GB1194790A - Benzenesulphonyl-Ureas and Process for Preparing Them - Google Patents
Benzenesulphonyl-Ureas and Process for Preparing ThemInfo
- Publication number
- GB1194790A GB1194790A GB38468/68A GB3846868A GB1194790A GB 1194790 A GB1194790 A GB 1194790A GB 38468/68 A GB38468/68 A GB 38468/68A GB 3846868 A GB3846868 A GB 3846868A GB 1194790 A GB1194790 A GB 1194790A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- cyclopentyl
- bicyclo
- signifies
- benzenesulphonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,194,790. Benzenesulphonyl-ureas. FARBWERKE HOECHST A.G. 12 Aug., 1968 [10 Aug., 1967], No. 38468/68. Heading C2C. Novel benzenesulphonyl - ureas (including salts thereof) of the general formula wherein R<SP>1</SP> signifies 4,7-endomethylene-perhydroindan-5-yl which may be substituted by chlorine at the 6-position, 4,7-endomethyleneperhydroindan - 2 - yl, 2,6 - endomethylenecycloheptyl, 4,4 - dimethyl #<SP>2</SP> - cyclohexenyl, #<SP>2</SP> - cyclopentenyl, -heptenyl or -octenyl, norcaran-7-yl, bicyclo-[5,1,0]-octyl-(8), bicyclo- [6,10] - nonyl - (9), bicyclo - [4,2,0] - octyl - (7), 2,5 - endo - cyclobutylene - (1,2) - cyclohexyl, methyl - cyclopentyl, 3,3 - dimethyl - cyclopentyl, 3 - ethyl cyclopentyl, 3 - tert. - butylcyclopentyl, 2 - chloro - cyclopentyl, #<SP>2</SP> - cyclopentenyl - methyl, bicyclo - [2,1,1] - hexyl - (2), spiro - (2 - cyclopropane - cyclopentyl), spiro- (2 - cyclobutane - cyclopentyl), spiro - (2 - cyclopentane - cyclopentyl), cyclopropyl, cyclobutyl, 5 - methyl - #<SP>2</SP> - cyclohexenyl, or bicyclo - [3,1,0] - hexyl, X represents (a) a phenyl group carrying at any desired position the substituents Z and Z<SP>1</SP> which may be the same or different and wherein Z signifies hydrogen, halogen, alkyl, alkoxy, alkenoxy, alkoxyalkoxy, phenalkoxy, acyl, benzoyl, CF 3 or OH and Z<SP>1</SP> signifies CN, NO 2 , hydrogen, halogen, alkyl, alkoxy, alkoxy-alkoxy, or OH or (b) a thiophene group which may be substituted by one or two substituents selected from alkyl, alkoxy, alkoxy-alkoxy, alkenoxy, phenalkoxy radicals and halogen atoms, and Y signifies -CH 2 .CH 2 .-, -CH 2 .CH.Me- or -CH.Me.CH 2 - are obtained according to Standard methods. 5 Amino - 4,7 - endomethylene - perhydroindane is prepared by hydrogenating dicyclopentadiene-bis-nitroso-chloride. N - [4 - (# - <2 - Methoxy - 5 - chloro - benzamido> - ethyl) - benzenesulphonyl] - N<SP>1</SP> - (4,7- endomethylene - perhydroindanyl - 5) - isourea methyl ether is obtained by treating the corresponding thiourea with mercury oxide in the presence of methanol and dioxane. Pharmaceutical preparations showing hypoglycaemic activity contain as active ingredient the above novel compounds; administration is, e.g. in the form of a tablet or powder.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0053202 | 1967-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1194790A true GB1194790A (en) | 1970-06-10 |
Family
ID=7106084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB38468/68A Expired GB1194790A (en) | 1967-08-10 | 1968-08-12 | Benzenesulphonyl-Ureas and Process for Preparing Them |
Country Status (21)
| Country | Link |
|---|---|
| AR (4) | AR193338A1 (en) |
| AT (2) | AT321316B (en) |
| CH (5) | CH522615A (en) |
| CY (1) | CY585A (en) |
| DK (1) | DK132946C (en) |
| ES (1) | ES357107A1 (en) |
| FI (1) | FI50115C (en) |
