AU556110B2 - 9-deoxy-9a-methylene isoesters of pg12 - Google Patents

9-deoxy-9a-methylene isoesters of pg12

Info

Publication number
AU556110B2
AU556110B2 AU14048/83A AU1404883A AU556110B2 AU 556110 B2 AU556110 B2 AU 556110B2 AU 14048/83 A AU14048/83 A AU 14048/83A AU 1404883 A AU1404883 A AU 1404883A AU 556110 B2 AU556110 B2 AU 556110B2
Authority
AU
Australia
Prior art keywords
isoesters
deoxy
methylene
methylene isoesters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU14048/83A
Other versions
AU1404883A (en
Inventor
Roberto Ceserani
Franco Faustini
William Fava
Angelo Fumagalli
Carmelo A. Gandolfi
Carlo Passarotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT7819616A priority Critical patent/IT7819616A0/en
Priority to CS804928A priority patent/CS215150B2/en
Priority to CS79513A priority patent/CS215149B2/en
Priority to ZA79268A priority patent/ZA79268B/en
Priority to KR7900219A priority patent/KR840000948B1/en
Priority to HU79EA191A priority patent/HU182726B/en
Priority to BE193094A priority patent/BE873731A/en
Priority to SU802930648A priority patent/SU1360582A3/en
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Priority to AU14048/83A priority patent/AU556110B2/en
Publication of AU1404883A publication Critical patent/AU1404883A/en
Application granted granted Critical
Publication of AU556110B2 publication Critical patent/AU556110B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU14048/83A 1978-01-26 1983-04-28 9-deoxy-9a-methylene isoesters of pg12 Ceased AU556110B2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT7819616A IT7819616A0 (en) 1978-01-26 1978-01-26 9-DEOXY-9A-METHYLENE-ISOSTERES OF PGI 2.
ZA79268A ZA79268B (en) 1978-01-26 1979-01-23 9-deoxy-9a-methylene isosteres of pgi2 and process for their preparation
CS804928A CS215150B2 (en) 1978-01-26 1979-01-23 Method of making the 9-deoxy-9a-methylenisosters of the prostacycline pgi2
CS79513A CS215149B2 (en) 1978-01-26 1979-01-23 Method of making the 9-deoxy-9a-methylenisosters of the prostacycline
KR7900219A KR840000948B1 (en) 1978-01-26 1979-01-25 Method for producing 9-deoxy-9a-methylene iso-electron body of PGI_2
HU79EA191A HU182726B (en) 1978-01-26 1979-01-25 Process for producing the 9-desoxy-9a-methylene-isosteres of pgi2/prostacyclin/
BE193094A BE873731A (en) 1978-01-26 1979-01-26 9-DEOXY-9A-METHYLENE ISOSTERES OF PG12 AND METHOD FOR PREPARING THEM
SU802930648A SU1360582A3 (en) 1978-01-26 1980-06-05 Method of producing 9-dioxi-9a-methylene isosters or their lactones
AU14048/83A AU556110B2 (en) 1978-01-26 1983-04-28 9-deoxy-9a-methylene isoesters of pg12

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT7819616A IT7819616A0 (en) 1978-01-26 1978-01-26 9-DEOXY-9A-METHYLENE-ISOSTERES OF PGI 2.
IT1961678 1978-01-26
IT3107378 1978-12-21
KR7900219A KR840000948B1 (en) 1978-01-26 1979-01-25 Method for producing 9-deoxy-9a-methylene iso-electron body of PGI_2
AU14048/83A AU556110B2 (en) 1978-01-26 1983-04-28 9-deoxy-9a-methylene isoesters of pg12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU43438/79A Division AU530571B2 (en) 1978-01-26 1979-01-17 9-deoxy-9a-methylene-isosteres of pgi2

Publications (2)

Publication Number Publication Date
AU1404883A AU1404883A (en) 1984-01-12
AU556110B2 true AU556110B2 (en) 1986-10-23

Family

ID=36794902

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14048/83A Ceased AU556110B2 (en) 1978-01-26 1983-04-28 9-deoxy-9a-methylene isoesters of pg12

Country Status (8)

Country Link
KR (1) KR840000948B1 (en)
AU (1) AU556110B2 (en)
BE (1) BE873731A (en)
CS (2) CS215150B2 (en)
HU (1) HU182726B (en)
IT (1) IT7819616A0 (en)
SU (1) SU1360582A3 (en)
ZA (1) ZA79268B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56145239A (en) * 1980-04-11 1981-11-11 Sumitomo Chem Co Ltd Novel bicyclooctane derivative and its preparation
JPS61280294A (en) * 1985-06-04 1986-12-10 Nisshin Flour Milling Co Ltd Optically active carbacycline intermediate and production thereof
US4837342A (en) * 1986-02-28 1989-06-06 Sagami Chemical Research Center Prostacyclin analogue, and blood circulation improving agent and anti-ulcer composition containing it as active ingredient

Also Published As

Publication number Publication date
AU1404883A (en) 1984-01-12
KR840000948B1 (en) 1984-07-01
BE873731A (en) 1979-07-26
CS215149B2 (en) 1982-07-30
KR830000687A (en) 1983-04-18
CS215150B2 (en) 1982-07-30
SU1360582A3 (en) 1987-12-15
IT7819616A0 (en) 1978-01-26
HU182726B (en) 1984-03-28
ZA79268B (en) 1980-01-30

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