FI914826A0 - Kinazolinderivat och deras framstaellning. - Google Patents

Kinazolinderivat och deras framstaellning.

Info

Publication number
FI914826A0
FI914826A0 FI914826A FI914826A FI914826A0 FI 914826 A0 FI914826 A0 FI 914826A0 FI 914826 A FI914826 A FI 914826A FI 914826 A FI914826 A FI 914826A FI 914826 A0 FI914826 A0 FI 914826A0
Authority
FI
Finland
Prior art keywords
kinazolinderivat
deras framstaellning
och deras
och
framstaellning
Prior art date
Application number
FI914826A
Other languages
English (en)
Other versions
FI914826A (fi
Inventor
Norihiko Shimazaki
Hitoshi Yamazaki
Takumi Yatabe
Hirokazu Tanaka
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909022306A external-priority patent/GB9022306D0/en
Priority claimed from GB919118337A external-priority patent/GB9118337D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI914826A0 publication Critical patent/FI914826A0/fi
Publication of FI914826A publication Critical patent/FI914826A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI914826A 1990-10-15 1991-10-14 Kinazolinderivat och deras framstaellning. FI914826A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909022306A GB9022306D0 (en) 1990-10-15 1990-10-15 Quinazoline derivatives and their preparation
GB919118337A GB9118337D0 (en) 1991-08-27 1991-08-27 Quinazoline derivatives and their preparation

Publications (2)

Publication Number Publication Date
FI914826A0 true FI914826A0 (fi) 1991-10-14
FI914826A FI914826A (fi) 1992-04-16

Family

ID=26297803

Family Applications (1)

Application Number Title Priority Date Filing Date
FI914826A FI914826A (fi) 1990-10-15 1991-10-14 Kinazolinderivat och deras framstaellning.

Country Status (13)

