IL92915A0 - Certain pyrrolylphenyl-substituted hydroxamic acid derivatives - Google Patents

Certain pyrrolylphenyl-substituted hydroxamic acid derivatives

Info

Publication number
IL92915A0
IL92915A0 IL92915A IL9291589A IL92915A0 IL 92915 A0 IL92915 A0 IL 92915A0 IL 92915 A IL92915 A IL 92915A IL 9291589 A IL9291589 A IL 9291589A IL 92915 A0 IL92915 A0 IL 92915A0
Authority
IL
Israel
Prior art keywords
pyrrolylphenyl
certain
acid derivatives
hydroxamic acid
substituted hydroxamic
Prior art date
Application number
IL92915A
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL92915A0 publication Critical patent/IL92915A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IL92915A 1989-01-05 1989-12-28 Certain pyrrolylphenyl-substituted hydroxamic acid derivatives IL92915A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29390889A 1989-01-05 1989-01-05

Publications (1)

Publication Number Publication Date
IL92915A0 true IL92915A0 (en) 1990-09-17

Family

ID=23131076

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92915A IL92915A0 (en) 1989-01-05 1989-12-28 Certain pyrrolylphenyl-substituted hydroxamic acid derivatives

Country Status (12)

Country Link
EP (1) EP0378991A1 (en)
JP (1) JPH02270861A (en)
KR (1) KR900011724A (en)
AU (1) AU4765090A (en)
CA (1) CA2007085A1 (en)
DD (1) DD291551A5 (en)
FI (1) FI900024A (en)
HU (1) HUT53608A (en)
IL (1) IL92915A0 (en)
NO (1) NO900025L (en)
PT (1) PT92762A (en)
ZA (1) ZA9050B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5140047A (en) * 1991-05-03 1992-08-18 Smithkline Beecham Corporation Lipoxygenase inhibitors
HUT76784A (en) * 1993-11-26 1997-11-28 Pfizer Antiinflammatory isoxazoline compounds and pharmaceutical compositions containing them
EP0749307A1 (en) * 1994-03-09 1996-12-27 Pfizer Inc. Isoxazoline compounds as 5-lipoxygenase inhibitors
US6172057B1 (en) 1997-02-27 2001-01-09 American Cyanamid Company N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
PL335401A1 (en) * 1997-02-27 2000-04-25 American Cyanamid Co N-hydroxy-2-(alkyl, aryl or heteroaryl sulphanyl, sulphinyn of sulphonyl)-3-substituted alkyl, aryl or heteroaryl amides as inhibotors of intercellular substance metaloproteinases
CA2410338A1 (en) * 2000-05-22 2001-11-29 Takeda Chemical Industries, Ltd. Tyrosine phosphatase inhibitors
EP1314721A1 (en) * 2000-08-31 2003-05-28 Wakunaga Pharmaceutical Co., Ltd. Novel propenohydroxamic acid derivatives
WO2005065681A1 (en) * 2003-12-19 2005-07-21 Takeda San Diego, Inc. N- hydroxy-3-(3-(1h-imidazol-2-yl)-phenyl)-acrylamide derivatives and related compounds as histone deacetylase (hdac) inhibitors for the treatment of cancer
CN101360723A (en) 2005-09-16 2009-02-04 武田药品工业株式会社 Process for preparing pyrimidinedione derivatives
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0082109A3 (en) * 1981-10-28 1985-04-17 Ciba-Geigy Ag Substituted 2-hydroxyphenylacetic acids and derivatives of them
FR2551063A1 (en) * 1983-08-22 1985-03-01 Inst Nat Sante Rech Med New 2,5-dimethylpyrroles, process for preparing them and their therapeutic use
IL78157A (en) * 1985-03-16 1989-08-15 Wellcome Found Aryl derivatives,their preparation and pharmaceutical compositions containing them
US4792560A (en) * 1985-04-03 1988-12-20 Rorer Pharmaceutical Corporation Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways
GB8531838D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives

Also Published As

Publication number Publication date
ZA9050B (en) 1990-08-29
CA2007085A1 (en) 1990-07-05
JPH02270861A (en) 1990-11-05
DD291551A5 (en) 1991-07-04
PT92762A (en) 1990-07-31
EP0378991A1 (en) 1990-07-25
KR900011724A (en) 1990-08-02
NO900025D0 (en) 1990-01-04
AU4765090A (en) 1990-07-12
HU900040D0 (en) 1990-03-28
NO900025L (en) 1990-07-06
FI900024A0 (en) 1990-01-03
HUT53608A (en) 1990-11-28
FI900024A (en) 1990-07-06

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