GB1416397A - Process for the preparation of 1-hydroxy-2-pyridones - Google Patents
Process for the preparation of 1-hydroxy-2-pyridonesInfo
- Publication number
- GB1416397A GB1416397A GB1358773A GB1358773A GB1416397A GB 1416397 A GB1416397 A GB 1416397A GB 1358773 A GB1358773 A GB 1358773A GB 1358773 A GB1358773 A GB 1358773A GB 1416397 A GB1416397 A GB 1416397A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- alkyl
- carbon atoms
- hydrogen atom
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1416397 Process for 1-hydroxy-2-pyridones HOECHST AG 21 March 1973 [25 March 1972] 13587/73 Heading C2C The invention comprises making compounds in which R 1 represents an alkyl radical of 1 to 17 carbon atoms which may be branched; an alkenyl radical of 2 to 17 carbon atoms; a cycloalkyl radical of 3 to 8 carbon atoms; a cyclohexylalkyl radical; a phenyl, phenylalkyl, phenylalkenyl, benzhydryl, phenoxymethyl; phenylmercaptomethyl or phenyl-sulphonylmethyl radical which may be substituted in the aromatic nucleus by one or more alkyl, alkoxy, amino, nitro, alkoxycarbonyl or cyano groups or halogen atoms; or a furyl or furylalkenyl radical; R 2 represents a hydrogen atom or an alkyl, alkenyl or alkynyl radical or a benzyl group or R 2 together with R 1 or R 3 forms a 5- or 6- membered carbocyclic ring; R 3 represents a hydrogen atom, an alkyl radical or a phenyl group and R 4 represents a hydrogen atom, an alkyl or alkenyl radical, a methoxymethyl or benzyl radical, or a chlorine or bromine atom, by reacting a 2-pyrone of the general Formula (II) with NH 2 OH or its salt in the presence of an optionally substituted aminopyridine or imidazole. Pharmaceutical preparations showing antibacterial and antimycotic actions contain (I) as active ingredient.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722214608 DE2214608C3 (en) | 1972-03-25 | Process for the preparation of J-hydroxy-2-pyridones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1416397A true GB1416397A (en) | 1975-12-03 |
Family
ID=5840130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1358773A Expired GB1416397A (en) | 1972-03-25 | 1973-03-21 | Process for the preparation of 1-hydroxy-2-pyridones |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS5233B2 (en) |
| KR (1) | KR780000095B1 (en) |
| AR (1) | AR219038A1 (en) |
| AT (1) | AT327190B (en) |
| BE (1) | BE797346A (en) |
| BG (2) | BG22814A3 (en) |
| CA (1) | CA979449A (en) |
| CH (1) | CH579050A5 (en) |
| CS (1) | CS183686B2 (en) |
| DD (1) | DD105612A5 (en) |
| DK (1) | DK139966C (en) |
| EG (1) | EG10850A (en) |
| ES (1) | ES412847A1 (en) |
| FI (1) | FI55331C (en) |
| FR (1) | FR2177963B1 (en) |
| GB (1) | GB1416397A (en) |
| HU (1) | HU166579B (en) |
| MY (1) | MY7800114A (en) |
| NL (1) | NL175177C (en) |
| NO (1) | NO139861C (en) |
| PH (1) | PH9480A (en) |
| PL (1) | PL91738B1 (en) |
| RO (1) | RO62622A (en) |
| SE (1) | SE383151B (en) |
| SU (1) | SU468418A3 (en) |
| YU (1) | YU35583B (en) |
| ZA (1) | ZA732042B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2146990A (en) * | 1983-09-23 | 1985-05-01 | Nat Res Dev | 1-hydroxypyrid-2-ones |
| US4912118A (en) * | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
| USRE34313E (en) * | 1983-09-23 | 1993-07-13 | National Research Development Corporation | Pharmaceutical compositions |
| WO2004078727A1 (en) * | 2003-02-05 | 2004-09-16 | Nippon Soda Co., Ltd. | Novel 6-fluoroalkyl-2(1h)-pyridinones and 6-fluoro- alkylpyridines and processes for the production thereof |
| WO2019228988A1 (en) * | 2018-05-30 | 2019-12-05 | Clariant International Ltd | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| EP4122918A1 (en) * | 2021-07-19 | 2023-01-25 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2024115319A1 (en) * | 2022-11-28 | 2024-06-06 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2024104987A3 (en) * | 2022-11-16 | 2024-06-27 | Clariant International Ltd | Process for the preparation of piroctone, including crystallization or precipitation, piroctone particles and process for the preparation of piroctone olamine |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4178242A (en) * | 1975-11-11 | 1979-12-11 | Anic S.P.A. | Method for the purification of sewage waters which contain organic compounds of an anionic character |
| JPS5323145A (en) * | 1976-07-20 | 1978-03-03 | Kurita Water Ind Ltd | Method of dehydrating sludge |
| JPS54144759A (en) * | 1978-04-29 | 1979-11-12 | Tobata Tekko Kk | Method of decoloring waste water containing dyestuffs |
| US5817825A (en) * | 1994-11-02 | 1998-10-06 | Hoechst Aktiengesellschaft | Process for the preparation of 1-hydroxy-2-pyridones |
-
1973
- 1973-03-11 EG EG86/73A patent/EG10850A/en active
- 1973-03-12 CA CA166,905A patent/CA979449A/en not_active Expired
- 1973-03-20 ES ES412847A patent/ES412847A1/en not_active Expired
- 1973-03-20 NL NLAANVRAGE7303870,A patent/NL175177C/en not_active IP Right Cessation
- 1973-03-21 BG BG025589A patent/BG22814A3/en unknown
- 1973-03-21 BG BG023052A patent/BG22817A3/en unknown
- 1973-03-21 GB GB1358773A patent/GB1416397A/en not_active Expired
- 1973-03-22 FI FI896/73A patent/FI55331C/en active
- 1973-03-22 YU YU784/73A patent/YU35583B/en unknown
- 1973-03-22 PH PH14455*UA patent/PH9480A/en unknown
- 1973-03-22 CH CH420473A patent/CH579050A5/xx not_active IP Right Cessation
- 1973-03-22 KR KR7300464A patent/KR780000095B1/en active
- 1973-03-23 NO NO1205/73A patent/NO139861C/en unknown
- 1973-03-23 HU HUHO1556A patent/HU166579B/hu unknown
- 1973-03-23 JP JP48032786A patent/JPS5233B2/ja not_active Expired
- 1973-03-23 AR AR247210A patent/AR219038A1/en active
- 1973-03-23 ZA ZA732042A patent/ZA732042B/en unknown
- 1973-03-23 SU SU1896821A patent/SU468418A3/en active
- 1973-03-23 SE SE7304111A patent/SE383151B/en unknown
- 1973-03-23 RO RO7300074280A patent/RO62622A/en unknown
- 1973-03-23 AT AT262473A patent/AT327190B/en not_active IP Right Cessation
- 1973-03-23 DK DK162073A patent/DK139966C/en not_active IP Right Cessation
- 1973-03-23 DD DD169759A patent/DD105612A5/xx unknown
- 1973-03-24 PL PL1973161446A patent/PL91738B1/pl unknown
- 1973-03-26 CS CS7300002187A patent/CS183686B2/en unknown
- 1973-03-26 BE BE129278A patent/BE797346A/en not_active IP Right Cessation
- 1973-03-26 FR FR7310713A patent/FR2177963B1/fr not_active Expired
-
1978
- 1978-12-30 MY MY114/78A patent/MY7800114A/en unknown
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2146990A (en) * | 1983-09-23 | 1985-05-01 | Nat Res Dev | 1-hydroxypyrid-2-ones |
| US4587240A (en) * | 1983-09-23 | 1986-05-06 | National Research Development Corp. | Pharmaceutical compositions |
| US4912118A (en) * | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
| US5104865A (en) * | 1983-09-23 | 1992-04-14 | National Research Development Corporation | Iron complexes of hydroxypyridones useful for treating iron overload |
| USRE34313E (en) * | 1983-09-23 | 1993-07-13 | National Research Development Corporation | Pharmaceutical compositions |
| WO2004078727A1 (en) * | 2003-02-05 | 2004-09-16 | Nippon Soda Co., Ltd. | Novel 6-fluoroalkyl-2(1h)-pyridinones and 6-fluoro- alkylpyridines and processes for the production thereof |
| WO2019228988A1 (en) * | 2018-05-30 | 2019-12-05 | Clariant International Ltd | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| CN112351970A (en) * | 2018-05-30 | 2021-02-09 | 科莱恩国际有限公司 | Method for forming 2-hydroxypyridine-1-oxide or derivative thereof |
| US20210214307A1 (en) * | 2018-05-30 | 2021-07-15 | Clariant International Ltd. | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| US11753379B2 (en) * | 2018-05-30 | 2023-09-12 | Clariant International Ltd | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| EP4122918A1 (en) * | 2021-07-19 | 2023-01-25 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2023001781A1 (en) * | 2021-07-19 | 2023-01-26 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2024104987A3 (en) * | 2022-11-16 | 2024-06-27 | Clariant International Ltd | Process for the preparation of piroctone, including crystallization or precipitation, piroctone particles and process for the preparation of piroctone olamine |
| WO2024115319A1 (en) * | 2022-11-28 | 2024-06-06 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1432563A (en) | Platinum- co-ordination compounds | |
| GB1132082A (en) | The manufacture of pyrimidine derivatives | |
| GB1416397A (en) | Process for the preparation of 1-hydroxy-2-pyridones | |
| GB1355631A (en) | Imidazole derivatives | |
| FI811671L (en) | NYA PARASUBTITUERADE 3-FENOXI-1-ALKYLAMINOPROPANOL-2-FOERENINGAR WITH BETA RECEPTOR HAEMMANDE NETWORK | |
| GB1106040A (en) | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof | |
| GB1433701A (en) | 5-6-benzene ring substituted benzimidazole-2-carbamate derivative having anthelmintic activity apparatus | |
| GB1304623A (en) | ||
| GB1142066A (en) | New diphenyl-ureas and process for preparing them | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| GB1256750A (en) | ||
| ES431497A1 (en) | S-triazolo(1,5-a)pyridine derivative | |
| ES374692A1 (en) | 1-substituted-3-(2-pyrimidinyl) imidazolium salts | |
| GB1432816A (en) | Pharmaceutical antimycotic compositions medicaments and method | |
| GB1325386A (en) | Quinazoline derivatives processes for producing them and compositions containing them | |
| GB1206088A (en) | New pyrazolodiazepinone compounds and methods for their production | |
| GB1138315A (en) | 2-amino-benzylamines | |
| GB1433103A (en) | Pharmacologically active pyrrolodiazepines | |
| GB1276061A (en) | Tetronic acid derivatives, process for the manufacture thereof, and compositions containing such compounds | |
| ES357317A1 (en) | N-disubstituted 3-amino-1,2-benzisothiazoles as antimycotic agents | |
| GB1442421A (en) | Propanolamines | |
| GB1392015A (en) | 4-or 5-nitroimidazoles and processes for their manufacture | |
| GB1384523A (en) | Oxime derivatives and their preparation | |
| GB1261594A (en) | Novel 3-arylimino-4,5-dichloro-1,2-dithioles, processes for their production and compositions containing them | |
| GB1237034A (en) | Substituted indolines |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930320 |
