DK35984A - LACTAMPEPTIDES AND THEIR PREPARATION AND USE - Google Patents

LACTAMPEPTIDES AND THEIR PREPARATION AND USE Download PDF

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Publication number
DK35984A
DK35984A DK35984A DK35984A DK35984A DK 35984 A DK35984 A DK 35984A DK 35984 A DK35984 A DK 35984A DK 35984 A DK35984 A DK 35984A DK 35984 A DK35984 A DK 35984A
Authority
DK
Denmark
Prior art keywords
lactampeptides
preparation
Prior art date
Application number
DK35984A
Other languages
Danish (da)
Other versions
DK35984D0 (en
Inventor
William Bencze
Bruno Kamber
Angelo Storni
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK35984D0 publication Critical patent/DK35984D0/en
Publication of DK35984A publication Critical patent/DK35984A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK35984A 1983-01-27 1984-01-26 LACTAMPEPTIDES AND THEIR PREPARATION AND USE DK35984A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH45483 1983-01-27

Publications (2)

Publication Number Publication Date
DK35984D0 DK35984D0 (en) 1984-01-26
DK35984A true DK35984A (en) 1984-07-28

Family

ID=4187392

Family Applications (1)

Application Number Title Priority Date Filing Date
DK35984A DK35984A (en) 1983-01-27 1984-01-26 LACTAMPEPTIDES AND THEIR PREPARATION AND USE

Country Status (12)

Country Link
EP (1) EP0115473A3 (en)
JP (1) JPS59141544A (en)
KR (1) KR840007570A (en)
AU (1) AU2383984A (en)
DD (1) DD215539A5 (en)
DK (1) DK35984A (en)
FI (1) FI840261A (en)
GR (1) GR81747B (en)
IL (1) IL70791A0 (en)
NO (1) NO840311L (en)
PT (1) PT78008B (en)
ZA (1) ZA84595B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190378B (en) * 1985-06-21 1988-02-16 Isf Spa PYROLIDONIC DERIVATIVES
US5021568A (en) * 1988-04-22 1991-06-04 Shipov Alexandr G Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same
JP2997488B2 (en) * 1989-12-25 2000-01-11 興研株式会社 Tumor cell growth inhibitor
CA3231236A1 (en) * 2021-09-30 2023-04-06 Protinhi B.V. Protease inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT360980B (en) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works METHOD FOR PRODUCING N-ALKYLAMIDES OF 2-OXO-1-PYRROLIDINE
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
US4254107A (en) * 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin

Also Published As

Publication number Publication date
AU2383984A (en) 1984-08-02
KR840007570A (en) 1984-12-08
PT78008B (en) 1986-06-18
ZA84595B (en) 1984-11-28
DD215539A5 (en) 1984-11-14
DK35984D0 (en) 1984-01-26
FI840261A (en) 1984-07-28
IL70791A0 (en) 1984-04-30
NO840311L (en) 1984-07-30
GR81747B (en) 1984-12-12
EP0115473A2 (en) 1984-08-08
EP0115473A3 (en) 1987-01-21
FI840261A0 (en) 1984-01-23
JPS59141544A (en) 1984-08-14
PT78008A (en) 1984-02-01

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Legal Events

Date Code Title Description
ATS Application withdrawn
AHB Application shelved due to non-payment