Country Link
US (1) US5304560A (fi)
EP (1) EP0481342A1 (fi)
JP (1) JP3164119B2 (fi)
KR (1) KR920008031A (fi)
CN (1) CN1060841A (fi)
AU (1) AU648110B2 (fi)
CA (1) CA2053475A1 (fi)
FI (1) FI914826A (fi)
HU (1) HUT59390A (fi)
IE (1) IE913473A1 (fi)
NO (1) NO914036L (fi)
PT (1) PT99227B (fi)
TW (1) TW201308B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE126796T1 (de) * 1990-01-02 1995-09-15 Fujisawa Pharmaceutical Co Quinazolinderivate und ihre herstellung.
US5994542A (en) * 1995-11-14 1999-11-30 Sumitomo Chemical Company, Limited Process for producing 1-substituted tetrahydroquinazolines
US6413724B1 (en) 1996-10-28 2002-07-02 Versicor, Inc. Solid phase and combinatorial library syntheses of fused 2,4-pyrimidinediones
US6025371A (en) * 1996-10-28 2000-02-15 Versicor, Inc. Solid phase and combinatorial library syntheses of fused 2,4-pyrimidinediones
US6133275A (en) * 1998-05-06 2000-10-17 Abbott Laboratories 3-phenylpyrrolidine alpha-1 adrenergic compounds
DE69917296T2 (de) * 1998-08-20 2005-05-25 Smithkline Beecham Corp. Neue substituierte triazolverbindungen
CN1216872C (zh) 1998-08-21 2005-08-31 第一三得利制药株式会社 喹唑啉衍生物及其药物用途
US6521630B1 (en) 1999-08-31 2003-02-18 Pfizer Inc. Tetrahydroquinazoline-2,4-diones and therapeutic uses thereof
US6759410B1 (en) 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
EP1235814B1 (en) 1999-11-23 2004-11-03 Smithkline Beecham Corporation 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p38 KINASE INHIBITORS
JP2003517471A (ja) * 1999-11-23 2003-05-27 スミスクライン・ビーチャム・コーポレイション ３，４−ジヒドロ−（１Ｈ）−キナゾリン−２−オンおよびそのＣＳＢＰ／ｐ３８キナーゼ阻害剤としての使用
ATE305787T1 (de) 1999-11-23 2005-10-15 Smithkline Beecham Corp 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
EP1233951B1 (en) 1999-11-23 2005-06-01 SmithKline Beecham Corporation 3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors
AU3413601A (en) * 2000-02-22 2001-09-03 Daiichi Asubio Pharma Co., Ltd. Preventive or therapeutic drugs for dermatitises containing chymase inhibitors as the active ingredient
US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
MXPA03003612A (es) 2000-10-23 2003-06-19 Smithkline Beecham Corp Compuestos novedosos.
KR20040103972A (ko) * 2002-04-19 2004-12-09 스미스클라인 비참 코포레이션 신규 화합물
WO2005026153A1 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinazoline-2, 4-diones as antibacterial agents
CN1882549B (zh) * 2003-11-20 2011-02-23 詹森药业有限公司 用作聚(adp-核糖)聚合酶抑制剂的7-苯基烷基取代的2-喹啉酮和2-喹喔啉酮
SG150533A1 (en) 2003-11-20 2009-03-30 Janssen Pharmaceutica Nv 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2- quinoxalinones as poly(adp-ribose) polymerase inhibitors
KR101159118B1 (ko) * 2003-12-05 2012-06-22 얀센 파마슈티카 엔.브이. 폴리(ａｄｐ-리보스)폴리머라제 저해제로서의 6-치환된2-퀴놀리논 및 2-퀴녹살리논
KR101286969B1 (ko) 2004-06-30 2013-07-23 얀센 파마슈티카 엔.브이. Ｐａｒｐ 저해제로서의 퀴나졸리논 유도체
AU2005259190B2 (en) * 2004-06-30 2011-05-12 Janssen Pharmaceutica N.V. Quinazolinedione derivatives as PARP inhibitors
US7803795B2 (en) * 2004-06-30 2010-09-28 Janssen Pharmaceutica N.V. Phthalazine derivatives as parp inhibitors
US7423042B2 (en) * 2005-03-25 2008-09-09 Glaxo Group Limited Compounds
WO2006104917A2 (en) * 2005-03-25 2006-10-05 Glaxo Group Limited Process for preparing pyrido[2,3-d]pyrimidin-7-one and 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one derivatives
TW200724142A (en) * 2005-03-25 2007-07-01 Glaxo Group Ltd Novel compounds
PE20100737A1 (es) * 2005-03-25 2010-11-27 Glaxo Group Ltd Nuevos compuestos
GB0507298D0 (en) * 2005-04-11 2005-05-18 Novartis Ag Organic compounds
ES2381446T3 (es) 2007-03-08 2012-05-28 Janssen Pharmaceutica, N.V. Derivado de quinolinona como inhibidores de PARP y TANK
ES2448870T3 (es) * 2007-10-26 2014-03-17 Janssen Pharmaceutica, N.V. Derivados de quinolina como inhibidores de PARP
MX2010010406A (es) 2008-03-27 2010-10-25 Janssen Pharmaceutica Nv Tetrahidrofenantridinonas y tetrahidrociclopentaquinolinonas como inhibidores de la polimerizacion de poli(adp-ribosa)polimerasa-1 y tubulina.
CA2716088C (en) * 2008-03-27 2017-03-07 Eddy Jean Edgard Freyne Quinazolinone derivatives as tubulin polymerization inhibitors
CN102786483B (zh) * 2011-05-19 2016-03-30 复旦大学 4-（4-苯基哌嗪基）喹唑啉类衍生物的药用用途
EP3332645A1 (de) 2016-12-12 2018-06-13 Bayer Cropscience AG Verwendung substituierter pyrimidindione oder jeweils deren salze als wirkstoffe gegen abiotischen pflanzenstress

