FI954986A - Novel oral pharmaceutical preparations containing cyclosporine - Google Patents

Novel oral pharmaceutical preparations containing cyclosporine Download PDF

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Publication number
FI954986A
FI954986A FI954986A FI954986A FI954986A FI 954986 A FI954986 A FI 954986A FI 954986 A FI954986 A FI 954986A FI 954986 A FI954986 A FI 954986A FI 954986 A FI954986 A FI 954986A
Authority
FI
Finland
Prior art keywords
cyclosporine
pharmaceutical preparations
oral pharmaceutical
preparations containing
novel oral
Prior art date
Application number
FI954986A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI116120B (en
FI954986A0 (en
Inventor
Monika Petszulat
Klaus Neuer
Hatto Walch
Original Assignee
Rentschler Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25925049&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI954986(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4412201A external-priority patent/DE4412201A1/en
Application filed by Rentschler Arzneimittel filed Critical Rentschler Arzneimittel
Publication of FI954986A0 publication Critical patent/FI954986A0/en
Publication of FI954986A publication Critical patent/FI954986A/en
Application granted granted Critical
Publication of FI116120B publication Critical patent/FI116120B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

New cyclosporine-containing, oral administration pharmaceutical compositions are easy to produce and have a good bioavailability. Besides cyclosporine as active substance, these compositions contain an alkylene polyether or polyester, and may optionally contain an alkylen polyol, an alkylen glycol, a polyalkylene glycol, an alkyl diether or partial ether of a low molecular mono- or polyoxyalkane diol and/or a vegetable oil or its hydrogenated or hydrolysed product.
FI954986A 1993-04-20 1995-10-19 A novel process for the preparation of oral pharmaceutical preparations containing cyclosporin FI116120B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE4312728 1993-04-20
DE4312728 1993-04-20
DE4412201 1994-04-08
DE4412201A DE4412201A1 (en) 1993-04-20 1994-04-08 New pharmaceutical preparations for oral administration containing cyclosporin
PCT/EP1994/001228 WO1994023733A1 (en) 1993-04-20 1994-04-20 New cyclosporine-containing pharmaceutical compositions for oral administration
EP9401228 1994-04-20

Publications (3)

Publication Number Publication Date
FI954986A0 FI954986A0 (en) 1995-10-19
FI954986A true FI954986A (en) 1995-10-19
FI116120B FI116120B (en) 2005-09-30

Family

ID=25925049

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954986A FI116120B (en) 1993-04-20 1995-10-19 A novel process for the preparation of oral pharmaceutical preparations containing cyclosporin

Country Status (13)

Country Link
EP (1) EP0697881B2 (en)
JP (2) JP3862273B2 (en)
AT (1) ATE218878T1 (en)
CA (1) CA2161143A1 (en)
CZ (1) CZ291237B6 (en)
DK (1) DK0697881T3 (en)
ES (1) ES2178653T3 (en)
FI (1) FI116120B (en)
HU (1) HUT72738A (en)
NO (1) NO321076B1 (en)
PT (1) PT697881E (en)
SK (1) SK283442B6 (en)
WO (1) WO1994023733A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19545043A1 (en) * 1995-12-02 1997-06-05 Scherer Gmbh R P Pharmaceutical preparations for oral use and process for their preparation
RU2211047C2 (en) * 1997-01-30 2003-08-27 Новартис Аг Gelatin capsule with solid film including oil-free pharmaceutically compositions
ATE286403T1 (en) * 1997-03-12 2005-01-15 Abbott Lab HYDROPHILIC BINARY SYSTEMS FOR ADMINISTRATION OF CYCLOSPORINE
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
AU743098B2 (en) 1997-12-10 2002-01-17 Cyclosporine Therapeutics Limited Pharmaceutical compositions containing an omega-3 fatty acid oil
US6207179B1 (en) 2000-05-18 2001-03-27 Phoenix Scientific, Inc. Parasiticidal formulation for animals and a method of making this formulation
ES2326040T3 (en) 2001-10-19 2009-09-29 Isotechnika Inc. SYNTHESIS OF CYCLOSPORINE ANALOGS.
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
US7682433B2 (en) 2007-05-11 2010-03-23 Canon Kabushiki Kaisha Ink set, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH641356A5 (en) * 1979-02-27 1984-02-29 Sandoz Ag Pharmaceutical compositions containing cyclosporin
GB8903804D0 (en) † 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
EP0365044A3 (en) * 1984-08-02 1990-08-22 Sandoz Ag Novel pharmaceutical use of (nva)2-cyclosporine
EP0327280B1 (en) † 1988-01-29 1992-03-18 Sankyo Company Limited Cyclosporin compositions
GB2222770B (en) † 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
GB2230440B (en) * 1989-02-09 1993-05-19 Sandoz Ltd Novel cyclosporin galenic forms

Also Published As

Publication number Publication date
DK0697881T3 (en) 2002-10-07
EP0697881B1 (en) 2002-06-12
CZ291237B6 (en) 2003-01-15
HU9503019D0 (en) 1995-12-28
FI116120B (en) 2005-09-30
HUT72738A (en) 1996-05-28
ATE218878T1 (en) 2002-06-15
EP0697881A1 (en) 1996-02-28
JP2006206615A (en) 2006-08-10
SK129895A3 (en) 1997-02-05
WO1994023733A1 (en) 1994-10-27
CA2161143A1 (en) 1994-10-27
FI954986A0 (en) 1995-10-19
NO954152L (en) 1995-10-18
CZ272995A3 (en) 1996-02-14
JPH08508984A (en) 1996-09-24
PT697881E (en) 2002-10-31
SK283442B6 (en) 2003-07-01
NO954152D0 (en) 1995-10-18
ES2178653T3 (en) 2003-01-01
EP0697881B2 (en) 2009-05-06
NO321076B1 (en) 2006-03-13
JP3862273B2 (en) 2006-12-27

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