0A974DMV5
LinkDB
Position
2L:complement(52284039..52291132)
AA seq 294 aa
MAVLKVLVAFAGIFLAVYFYSAGDVFEPAMLKGKRVIVTGASSGIGEQMAYHLAKMGSHI
LITARTEEKLKKVVAQCTQLGAASAHYIAGSMDNLTFAKQVVHKAENLFGALDMLILNHI
GHTYFGYFDGNVDHVRGLLEINVLSYATMTVAALPMLKKSNGNIVVVSSIAGKIGLPLSV
PYSTTKFALDGFFSSLRMEFIQQNTNVSITLCVISYIDTDSAVKTVSGVIQQPAAPKEEC
ALEIIKGGSLRKREVYYQYHATKIPLLLRDWAPELLQSLLLKNYNMDNFQRREV
NT seq 885 nt   +upstreamnt  +downstreamnt
atggctgtgctcaaagtgcttgttgcttttgctggaatctttctcgctgtttacttttat
tcagcaggggatgtctttgaaccggctatgcttaagggcaagagagtaatagtcacagga
gcaagttcaggaattggagagcaaatggcatatcatctggccaagatggggtctcatatt
ctcataacagcaaggacagaagagaaacttaagaaggtagttgcgcagtgtacacagctg
ggagctgcttctgctcattacattgccggcagcatggacaatttgacatttgcaaagcaa
gtagtgcacaaagctgagaacttatttggtgcgttggacatgcttatcttaaatcacatt
ggtcacacatactttggttactttgatggcaatgtggatcatgtaagaggtctattagag
atcaatgtcctgagttacgctaccatgacagtagctgcacttccgatgctaaaaaaaagc
aacgggaatattgtggttgtctcatcaattgcaggtaaaattggactccctctatctgtg
ccatactctactaccaaatttgcactggatggatttttcagctcattgcgaatggagttt
atccagcaaaacactaatgtttctattacactatgcgtcatcagctatattgacacagat
agtgctgtaaaaactgtgtcaggtgtaatccagcaaccagcagctcctaaagaagagtgc
gcactcgaaattataaaaggtggatcactccgaaaaagggaagtttactatcaatatcat
gccaccaagattccactcctgctcagagactgggcaccagaattattacagtctcttctc
cttaagaattataacatggacaattttcagaggagagaagtttag

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