IE35626B1 - Phenylacetohydroxamic acids process for their manufacture and preparations containing them - Google Patents

Phenylacetohydroxamic acids process for their manufacture and preparations containing them

Info

Publication number
IE35626B1
IE35626B1 IE1144/71A IE114471A IE35626B1 IE 35626 B1 IE35626 B1 IE 35626B1 IE 1144/71 A IE1144/71 A IE 1144/71A IE 114471 A IE114471 A IE 114471A IE 35626 B1 IE35626 B1 IE 35626B1
Authority
IE
Ireland
Prior art keywords
phenylacetohydroxamic
formula
acids
manufacture
sept
Prior art date
Application number
IE1144/71A
Other versions
IE35626L (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1341570A external-priority patent/CH550146A/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IE35626L publication Critical patent/IE35626L/en
Publication of IE35626B1 publication Critical patent/IE35626B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1331181 Phenylacetohydroxamic acids CIBA-GEIGY AG 8 Sept 1971 [9 Sept 1970 16 July 1971] 41990/71 Heading C2C [Also in Division A5] Novel compounds of Formula I (in which each of R 1 , R 3 and R 4 is H, F, Cl, Br, C 1-6 alkyl or C 1-6 alkoxy and R 2 is H, F, Cl, Br, CF 3 , C 1-6 alkyl or C 1-6 alkoxy, with the proviso that at least one of R 1 , R 2 and R 3 is other than H) and salts thereof with inorganic bases, are prepared by reacting an amide or ester of an acid of Formula II with hydroxylamine or an acid addition salt thereof in a basic medium, and, if desired converting a resulting salt into the free acid or into another salt. Acids of Formula II and alkali metals salts, methyl, cyanomethyl and p-nitrophenyl esters and amides thereof are also disclosed. [GB1331181A]
IE1144/71A 1970-09-09 1971-09-08 Phenylacetohydroxamic acids process for their manufacture and preparations containing them IE35626B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1341570A CH550146A (en) 1970-09-09 1970-09-09 Substd anilino-phenyl acetylhydroxamic acids - anti-inflammatories , analgesics, antipyretics and uv absorbers in sun-screening
CH1058071 1971-07-16

Publications (2)

Publication Number Publication Date
IE35626L IE35626L (en) 1972-03-09
IE35626B1 true IE35626B1 (en) 1976-03-31

Family

ID=25706940

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1144/71A IE35626B1 (en) 1970-09-09 1971-09-08 Phenylacetohydroxamic acids process for their manufacture and preparations containing them

Country Status (18)

Country Link
JP (1) JPS5544060B1 (en)
AT (1) AT310720B (en)
BE (1) BE772333A (en)
BR (1) BR7105911D0 (en)
CS (1) CS159288B2 (en)
DE (1) DE2144641C3 (en)
DK (1) DK143104C (en)
ES (1) ES394894A1 (en)
FI (1) FI55181C (en)
FR (1) FR2106398B1 (en)
GB (1) GB1331181A (en)
HU (1) HU163847B (en)
IE (1) IE35626B1 (en)
IL (1) IL37678A (en)
NL (1) NL175382C (en)
NO (1) NO134946C (en)
SE (1) SE379755B (en)
SU (1) SU474975A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT72878B (en) * 1980-04-24 1983-03-29 Merck & Co Inc Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents
US6355680B1 (en) * 1996-02-20 2002-03-12 Exocell, Inc. Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
IT1283637B1 (en) * 1996-05-14 1998-04-23 Italfarmaco Spa COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSOPPRESSIVE ACTIVITY
CN102976974B (en) * 2012-12-29 2015-01-21 吉首大学 Phenyl benzyl propionyl-N-methyloxyxamic urease inhibitor and synthesis and use thereof

Also Published As

Publication number Publication date
IL37678A (en) 1974-10-22
NO134946C (en) 1977-01-12
DK143104B (en) 1981-03-30
DE2144641B2 (en) 1980-04-03
NL7112085A (en) 1972-03-13
DE2144641A1 (en) 1972-03-16
FR2106398A1 (en) 1972-05-05
SU474975A3 (en) 1975-06-25
BE772333A (en) 1972-03-08
JPS5544060B1 (en) 1980-11-10
AT310720B (en) 1973-10-10
HU163847B (en) 1973-11-28
FI55181B (en) 1979-02-28
FR2106398B1 (en) 1974-10-18
IE35626L (en) 1972-03-09
DK143104C (en) 1981-11-09
DE2144641C3 (en) 1980-12-04
CS159288B2 (en) 1974-12-27
NL175382B (en) 1984-06-01
SE379755B (en) 1975-10-20
NL175382C (en) 1984-11-01
GB1331181A (en) 1973-09-26
NO134946B (en) 1976-10-04
IL37678A0 (en) 1971-11-29
BR7105911D0 (en) 1973-05-10
ES394894A1 (en) 1974-05-16
FI55181C (en) 1979-06-11

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