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274194A (en) * 1963-03-29 1966-09-20 Miles Lab Quinazolinedione derivatives
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
US4522945A (en) * 1979-10-12 1985-06-11 Janssen Pharmaceutica N.V. (Piperidinylalkyl) quinazoline derivatives
JPS5948777B2 (ja) * 1980-07-07 1984-11-28 株式会社クボタ 厚形瓦の製造方法
JPS608274A (ja) * 1983-06-27 1985-01-17 Fujisawa Pharmaceut Co Ltd 新規キナゾリノン誘導体およびその製造法・並びに抗アレルギ−剤
US4716161A (en) * 1984-04-17 1987-12-29 Mitsubishi Chemical Industries Limited Phenylpiperazine derivatives and their acid addition salts
US4711883A (en) * 1985-09-30 1987-12-08 Ortho Pharmaceutical Corporation Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use

Also Published As

Publication number Publication date
KR920008031A (ko) 1992-05-27
FI914826A (fi) 1992-04-16
IE913473A1 (en) 1992-04-22
AU8580091A (en) 1992-04-16
JPH04261170A (ja) 1992-09-17
PT99227B (pt) 1999-04-30
JP3164119B2 (ja) 2001-05-08
HUT59390A (en) 1992-05-28
EP0481342A1 (en) 1992-04-22
CA2053475A1 (en) 1992-04-16
AU648110B2 (en) 1994-04-14
NO914036L (no) 1992-04-21
HU913243D0 (en) 1992-01-28
PT99227A (pt) 1992-09-30
NO914036D0 (no) 1991-10-14
US5304560A (en) 1994-04-19
TW201308B (fi) 1993-03-01
CN1060841A (zh) 1992-05-06

Similar Documents

Publication Publication Date Title
FI914826A (fi) Kinazolinderivat och deras framstaellning.
FI900494A (fi) Anordning foer ingaongs- och utgaongsluft och luftkonditioneringsfoerfarande.
FI912567A (fi) Ytbelaeggningskomposition och foerfarande.
FI904014A (fi) Fastklibbande materialer och deras framstaellning.
FI900479A (fi) Foerfarande och anordning foer predikterande kodning.
FI902014A0 (fi) Foerfarande och anordning foer skjutoevning.
FI83361B (fi) Fogkonstruktion och foerstycke.
FI905204A (fi) Komposteringsfoerfarande och komposteringsanlaeggning.
FI904440A (fi) Saerskilt foer raffinoerer avsedd malskiva och motsvarande raffinoer.
FI900480A0 (fi) Foerfarande och anordning foer predikterande kodning.
FI901637A0 (fi) Andningsapparat foer giftgas och roekdykning.
FI901720A0 (fi) Anordning foer kvistning och roejning.
FI901168A0 (fi) Hackelsemaskin och blaosmaskin foer bergvill.
FI901805A0 (fi) Vaextbassaengsystem och delar daertill.
FI906403A (fi) Foerfarande och odlingsenhet foer odling.
FI905693A0 (fi) Foerfarande och anordningar foer avstaonds- och koordinatmaetning.
FI900327A0 (fi) Foerfarande och anordning foer tunnplaotformning.
FI904530A0 (fi) Nedtryckningsarrangemang foer traktormaskin och arbetsmaskin.
FI904502A0 (fi) Skyddstygsprodukt och foerfarande foer framstaellning daerav.
FI904373A0 (fi) Gasavskiljare foer vaetskor och suspensioner.
FI904367A0 (fi) Kommuniceringsfoerfarande och media-apparat foer visuell kommunikation.
FI904241A0 (fi) Anordning foer byggnadsavfall och avfallscontainer.
FI904031A0 (fi) Hoernbalk och fogkonstruktion foer byggnad.
FI903825A0 (fi) Trappsteg och foerfarande foer tillverkning daerav.
FI903615A0 (fi) Borrningsfoerfarande och borrkroneapparatur.

Legal Events

Date Code Title Description
FD Application lapsed