ES2077697T3 - Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos. - Google Patents

Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.

Info

Publication number
ES2077697T3
ES2077697T3 ES91102229T ES91102229T ES2077697T3 ES 2077697 T3 ES2077697 T3 ES 2077697T3 ES 91102229 T ES91102229 T ES 91102229T ES 91102229 T ES91102229 T ES 91102229T ES 2077697 T3 ES2077697 T3 ES 2077697T3
Authority
ES
Spain
Prior art keywords
pyrrolidinone
derivatives
phenoxicarbonyl
nootropic agents
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91102229T
Other languages
English (en)
Inventor
Fumiko Hamaguchi
Tatsuo Nagasaka
Einosuke Sakurai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Application granted granted Critical
Publication of ES2077697T3 publication Critical patent/ES2077697T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE DESCRIBEN DERIVADOS DE 1-FENOXICARBONIL-2-PIRROLIDONA DE LA FORMULA (1) O (1''). DONDE R ES UN GRUPO ALQUILO C SUB 1 -C SUB 6, UN GRUPO ALCOXI C SUB 1 C SUB 6, UN GRUPO NITRO O ATOMO HALOGENO Y N ES 1 O 2, Y R'' ES LA MISMA QUE R, PERO INCLUYENDO UN ATOMO DE HIDROGENO MAS. LOS COMPUESTOS DE LA FORMULA (1'') SON UTILES COMO AGENTES NOOTROPICOS.
ES91102229T 1990-02-20 1991-02-17 Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos. Expired - Lifetime ES2077697T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2039064A JP2803882B2 (ja) 1990-02-20 1990-02-20 １―フエノキシカルボニル―２―ピロリジノン誘導体

Publications (1)

Publication Number Publication Date
ES2077697T3 true ES2077697T3 (es) 1995-12-01

Family

ID=12542704

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91102229T Expired - Lifetime ES2077697T3 (es) 1990-02-20 1991-02-17 Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.

Country Status (8)

Country Link
US (1) US5140041A (es)
EP (1) EP0443474B1 (es)
JP (1) JP2803882B2 (es)
KR (1) KR0181963B1 (es)
AT (1) ATE126504T1 (es)
CA (1) CA2036630C (es)
DE (1) DE69112095T2 (es)
ES (1) ES2077697T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3038032B2 (ja) * 1991-03-25 2000-05-08 日清製粉株式会社 血小板凝集抑制薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
CA1115212A (en) * 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
CA1305148C (en) * 1987-08-19 1992-07-14 Hiromu Matsumura Carbamoylpyrrolidone derivatives and drugs for senile dementia
EP0373226B1 (en) * 1988-04-15 1994-06-15 Taiho Pharmaceutical Company, Limited Carbamoyl-2-pyrrolidinone compounds

Also Published As

Publication number Publication date
CA2036630C (en) 1997-03-18
KR0181963B1 (ko) 1999-05-01
EP0443474A2 (en) 1991-08-28
CA2036630A1 (en) 1991-08-21
JPH03246275A (ja) 1991-11-01
KR910021373A (ko) 1991-12-20
EP0443474A3 (en) 1992-04-22
US5140041A (en) 1992-08-18
DE69112095D1 (de) 1995-09-21
ATE126504T1 (de) 1995-09-15
DE69112095T2 (de) 1996-01-11
EP0443474B1 (en) 1995-08-16
JP2803882B2 (ja) 1998-09-24

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