| FR (2) | FR1598160A (en) |
| GB (1) | GB1194790A (en) |
| IL (1) | IL30431A (en) |
| IS (1) | IS767B6 (en) |
| IT (1) | IT1053691B (en) |
| LU (1) | LU56488A1 (en) |
| MC (1) | MC725A1 (en) |
| MY (1) | MY7100109A (en) |
| NL (1) | NL163778C (en) |
| NO (1) | NO126685B (en) |
| OA (1) | OA02877A (en) |
| PL (1) | PL84736B1 (en) |
| SE (1) | SE352345B (en) |
| SU (6) | SU404232A3 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030140A2 (en) * | 1979-11-30 | 1981-06-10 | E.I. Du Pont De Nemours And Company | Processes for preparing herbicidal N-(substituted heterocyclicaminocarbonyl)-aromatic sulfonamides |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791638A (en) * | 1971-11-20 | 1973-05-21 | Hoechst Ag | SULFONYL-UREES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS |
-
1968
- 1968-07-15 AT AT308073A patent/AT321316B/en not_active IP Right Cessation
- 1968-07-15 LU LU56488D patent/LU56488A1/xx unknown
- 1968-07-15 AT AT06800/68A patent/AT319263B/en not_active IP Right Cessation
- 1968-07-16 FI FI682028A patent/FI50115C/en active
- 1968-07-16 CH CH371472A patent/CH522615A/en not_active IP Right Cessation
- 1968-07-16 CH CH33871A patent/CH522609A/en not_active IP Right Cessation
- 1968-07-16 CH CH371372A patent/CH522614A/en not_active IP Right Cessation
- 1968-07-16 CH CH33971A patent/CH522610A/en not_active IP Right Cessation
- 1968-07-16 NO NO02818/68A patent/NO126685B/no unknown
- 1968-07-16 CH CH1062168A patent/CH506500A/en not_active IP Right Cessation
- 1968-07-17 SE SE09781/68A patent/SE352345B/xx unknown
- 1968-07-25 IL IL30431A patent/IL30431A/en unknown
- 1968-08-05 PL PL1968128491A patent/PL84736B1/en unknown
- 1968-08-08 NL NL6811279.A patent/NL163778C/en active
- 1968-08-09 IT IT20028/68A patent/IT1053691B/en active
- 1968-08-09 OA OA53352A patent/OA02877A/en unknown
- 1968-08-09 IS IS1759A patent/IS767B6/en unknown
- 1968-08-09 ES ES357107A patent/ES357107A1/en not_active Expired
- 1968-08-09 DK DK386868A patent/DK132946C/en active
- 1968-08-09 MC MC771A patent/MC725A1/en unknown
- 1968-08-10 SU SU1647219A patent/SU404232A3/ru active
- 1968-08-10 SU SU1615896A patent/SU435610A3/ru active
- 1968-08-10 SU SU1650165A patent/SU399115A3/ru active
- 1968-08-10 SU SU1615146A patent/SU400086A3/ru active
- 1968-08-10 SU SU1647218A patent/SU437277A3/en active
- 1968-08-10 SU SU1615624A patent/SU460622A3/en active
- 1968-08-12 FR FR1598160D patent/FR1598160A/fr not_active Expired
- 1968-08-12 GB GB38468/68A patent/GB1194790A/en not_active Expired
- 1968-11-08 FR FR173083A patent/FR8094M/fr not_active Expired
-
1969
- 1969-12-02 AR AR225658A patent/AR193338A1/en active
- 1969-12-02 AR AR225660A patent/AR193491A1/en active
- 1969-12-02 AR AR225656A patent/AR192552A1/en active
-
1971
- 1971-04-22 CY CY58571A patent/CY585A/en unknown
- 1971-08-13 AR AR237385A patent/AR196978A1/en active
- 1971-12-31 MY MY1971109A patent/MY7100109A/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030140A2 (en) * | 1979-11-30 | 1981-06-10 | E.I. Du Pont De Nemours And Company | Processes for preparing herbicidal N-(substituted heterocyclicaminocarbonyl)-aromatic sulfonamides |
| EP0030140A3 (en) * | 1979-11-30 | 1981-09-02 | E.I. Du Pont De Nemours And Company | Processes for preparing herbicidal n-(substituted heterocyclicaminocarbonyl)-aromatic sulfonamides |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |
