GB617190A - Esters of salicyclic acid - Google Patents
Esters of salicyclic acidInfo
- Publication number
- GB617190A GB617190A GB16248/46A GB1624846A GB617190A GB 617190 A GB617190 A GB 617190A GB 16248/46 A GB16248/46 A GB 16248/46A GB 1624846 A GB1624846 A GB 1624846A GB 617190 A GB617190 A GB 617190A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dimethylpiperidino
- propyl
- prepared
- esterification
- treated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
3 - (21 : 61 - Dimethylpiperidino) - propyl salicylate <FORM:0617190/IV(b)/1> and its acid addition salts are prepared by esterification, e.g. by the reaction preferably in an inert solvent of a salicylyl halide with 3-(21 : 61-dimethylpiperidino)-propyl alcohol or of salicylic acid with a 3-(21 : 61-dimethylpiperidino)-propyl halide, to give in each case the hydrohalide salt which is convertible to the free ester by treatment with alkali. Other salts of the ester may be prepared by treating it with the appropriate acid. The compounds may be used as an thetics. In examples: (1) 3-(21 : 61-dimethylpiperidino)-propyl chloride is treated with salicylic acid in isopropanol to produce 3 - (21 : 61 - dimethylpiperidino) - propyl salicylate hydrochloride, and (2) the product prepared by the method of (1) is treated with aqueous sodium hydroxide to liberate the free base. The Specification as open to inspection under Sect. 91 comprises also the preparation of the products by processes of trans-esterification, condensation and replacement. This subject-matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US617190XA | 1945-06-30 | 1945-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB617190A true GB617190A (en) | 1949-02-02 |
Family
ID=22037662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB16248/46A Expired GB617190A (en) | 1945-06-30 | 1946-05-28 | Esters of salicyclic acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB617190A (en) |
-
1946
- 1946-05-28 GB GB16248/46A patent/GB617190A/en not_active Expired
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