DK125021B - Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds. - Google Patents

Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds.

Info

Publication number: DK125021B
Authority: DK; Denmark
Prior art keywords: tetrahydro; phenyl; preparation; acid addition; addition salts
Prior art date: 1970-01-06

Application number

DK2571AA

Other languages

Danish (da)

Inventor

A Rheiner

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-01-06

Filing date

1971-01-05

Publication date

1972-12-18

1971-01-05 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1972-12-18 Publication of DK125021B publication Critical patent/DK125021B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK2571AA 1970-01-06 1971-01-05 Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds. DK125021B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH10370A CH527194A (en)	1970-01-06	1970-01-06	Process for the preparation of isoquinoline derivatives

Publications (1)

Publication Number	Publication Date
DK125021B true DK125021B (en)	1972-12-18

Family

ID=4179328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK2571AA DK125021B (en)	1970-01-06	1971-01-05	Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds.

Country Status (19)

Country	Link
JP (1)	JPS5515476B1 (en)
AT (1)	AT303041B (en)
BE (1)	BE761219A (en)
CA (1)	CA999866A (en)
CH (2)	CH538477A (en)
DE (1)	DE2062001C2 (en)
DK (1)	DK125021B (en)
ES (1)	ES387016A1 (en)
FI (1)	FI49503C (en)
FR (1)	FR2081412B1 (en)
GB (1)	GB1335261A (en)
IE (1)	IE34859B1 (en)
IL (1)	IL35916A (en)
NL (1)	NL171444C (en)
NO (1)	NO135315C (en)
PH (1)	PH9682A (en)
SE (3)	SE386672B (en)
YU (1)	YU33660B (en)
ZA (1)	ZA708590B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4719216A (en) *	1983-06-23	1988-01-12	Mcneilab, Inc.	Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
ZA844402B (en) *	1983-06-23	1986-01-29	Mcneil Pharmaceutical	Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) *	1983-06-23	1986-06-17	Mcneilab, Inc.	Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) *	1992-10-14	1994-04-20	Merck & Co Inc	HIV integrase inhibitors
AU781179B2 (en)	1999-11-03	2005-05-12	Albany Molecular Research, Inc.	Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) *	1999-11-03	2007-01-16	Amr Technology, Inc.	4-phenyl substituted tetrahydroisoquinolines and use thereof
RU2293728C2 (en) *	1999-11-03	2007-02-20	Эймр Текнолоджи, Инк.	Derivatives of tetrahydroisoquinoline, pharmaceutical composition containing thereof, method for inhibition of synaptic uptake of dopamine and treatment method
EP1113007A1 (en)	1999-12-24	2001-07-04	Pfizer Inc.	Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
MXPA03000275A (en)	2000-07-11	2004-12-13	Albany Molecular Res Inc	Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof.
MX2007000428A (en)	2004-07-15	2008-03-05	Amr Technology Inc	Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin.
JP2008543880A (en)	2005-06-17	2008-12-04	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Naphthyridine compounds
UA95454C2 (en)	2005-07-15	2011-08-10	Амр Текнолоджи, Інк.	Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AR071997A1 (en)	2008-06-04	2010-07-28	Bristol Myers Squibb Co	CRYSTAL FORM OF 6 - ((4S) -2-METHYL-4- (2-NAFTIL) -1,2,3,4-TETRAHYDROISOQUINOLIN-7-IL) PIRIDAZIN-3-AMINA
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
KR20120023072A (en)	2009-05-12	2012-03-12	브리스톨-마이어스 스큅 컴퍼니	Crystalline forms of (s)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorohphenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
MX2011011907A (en)	2009-05-12	2012-01-20	Albany Molecular Res Inc	7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4- tetrahydroisoquinoline and use thereof.
MX2011011901A (en)	2009-05-12	2012-01-20	Albany Molecular Res Inc	Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670694B2 (en) *	1966-05-05	1976-07-22	Hoechst Ag, 6000 Frankfurt	METHOD FOR MANUFACTURING TETRAHYDROISOCHINOLINES

1970
- 1970-01-06 CH CH1011872A patent/CH538477A/en not_active IP Right Cessation
- 1970-01-06 CH CH10370A patent/CH527194A/en not_active IP Right Cessation
- 1970-12-16 SE SE7313623A patent/SE386672B/en unknown
- 1970-12-16 DE DE2062001A patent/DE2062001C2/en not_active Expired
- 1970-12-16 SE SE17063/70A patent/SE368401B/xx unknown
- 1970-12-21 ZA ZA708590A patent/ZA708590B/en unknown
- 1970-12-28 IL IL35916A patent/IL35916A/en unknown
- 1970-12-29 NL NLAANVRAGE7018956,A patent/NL171444C/en not_active IP Right Cessation
- 1970-12-31 FI FI703519A patent/FI49503C/en active
1971
- 1971-01-04 IE IE6/71A patent/IE34859B1/en unknown
- 1971-01-05 AT AT4571A patent/AT303041B/en not_active IP Right Cessation
- 1971-01-05 ES ES387016A patent/ES387016A1/en not_active Expired
- 1971-01-05 FR FR7100097A patent/FR2081412B1/fr not_active Expired
- 1971-01-05 DK DK2571AA patent/DK125021B/en not_active IP Right Cessation
- 1971-01-05 GB GB45471A patent/GB1335261A/en not_active Expired
- 1971-01-05 BE BE761219A patent/BE761219A/en not_active IP Right Cessation
- 1971-01-05 NO NO7121A patent/NO135315C/no unknown
- 1971-01-06 YU YU19/71A patent/YU33660B/en unknown
- 1971-01-06 JP JP7194A patent/JPS5515476B1/ja active Pending
- 1971-01-06 CA CA102,060A patent/CA999866A/en not_active Expired
- 1971-01-07 PH PH12087*UA patent/PH9682A/en unknown
1973
- 1973-10-05 SE SE7313622A patent/SE399879B/en unknown

Also Published As

Publication number	Publication date
DE2062001A1 (en)	1971-07-15
FI49503C (en)	1975-07-10
NO135315C (en)	1977-03-23
SE368401B (en)	1974-07-01
IL35916A0 (en)	1971-02-25
SE399879B (en)	1978-03-06
GB1335261A (en)	1973-10-24
JPS5515476B1 (en)	1980-04-23
YU33660B (en)	1977-12-31
CA999866A (en)	1976-11-16
NL171444C (en)	1983-04-05
IE34859B1 (en)	1975-09-03
FR2081412B1 (en)	1974-04-12
NL7018956A (en)	1971-07-08
IL35916A (en)	1973-11-28
IE34859L (en)	1971-07-06
PH9682A (en)	1976-02-10
AT303041B (en)	1972-11-10
ZA708590B (en)	1971-09-29
CH527194A (en)	1972-08-31
NL171444B (en)	1982-11-01
YU1971A (en)	1977-06-30
CH538477A (en)	1973-06-30
FI49503B (en)	1975-04-01
FR2081412A1 (en)	1971-12-03
BE761219A (en)	1971-07-05
ES387016A1 (en)	1976-05-01
NO135315B (en)	1976-12-13
DE2062001C2 (en)	1986-10-16
SE386672B (en)	1976-08-16

Similar Documents

Publication	Publication Date	Title
DK129446B (en)	1974-10-14	Analogous process for the preparation of phenoxyhydroxypropylamines or acid addition salts thereof.
DK124547B (en)	1972-10-30	Analogous process for the preparation of (3-amino-2-hydroxy-propyloxy) -thiochroman derivatives or acid addition salts thereof.
DK131858B (en)	1975-09-15	Analogous process for the preparation of 4-amino-6-arylpyrimidine compounds or acid addition salts thereof.
DK125021B (en)	1972-12-18	Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds.
DK131721B (en)	1975-08-25	Analogous process for the preparation of adamantanylamines or 3,5,7-trimethylhomologous or acid addition salts thereof.
DK139575B (en)	1979-03-12	Analogous process for the preparation of 2-aminomethylene-1-indanone compounds or acid addition salts thereof.
DK137382B (en)	1978-02-27	Analogous process for the preparation of 2,2-diaryl-4- (4'-aryl-4'-hydroxy-piperidine) butyramides or acid addition salts thereof.
DK139582B (en)	1979-03-12	Analogous process for the preparation of racemic or optically active benzocycloheptaisoquinoline compounds or acid addition salts thereof.
DK136722B (en)	1977-11-14	Analogous process for the preparation of oxazolidinone (2) derivatives or acid addition salts thereof.
DK127424B (en)	1973-11-05	Analogous process for the preparation of 4-aryl-1- (4,4-diarylbutyl) -4-hydroxypiperidines or acid addition salts thereof.
DK134233B (en)	1976-10-04	Analogous process for the preparation of substituted benzimidazolinones or triazaspiro- [4,5] -decan-4-ones or acid addition salts thereof.
DK137044B (en)	1978-01-09	Analogous process for the preparation of 4,4-diphenylhexahydroazepine derivatives or acid addition salts thereof.
DK129164B (en)	1974-09-02	Analogous process for the preparation of 3-alkyl-5-aryloxymethylisoxazoles or acid addition salts thereof.
DK129718B (en)	1974-11-11	Analogous process for the preparation of thiazolino-pyrimidin-5-ones or their acid addition salts or the corresponding optically active compounds.
DK133677B (en)	1976-06-28	Analogous process for the preparation of 2-alkyl-4- (1-alkyl-4-piperidylidene) -benzocycloheptathiophene derivatives or acid addition salts thereof.
DK135374B (en)	1977-04-18	Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidines or acid addition salts thereof.
DK137834B (en)	1978-05-16	Analogous process for the preparation of triazolobenzodiazepine derivatives or acid addition salts thereof.
DK132551B (en)	1975-12-29	Analogous process for the preparation of racemic or optically active carbamoylalkoxyphenoxyisopropanolamine derivatives or acid addition salts thereof.
DK131570B (en)	1975-08-04	Analogous process for the preparation of thienylalkane derivatives or acid addition salts thereof.
DK136152B (en)	1977-08-22	Analogous process for the preparation of 1-aminomethyl derivatives of 2,2-diarylclopropanes or acid addition salts thereof.
DK125593B (en)	1973-03-12	Analogous process for the preparation of 7-acyl-1,2,4,5-tetrahydro- (3H) -3-benzazepines or acid addition salts thereof.
DK134717B (en)	1977-01-03	Analogous process for the preparation of substituted m-dioxane-5-methylamines or acid addition salts thereof.
DK129839B (en)	1974-11-25	Analogous process for the preparation of N-vinylquinolones or acid addition salts thereof.
DK135576B (en)	1977-05-23	Analogous process for the preparation of 1,4-methano- or 1,4-ethano-tetrahydronaphthyloxyaminopropanols or acid addition salts thereof.
DK130982B (en)	1975-05-12	Analogous process for the preparation of esters of alpha-amino- (1,4-cyclohexadienyl) -methylpenicillin or acid addition salts thereof.

Legal Events

Date	Code	Title	Description
1988-09-19	PBP	Patent lapsed