ES386716A1 - Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES386716A1
ES386716A1 ES386716A ES386716A ES386716A1 ES 386716 A1 ES386716 A1 ES 386716A1 ES 386716 A ES386716 A ES 386716A ES 386716 A ES386716 A ES 386716A ES 386716 A1 ES386716 A1 ES 386716A1
Authority
ES
Spain
Prior art keywords
formula
translation
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES386716A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1906169A external-priority patent/CH520699A/en
Priority claimed from CH1906269A external-priority patent/CH518958A/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES386716A1 publication Critical patent/ES386716A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Process for the preparation of new thiopine derivatives of the general formula i, ** (see formula) ** In which X represents sulfur or y represents a single direct link or Y represents sulfur and x represents a single direct link, and R1 means hydrogen, an allylic or alkyl group with up to 4 carbon atoms, As well as its addition salts with inorganic or organic acids, characterized in that a compound of the formula ii is reacted, ** (see formula) ** In which X and y have the significance indicated under formula i, With an amine of the general formula iii, ** (see formula) ** In which R1 has the significance indicated under formula i, And the obtained reaction product is optionally converted with an inorganic or organic acid, into an addition salt. (Machine-translation by Google Translate, not legally binding)
ES386716A 1969-12-23 1970-12-22 Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding) Expired ES386716A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1906169A CH520699A (en) 1969-12-23 1969-12-23 Process for the preparation of new thiepine derivatives
CH1906269A CH518958A (en) 1969-12-23 1969-12-23 Cns depressant thiepin derivs

Publications (1)

Publication Number Publication Date
ES386716A1 true ES386716A1 (en) 1974-01-16

Family

ID=25722008

Family Applications (3)

Application Number Title Priority Date Filing Date
ES386716A Expired ES386716A1 (en) 1969-12-23 1970-12-22 Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)
ES386715A Expired ES386715A1 (en) 1969-12-23 1970-12-22 Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)
ES386714A Expired ES386714A1 (en) 1969-12-23 1970-12-22 Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES386715A Expired ES386715A1 (en) 1969-12-23 1970-12-22 Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)
ES386714A Expired ES386714A1 (en) 1969-12-23 1970-12-22 Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)

Country Status (18)

Country Link
JP (2) JPS4910518B1 (en)
AT (3) AT305291B (en)
BE (1) BE760676A (en)
BG (3) BG17808A3 (en)
CA (1) CA940531A (en)
CS (3) CS171701B2 (en)
DE (1) DE2063178C3 (en)
DK (1) DK124689B (en)
ES (3) ES386716A1 (en)
FI (1) FI50629C (en)
FR (1) FR2081394A1 (en)
IE (1) IE34832B1 (en)
IL (1) IL35891A (en)
NL (1) NL7018352A (en)
NO (1) NO132836C (en)
PL (1) PL81742B1 (en)
SE (1) SE358168B (en)
SU (3) SU439986A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5429746U (en) * 1977-07-30 1979-02-27
JPH0372491U (en) * 1989-11-20 1991-07-22

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1081360A (en) * 1965-08-25 1967-08-31 Spofa Vereinigte Pharma Werke Novel 4-substituted-4,5-dihydrothieno-(2,3-b)-benzo(f)thiepines and process for the preparation thereof
NL6806701A (en) * 1967-05-19 1968-11-20
SE364591B (en) * 1968-11-19 1974-02-25 Western Electric Co
FR2036006B1 (en) * 1969-03-31 1974-05-24 Takeda Chemical Industries Ltd

Also Published As

Publication number Publication date
ES386715A1 (en) 1974-01-16
SU489334A3 (en) 1975-10-25
FI50629B (en) 1976-02-02
DE2063178A1 (en) 1971-07-01
FR2081394A1 (en) 1971-12-03
JPS4910518B1 (en) 1974-03-11
CS171702B2 (en) 1976-10-29
FI50629C (en) 1976-05-10
SU439986A3 (en) 1974-08-15
IL35891A (en) 1974-05-16
NO132836B (en) 1975-10-06
ES386714A1 (en) 1974-08-16
BG17808A3 (en) 1973-12-25
AT305292B (en) 1973-02-26
IE34832L (en) 1971-06-23
NL7018352A (en) 1971-06-25
NO132836C (en) 1976-01-14
AT302309B (en) 1972-10-10
DE2063178B2 (en) 1979-08-02
SU415882A3 (en) 1974-02-15
JPS4818240B1 (en) 1973-06-04
PL81742B1 (en) 1975-08-30
BE760676A (en) 1971-06-22
AT305291B (en) 1973-02-26
CS171701B2 (en) 1976-10-29
DK124689B (en) 1972-11-13
FR2081394B1 (en) 1974-05-24
DE2063178C3 (en) 1980-04-03
CA940531A (en) 1974-01-22
IE34832B1 (en) 1975-09-03
BG17977A3 (en) 1974-03-05
SE358168B (en) 1973-07-23
CS171703B2 (en) 1976-10-29
BG17807A3 (en) 1973-12-25

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