GB951653A - Improvements in or relating to 6-pteridinehydrazide and amidrazone derivatives - Google Patents

Improvements in or relating to 6-pteridinehydrazide and amidrazone derivatives

Info

Publication number
GB951653A
GB951653A GB4001060A GB4001060A GB951653A GB 951653 A GB951653 A GB 951653A GB 4001060 A GB4001060 A GB 4001060A GB 4001060 A GB4001060 A GB 4001060A GB 951653 A GB951653 A GB 951653A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
maximum
cyano
compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4001060A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB4001060A priority Critical patent/GB951653A/en
Publication of GB951653A publication Critical patent/GB951653A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/10Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with an aromatic or hetero-aromatic ring directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention comprises compounds of general formula: <FORM:0951653/C2/1> wherein R1, R2, R4 and R5, which may be th same or different, are each hydrogen or an alkyl radical having a maximum of 4 carbon atoms, Ar is an aromatic radical having not more than 8 carbon atoms and R3 is O or NH (including, when only one of R1 and R2 is alkyl, isomers in which it is attached to the nitrogen atom next to the -CR3- group), together with their pharmaceutically acceptable acid addition salts formed with non-toxic acids; and a process for their preparation by reacting a compound of formula: <FORM:0951653/C2/2> in which X is lower carbalkoxy having a maximum of 5 carbon atoms (when R3 is O) or cyano (when R3 is NH), with a compound R1R2N-NH2, the reaction being carried out at elevated temperatures in the presence of a hydroxylated polar organic solvent having less than 6 carbon atoms when X is lower carbalkoxy and in the presence of a lower alcohol having a maximum of 4 carbon atoms when X is cyano. In examples Ar is phenyl, pyridyl, thienyl and phenyl substituted by methyl, amino, hydroxy, methoxy, chloro, fluoro or trifluoromethyl. Specification 951,655 is referred to.
GB4001060A 1960-11-21 1960-11-21 Improvements in or relating to 6-pteridinehydrazide and amidrazone derivatives Expired GB951653A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4001060A GB951653A (en) 1960-11-21 1960-11-21 Improvements in or relating to 6-pteridinehydrazide and amidrazone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4001060A GB951653A (en) 1960-11-21 1960-11-21 Improvements in or relating to 6-pteridinehydrazide and amidrazone derivatives

Publications (1)

Publication Number Publication Date
GB951653A true GB951653A (en) 1964-03-11

Family

ID=10412706

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4001060A Expired GB951653A (en) 1960-11-21 1960-11-21 Improvements in or relating to 6-pteridinehydrazide and amidrazone derivatives

Country Status (1)

Country Link
GB (1) GB951653A (en)

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