DE68909772D1 - Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe. - Google Patents

Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe.

Info

Publication number
DE68909772D1
DE68909772D1 DE89103022T DE68909772T DE68909772D1 DE 68909772 D1 DE68909772 D1 DE 68909772D1 DE 89103022 T DE89103022 T DE 89103022T DE 68909772 T DE68909772 T DE 68909772T DE 68909772 D1 DE68909772 D1 DE 68909772D1
Authority
DE
Germany
Prior art keywords
active ingredient
extended release
diclofenac sodium
drug preparation
sodium drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89103022T
Other languages
English (en)
Other versions
DE68909772T2 (de
Inventor
Yoichi C O Dojin Iy Sawayanagi
Yoshiharu C O Dojin Iyak Otani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dojin Iyaku Kako Co Ltd
Original Assignee
Dojin Iyaku Kako Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dojin Iyaku Kako Co Ltd filed Critical Dojin Iyaku Kako Co Ltd
Application granted granted Critical
Publication of DE68909772D1 publication Critical patent/DE68909772D1/de
Publication of DE68909772T2 publication Critical patent/DE68909772T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE89103022T 1989-02-17 1989-02-21 Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe. Expired - Fee Related DE68909772T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA000591456A CA1323576C (en) 1989-02-17 1989-02-17 Long acting diclofenac sodium preparation
EP89103022A EP0383967B1 (de) 1989-02-17 1989-02-21 Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe

Publications (2)

Publication Number Publication Date
DE68909772D1 true DE68909772D1 (de) 1993-11-11
DE68909772T2 DE68909772T2 (de) 1994-05-11

Family

ID=25672457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89103022T Expired - Fee Related DE68909772T2 (de) 1989-02-17 1989-02-21 Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe.

Country Status (4)

Country Link
US (1) US4948581A (de)
EP (1) EP0383967B1 (de)
CA (1) CA1323576C (de)
DE (1) DE68909772T2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9002336A (nl) * 1990-10-24 1992-05-18 Leuven K U Res & Dev Bekledings- of matrixmateriaal voor geneesmiddelen.
DE4108239A1 (de) * 1991-03-14 1992-09-17 Merck Patent Gmbh Pellets enthaltend natriummonofluorphosphat
EP0520119A1 (de) * 1991-06-17 1992-12-30 Spirig Ag Pharmazeutische Präparate Neue orale Diclofenaczubereitung
EP0592569A1 (de) * 1991-07-03 1994-04-20 Sano Corporation Zusammensetzung und verfahren zur transdermalen verabreichung von diclofenac
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
US6312724B1 (en) 1997-04-04 2001-11-06 Isa Odidi Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof
DE19928312A1 (de) * 1999-06-16 2000-12-21 Schering Ag Arzneimittelzubereitung mit verzögerter Wirkstoffabgabe
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
HRP20020124A2 (en) * 2002-02-11 2003-10-31 Pliva D D Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping
PT1492531E (pt) 2002-04-09 2008-12-10 Flamel Tech Sa Formulação farmacêutica oral sob a forma de suspensão aquosa de microcápsulas que permite a libertação modificada de amoxicilina
DE60325709D1 (de) 2002-04-09 2009-02-26 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
AR057181A1 (es) * 2005-11-30 2007-11-21 Astra Ab Nueva forma de dosificacion de combinacion
US7662858B2 (en) * 2008-05-23 2010-02-16 Aaipharma, Inc. Method of treating post-surgical acute pain
CN102209529A (zh) 2008-09-09 2011-10-05 阿斯利康(瑞典)有限公司 将药物组合物递送至有需要的患者的方法
JP2012531409A (ja) 2009-06-25 2012-12-10 アストラゼネカ・アクチエボラーグ Ｎｓａｉｄ関連潰瘍を発症するリスクがある患者の処置方法
CN102638978A (zh) * 2009-06-25 2012-08-15 波曾公司 用于治疗需要阿司匹林治疗之患者的方法
US20120183611A1 (en) * 2009-09-25 2012-07-19 Norvartis Ag Oral pharmaceutical composition comprising diclofenac
WO2012059937A1 (en) * 2010-11-01 2012-05-10 Abbott Healthcare Private Limited Modifies release pharmaceutical compositons for nsaids
US20130084313A1 (en) * 2011-09-30 2013-04-04 Stomavite, Llc Supplement for ostomy patients
EA028049B1 (ru) 2011-12-28 2017-10-31 Поузен Инк. Улучшенные композиции и способы доставки омепразола и ацетилсалициловой кислоты
RU2602681C1 (ru) * 2015-11-09 2016-11-20 Федеральное государственное бюджетное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (ФГБОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России) Способ получения капсул диклофенака
CN109646412B (zh) * 2018-12-12 2021-07-02 中国药科大学 一种肠溶药用组合物及其制备方法和应用
CN110893175A (zh) * 2019-12-04 2020-03-20 仁和堂药业有限公司 一种双氯芬酸钠肠溶片
CN110893174A (zh) * 2019-12-04 2020-03-20 仁和堂药业有限公司 双氯芬酸钠肠溶片的制备方法
CN111700872A (zh) * 2020-07-20 2020-09-25 华益药业科技(安徽)有限公司 一种双氯芬酸肠溶片及其加工工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6144811A (ja) * 1984-08-10 1986-03-04 Ss Pharmaceut Co Ltd 徐放性ジクロフエナクナトリウム製剤
CH666405A5 (de) * 1985-06-24 1988-07-29 Ciba Geigy Ag Feste, haltbare darreichungsformen mit elastischem filmueberzug.
IT1200178B (it) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
IT1215726B (it) * 1988-01-18 1990-02-22 Alfa Wassermann Spa Formulazioni galeniche a cessione programmata.

Also Published As

Publication number Publication date
DE68909772T2 (de) 1994-05-11
US4948581A (en) 1990-08-14
EP0383967B1 (de) 1993-10-06
EP0383967A1 (de) 1990-08-29
CA1323576C (en) 1993-10-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee