DK159453C - METHOD FOR PREPARING 5'-DEOXY-5'-METHYLTHIOADENOSINE - Google Patents

METHOD FOR PREPARING 5'-DEOXY-5'-METHYLTHIOADENOSINE

Info

Publication number: DK159453C
Authority: DK; Denmark
Prior art keywords: methylthioadenosine; deoxy; preparing
Prior art date: 1980-04-22

Application number

DK176481A

Other languages

Danish (da)

Other versions

DK176481A (en

DK159453B (en

Inventor

Giorgio Stramentinoli

Federico Gennari

Original Assignee

Bioresearch Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-04-22

Filing date

1981-04-21

Publication date

1991-03-18

1981-04-21 Application filed by Bioresearch Srl filed Critical Bioresearch Srl

1981-10-23 Publication of DK176481A publication Critical patent/DK176481A/en

1984-01-20 Priority to DK25184A priority Critical patent/DK163518C/en

1990-10-15 Publication of DK159453B publication Critical patent/DK159453B/en

1991-03-18 Application granted granted Critical

1991-03-18 Publication of DK159453C publication Critical patent/DK159453C/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK176481A 1980-04-22 1981-04-21 METHOD FOR PREPARING 5'-DEOXY-5'-METHYLTHIOADENOSINE DK159453C (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK25184A DK163518C (en)	1980-04-22	1984-01-20	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE ADENOSIN DERIVATIVES

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT21550/80A IT1193529B (en)	1980-04-22	1980-04-22	ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE
IT2155080		1980-04-22

Publications (3)

Publication Number	Publication Date
DK176481A DK176481A (en)	1981-10-23
DK159453B DK159453B (en)	1990-10-15
DK159453C true DK159453C (en)	1991-03-18

Family

ID=11183457

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK176481A DK159453C (en)	1980-04-22	1981-04-21	METHOD FOR PREPARING 5'-DEOXY-5'-METHYLTHIOADENOSINE

Country Status (17)

Country	Link
JP (2)	JPS56166117A (en)
AR (1)	AR231144A1 (en)
BE (1)	BE888472A (en)
CA (1)	CA1198105A (en)
CH (2)	CH645544A5 (en)
DE (1)	DE3116067A1 (en)
DK (1)	DK159453C (en)
ES (2)	ES501539A0 (en)
FI (1)	FI70227C (en)
FR (1)	FR2491761A1 (en)
GB (3)	GB2074446B (en)
IT (1)	IT1193529B (en)
LU (1)	LU83307A1 (en)
MX (1)	MX9203630A (en)
NL (1)	NL192111C (en)
NO (1)	NO150515C (en)
SE (3)	SE460198B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1177373B (en) *	1984-12-06	1987-08-26	Bioresearch Spa	SALTS OF 5'-METHYLLIUM-5'-DEOXYDENOSINE WITH LONG ALCHYLIC CHAIN SULPHONIC ACIDS
IT1227049B (en) *	1988-07-29	1991-03-14	Bioresearch Spa	USE OF ADENOSINIC DERIVATIVES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS HAVING IMMUNOSTIMULATING ACTIVITIES.
JPH0497287A (en) *	1990-08-10	1992-03-30	Nec Ic Microcomput Syst Ltd	Picture display integrated circuit
ES2259552B1 (en) *	2005-03-17	2007-06-16	Proyecto De Biomedicina Cima, S.L.	EMPLOYMENT OF 5'-METHYLTIOENENINE (MTA) IN THE PREVENTION AND / OR TREATMENT OF AUTOIMMUNE DISEASES AND / OR REPLACEMENT OF TRANSPLANTS.
EP1891961B1 (en) *	2005-03-17	2009-09-16	Proyecto de Biomedicina Cima, S.L.	Use of 5'-methylthioadenosine (mta) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection
DE102010027595A1 (en) *	2010-07-23	2012-01-26	Helmut Vorbrüggen	Clinical application of adenosine derivative, preferably (dihydroxyphenyl)ethyl-amino-purin-9-yl-(hydroxymethyl)oxolane-diol, for reducing body temperature during impending ischemia of brain vessels, which occur during heart attacks
DE102011005232A1 (en) *	2011-03-08	2012-09-13	AristoCon GmbH & Co. KG	Adenosine and its derivatives for use in pain therapy
WO2014163152A1 (en) *	2013-04-05	2014-10-09	ライオン株式会社	Non-rem sleep-promoting agent, deep sleep-promoting agent and natural sleep-inducing agent
CN105102609B (en) *	2013-04-05	2018-07-20	狮王株式会社	Yeast culture and internal composition
KR102245628B1 (en) *	2013-04-05	2021-04-28	라이온 가부시키가이샤	Composition for internal use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1259341B (en) *	1962-12-22	1968-01-25	Boehringer & Soehne Gmbh	Process for the preparation of new 5'-sulfoxides of nucleosides
DE1545645A1 (en) *	1965-12-06	1969-08-21	Boehringer Mannheim Gmbh	Process for the preparation of disubstituted adenosine derivatives
GB1436509A (en) *	1973-11-27	1976-05-19	Ajinomoto Kk	Method for producing s-adenosylmethionine or methylthioadenosine from yeast
FR2313937A1 (en) *	1975-06-09	1977-01-07	Anvar	DRUG BASED ON 5 'THIOETHERS OF ADENOSINE
FR2424027A1 (en) *	1978-04-28	1979-11-23	Merieux Inst	NEW MEDICINAL PRODUCT, IN PARTICULAR SEDATIVE AND SLEEP INDUCER AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

1980
- 1980-04-22 IT IT21550/80A patent/IT1193529B/en active
1981
- 1981-04-17 BE BE0/204529A patent/BE888472A/en not_active IP Right Cessation
- 1981-04-21 AR AR285020A patent/AR231144A1/en active
- 1981-04-21 ES ES501539A patent/ES501539A0/en active Granted
- 1981-04-21 CA CA000375784A patent/CA1198105A/en not_active Expired
- 1981-04-21 LU LU83307A patent/LU83307A1/en unknown
- 1981-04-21 NO NO811346A patent/NO150515C/en unknown
- 1981-04-21 SE SE8102489A patent/SE460198B/en not_active IP Right Cessation
- 1981-04-21 DK DK176481A patent/DK159453C/en not_active IP Right Cessation
- 1981-04-21 JP JP5930181A patent/JPS56166117A/en active Granted
- 1981-04-22 CH CH263281A patent/CH645544A5/en not_active IP Right Cessation
- 1981-04-22 NL NL8101984A patent/NL192111C/en not_active IP Right Cessation
- 1981-04-22 CH CH4716/84A patent/CH650514A5/en not_active IP Right Cessation
- 1981-04-22 GB GB8112428A patent/GB2074446B/en not_active Expired
- 1981-04-22 FI FI811249A patent/FI70227C/en not_active IP Right Cessation
- 1981-04-22 DE DE19813116067 patent/DE3116067A1/en active Granted
- 1981-04-22 FR FR8107992A patent/FR2491761A1/en active Granted
1982
- 1982-04-01 ES ES511039A patent/ES511039A0/en active Granted
1983
- 1983-08-15 GB GB08321947A patent/GB2144409B/en not_active Expired
1984
- 1984-05-25 GB GB08413454A patent/GB2144038B/en not_active Expired
1987
- 1987-03-04 SE SE8700914A patent/SE464635B/en not_active IP Right Cessation
- 1987-03-04 SE SE8700913A patent/SE466238B/en not_active IP Right Cessation
1989
- 1989-02-02 JP JP1022771A patent/JPH01301692A/en active Granted
1992
- 1992-06-26 MX MX9203630A patent/MX9203630A/en unknown

Also Published As

Publication number	Publication date
ES8206551A1 (en)	1982-08-16
DK176481A (en)	1981-10-23
GB8321947D0 (en)	1983-09-14
NO811346L (en)	1981-10-23
GB2144409B (en)	1985-09-11
GB8413454D0 (en)	1984-07-04
NO150515B (en)	1984-07-23
DE3116067C2 (en)	1992-12-17
SE8700914L (en)	1987-03-04
SE8700913L (en)	1987-03-04
ES501539A0 (en)	1982-08-16
FI70227C (en)	1986-09-15
JPS56166117A (en)	1981-12-21
FI811249L (en)	1981-10-23
DE3116067A1 (en)	1982-03-11
CH650514A5 (en)	1985-07-31
FR2491761A1 (en)	1982-04-16
CH645544A5 (en)	1984-10-15
NL8101984A (en)	1981-11-16
FI70227B (en)	1986-02-28
IT8021550A0 (en)	1980-04-22
SE460198B (en)	1989-09-18
LU83307A1 (en)	1981-07-24
SE8700914D0 (en)	1987-03-04
SE466238B (en)	1992-01-20
ES8306378A1 (en)	1983-06-01
GB2144409A (en)	1985-03-06
CA1198105A (en)	1985-12-17
JPH0246599B2 (en)	1990-10-16
NL192111B (en)	1996-10-01
GB2074446A (en)	1981-11-04
BE888472A (en)	1981-08-17
JPH0249288B2 (en)	1990-10-29
NL192111C (en)	1997-02-04
JPH01301692A (en)	1989-12-05
GB2144038B (en)	1985-08-29
GB2144038A (en)	1985-02-27
IT1193529B (en)	1988-07-08
AR231144A1 (en)	1984-09-28
MX9203630A (en)	1992-09-01
DK159453B (en)	1990-10-15
SE464635B (en)	1991-05-27
NO150515C (en)	1984-10-31
ES511039A0 (en)	1983-06-01
FR2491761B1 (en)	1984-01-06
SE8102489L (en)	1981-10-23
SE8700913D0 (en)	1987-03-04
GB2074446B (en)	1985-04-11

Legal Events

Date	Code	Title	Description
1997-12-22	PBP	Patent lapsed

Publication	Publication Date	Title
DK411081A (en)	1982-03-17	PROCEDURE FOR PREPARING NUCLEOSIDE ANALYSIS
DK280182A (en)	1982-12-24	METHOD FOR PREPARING N-ARYL-PIPERAZINAL CANAMIDES
KR860005574A (en)	1986-07-23	Method for preparing nucleoside derivatives
DK379985D0 (en)	1985-08-21	METHOD FOR PREPARING 6-CHLOR-N-METHYL-2,3,4,5-TETRAHYDRO-LH-BENZAZEPINE
DK262782A (en)	1982-12-13	METHOD FOR PREPARING N-DIHYDROTHIAZOLYL-3-QUINOLINCARBOXAMIDE DERIVATIVES
KR900002683A (en)	1990-02-28	Method for preparing naphthoquinones
DK159453C (en)	1991-03-18	METHOD FOR PREPARING 5'-DEOXY-5'-METHYLTHIOADENOSINE
DK157855C (en)	1990-07-30	METHOD FOR PREPARING 2,3-DICHLOR-5-TRICHLORMETHYLPYRIDINE
DK370781A (en)	1982-02-23	METHOD FOR PREPARING 3,4-BIS-PHENYL-1,2,4-TRIAZOLES
DK159158C (en)	1991-03-11	METHOD FOR PENICILLANOYLOXY-METHYLPENICILLANATE-1,1,1 ', 1'-TETRAOXIDE PREPARATION
KR860004922A (en)	1986-07-16	Method for preparing N-formyl-α-aspartylphenylalanine
IT1171282B (en)	1987-06-10	ADENOSINE N6-REPLACE
DK370582A (en)	1983-02-20	METHOD FOR PREPARING 2-BETA-D-RIBOFURANOSYLTHIAZOL-4-CARBOXAMIDE
DK115581A (en)	1981-09-28	METHOD FOR PREPARING PYRIMIDYLQUINAZOLINES
DK316981A (en)	1982-01-18	METHOD FOR PENTAPEPTID PREPARATION
KR860004919A (en)	1986-07-16	Method for preparing nucleoside derivatives
DK113483A (en)	1983-03-08	METHOD FOR PREPARING 3,4-DIPHENYL-5-METHYLPYRAZOLE DERIVATIVES
DK188881A (en)	1981-10-30	METHOD FOR PREPARING 2-GUANIDINTHIAZOL DERIVATIVES
DK449881A (en)	1981-10-12	METHOD FOR PREPARING MOROXYDINPHENOXYISOBUTYRATES
DK513580A (en)	1981-07-08	METHOD FOR PREPARING 4,5-DIARYL-ALFA (POLYHALOGENALKYL) -1H-IMIDAZOL-2-METHANOLS
DK152131C (en)	1988-06-20	METHOD FOR PREPARING 5,6,7,7A-TETRAHYDRO-4H-THIENO (3,2-C) -PYRIDIN-2-ON DERIVATIVES
DK71681A (en)	1981-08-20	METHOD FOR PIPERIDINOKINAZOLINE PREPARATION
DK480781A (en)	1982-05-29	METHOD FOR PREPARING 5,6,7,7A-TETRAHYDRO-4H-THIENO (3,2-C) PYRIDIN-2-ON-DE-RIVATES
DK99582A (en)	1982-09-10	METHOD FOR PREPARING 4-FLUORAZETIDINONES
DK157999C (en)	1990-08-13	METHOD FOR PREPARING 5,11-DIHYDRO-6H-PYRIDOOE2,3-BAAOE1,4AABENZODIAZEPIN-6-ONER