FR2872164B1 - Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2872164B1
FR2872164B1 FR0407124A FR0407124A FR2872164B1 FR 2872164 B1 FR2872164 B1 FR 2872164B1 FR 0407124 A FR0407124 A FR 0407124A FR 0407124 A FR0407124 A FR 0407124A FR 2872164 B1 FR2872164 B1 FR 2872164B1
Authority
FR
France
Prior art keywords
quinoline
pharmaceutical compositions
compositions containing
substituted derivatives
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0407124A
Other languages
English (en)
Other versions
FR2872164A1 (fr
Inventor
Michel Tabart
Fabrice Viviani
Serge Mignani
Baptiste Ronan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to FR0407124A priority Critical patent/FR2872164B1/fr
Priority to TW094120002A priority patent/TW200609221A/zh
Priority to JP2007518637A priority patent/JP2008504351A/ja
Priority to EP05784030A priority patent/EP1763527A1/fr
Priority to PCT/FR2005/001598 priority patent/WO2006010831A1/fr
Priority to US11/571,407 priority patent/US20080032985A1/en
Priority to EA200700166A priority patent/EA200700166A1/ru
Priority to AU2005266218A priority patent/AU2005266218A1/en
Priority to CNA2005800219094A priority patent/CN101023076A/zh
Priority to KR1020067027838A priority patent/KR20070029763A/ko
Priority to CA002571668A priority patent/CA2571668A1/fr
Publication of FR2872164A1 publication Critical patent/FR2872164A1/fr
Application granted granted Critical
Publication of FR2872164B1 publication Critical patent/FR2872164B1/fr
Priority to IL179709A priority patent/IL179709A0/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
FR0407124A 2004-06-29 2004-06-29 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related FR2872164B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR0407124A FR2872164B1 (fr) 2004-06-29 2004-06-29 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
TW094120002A TW200609221A (en) 2004-06-29 2005-06-16 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
KR1020067027838A KR20070029763A (ko) 2004-06-29 2005-06-24 4-치환 퀴놀린 유도체, 이의 제조를 위한 방법과 중간체 및이를 함유하는 약학적 조성물
PCT/FR2005/001598 WO2006010831A1 (fr) 2004-06-29 2005-06-24 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US11/571,407 US20080032985A1 (en) 2004-06-29 2005-06-24 4-Substituted Quinoline Derivatives, Method and Intermediates for Their Preparation and Pharmaceutical Compositions Containing Them
EA200700166A EA200700166A1 (ru) 2004-06-29 2005-06-24 4-замещённые производные хинолина, способ получения и промежуточные вещества для их приготовления и содержащие их фармацевтические композиции
JP2007518637A JP2008504351A (ja) 2004-06-29 2005-06-24 ４−置換キノリン誘導体、その製造方法およびそのための中間体、ならびにこれを含む医薬組成物
CNA2005800219094A CN101023076A (zh) 2004-06-29 2005-06-24 4－取代的喹啉衍生物，其制备的方法和中间体，以及含有它们的药物组合物
EP05784030A EP1763527A1 (fr) 2004-06-29 2005-06-24 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
CA002571668A CA2571668A1 (fr) 2004-06-29 2005-06-24 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
AU2005266218A AU2005266218A1 (en) 2004-06-29 2005-06-24 4-substituted quinoline derivatives, method and intermediates for preparing same and pharmaceutical compositions containing same
IL179709A IL179709A0 (en) 2004-06-29 2006-11-29 4-substituted quinoline derivatives, method and intermediates for preparing same and pharmaceutical compositions containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0407124A FR2872164B1 (fr) 2004-06-29 2004-06-29 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2872164A1 FR2872164A1 (fr) 2005-12-30
FR2872164B1 true FR2872164B1 (fr) 2006-11-17

Family

ID=34954685

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0407124A Expired - Fee Related FR2872164B1 (fr) 2004-06-29 2004-06-29 Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (12)

Country Link
US (1) US20080032985A1 (fr)
EP (1) EP1763527A1 (fr)
JP (1) JP2008504351A (fr)
KR (1) KR20070029763A (fr)
CN (1) CN101023076A (fr)
AU (1) AU2005266218A1 (fr)
CA (1) CA2571668A1 (fr)
EA (1) EA200700166A1 (fr)
FR (1) FR2872164B1 (fr)
IL (1) IL179709A0 (fr)
TW (1) TW200609221A (fr)
WO (1) WO2006010831A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1796466A4 (fr) 2004-06-15 2009-09-02 Glaxo Group Ltd Agents antibacteriens
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
US7709483B2 (en) 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (fr) 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
CL2008001003A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CL2008001002A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
DK2137196T3 (da) * 2007-04-20 2011-01-10 Glaxo Group Ltd Tricykliske nitrogenholdige forbindelser som antibakterielle midler
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
JP2011518149A (ja) 2008-04-15 2011-06-23 アクテリオン ファーマシューティカルズ リミテッド 三環式抗菌剤
WO2010043714A1 (fr) 2008-10-17 2010-04-22 Glaxo Group Limited Composés azotés tricycliques utilisés comme agents antibactériens
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
AU2015304847B2 (en) 2014-08-22 2018-10-25 Glaxosmithkline Intellectual Property Development Limited Tricyclic nitrogen containing compounds for treating Neisseria gonorrhoea infection
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053340C (fr) * 1990-10-18 2002-04-02 Timothy P. Burkholder Derives de mercaptoacetylamide utiles comme inhibiteurs de l'encephalinase et de l'ace
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
AU757059B2 (en) * 1997-06-19 2003-01-30 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
WO2000043383A1 (fr) * 1999-01-20 2000-07-27 Smithkline Beecham P.L.C. Piperidinylquinolines utilisees comme inhibiteurs de la proteine tyrosine kinase
JP2004504397A (ja) * 2000-07-26 2004-02-12 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー 抗菌活性を有するアミノピペリジンキノリン類およびそれらのアザイソステリックアナログ類
FR2858619B1 (fr) * 2003-08-08 2006-12-22 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
FR2872164A1 (fr) 2005-12-30
WO2006010831A1 (fr) 2006-02-02
KR20070029763A (ko) 2007-03-14
JP2008504351A (ja) 2008-02-14
AU2005266218A1 (en) 2006-02-02
EP1763527A1 (fr) 2007-03-21
CN101023076A (zh) 2007-08-22
US20080032985A1 (en) 2008-02-07
AU2005266218A2 (en) 2006-02-02
CA2571668A1 (fr) 2006-02-02
EA200700166A1 (ru) 2007-06-29
IL179709A0 (en) 2007-05-15
TW200609221A (en) 2006-03-16

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Legal Events

Date Code Title Description
CA Change of address
TP Transmission of property
ST Notification of lapse

Effective date: 20100226