IL94777A - חומצה ציס-)-( -h-1)]-4)2(-טטראזול-5-איל( מתיל(-2-פיפרידינקרבוקסילית, מלחים שלה, תהליך להכנתם ותכשירי רוקחות אנטגוניסטי - Google Patents
חומצה ציס-)-( -h-1)]-4)2(-טטראזול-5-איל( מתיל(-2-פיפרידינקרבוקסילית, מלחים שלה, תהליך להכנתם ותכשירי רוקחות אנטגוניסטיInfo
- Publication number
- IL94777A IL94777A IL9477790A IL9477790A IL94777A IL 94777 A IL94777 A IL 94777A IL 9477790 A IL9477790 A IL 9477790A IL 9477790 A IL9477790 A IL 9477790A IL 94777 A IL94777 A IL 94777A
- Authority
- IL
- Israel
- Prior art keywords
- cis
- compound
- methyl
- amino acid
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/371,568 US4968678A (en) | 1988-02-19 | 1989-06-26 | Tetrazole excitatory amino acid receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL94777A0 IL94777A0 (en) | 1991-04-15 |
| IL94777A true IL94777A (he) | 1994-05-30 |
Family
ID=23464503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9477790A IL94777A (he) | 1989-06-26 | 1990-06-18 | חומצה ציס-)-( -h-1)]-4)2(-טטראזול-5-איל( מתיל(-2-פיפרידינקרבוקסילית, מלחים שלה, תהליך להכנתם ותכשירי רוקחות אנטגוניסטי |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4968678A (he) |
| EP (1) | EP0405834A3 (he) |
| JP (1) | JPH0348679A (he) |
| KR (1) | KR910000703A (he) |
| CN (1) | CN1028024C (he) |
| AU (1) | AU621498B2 (he) |
| CA (1) | CA2019167A1 (he) |
| FI (1) | FI903183A0 (he) |
| HU (1) | HU206339B (he) |
| IE (1) | IE902288A1 (he) |
| IL (1) | IL94777A (he) |
| MX (1) | MX21219A (he) |
| NZ (1) | NZ234109A (he) |
| PH (1) | PH26905A (he) |
| PT (1) | PT94447B (he) |
| RU (2) | RU1833385C (he) |
| ZA (1) | ZA904717B (he) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0330353B1 (en) * | 1988-02-19 | 1993-04-07 | Eli Lilly And Company | Tetrazole excitatory amino acid receptor antagonists |
| US5594007A (en) * | 1991-04-18 | 1997-01-14 | Pfizer Inc. | Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols |
| US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
| US5153196A (en) * | 1991-06-05 | 1992-10-06 | Eli Lilly And Company | Excitatory amino acid receptor antagonists and methods for the use thereof |
| JPH07505648A (ja) * | 1992-04-15 | 1995-06-22 | メルク シヤープ エンド ドーム リミテツド | アザサイクリック化合物 |
| US5192751A (en) * | 1992-07-24 | 1993-03-09 | Eli Lilly And Company | Use of competitive NMDA receptor antagonists in the treatment of urinary incontinence |
| US20040208875A1 (en) | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| ATE311864T1 (de) * | 1993-03-29 | 2005-12-15 | Propan-1,3-disulphonsäure und deren pharmazeutisch akzeptable salze zur behandlung von amyloidosis | |
| ATE183184T1 (de) * | 1994-01-31 | 1999-08-15 | Pfizer | Neuroprotektive chroman verbindungen |
| NZ284852A (en) * | 1994-08-18 | 1998-06-26 | Pfizer | 3-(piperidin-1-yl)-chroman-4,7-diol and 1-(4-hydrophenyl)-2-(piperidin-1-yl) alkanol derivatives; medicaments; used as a neuroprotective agent |
| US5880138A (en) * | 1996-10-01 | 1999-03-09 | Eli Lilly And Company | NMDA receptor selective antagonists |
| JP2006501957A (ja) * | 2002-10-04 | 2006-01-19 | クック ウロロジカル インコーポレイテッド | ワイヤバスケットを備えた硬性摘出器具 |
| US8043303B2 (en) * | 2002-10-04 | 2011-10-25 | Cook Medical Technologies Llc | Handle for interchangeable medical device |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| WO2005084564A1 (en) * | 2004-02-27 | 2005-09-15 | Cook Urological Incorporated | Self-tensioning handle for endoscopic device |
| CN101128421A (zh) | 2004-12-22 | 2008-02-20 | 神经化学（国际）有限公司 | 治疗淀粉样相关疾病用的方法与组合物 |
| TW200716088A (en) | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| US8597303B2 (en) * | 2005-11-03 | 2013-12-03 | Cook Medical Technologies Llc | Articulating basket with simultaneous basket extension or basket retraction |
| US8372886B2 (en) | 2005-12-22 | 2013-02-12 | Kiacta Sarl | Treatment of renal disorders, diabetic nephropathy and dyslipidemias |
| PL3851447T3 (pl) | 2006-10-12 | 2024-03-04 | Bellus Health Inc. | Sposoby, związki, kompozycje i nośniki dostarczające kwas 3-amino-1-propanosulfonowy |
| EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536715A (en) * | 1967-03-24 | 1970-10-27 | Miles Lab | 2-lower alkyl-5-(omega-(4-phenyl-1-piperazinyl) lower alkyl)-2h-tetrazoles |
| CA1248531A (en) * | 1984-04-17 | 1989-01-10 | Jeffrey C. Watkins | 4-substituted piperazine-2-carboxylic acids |
| PH23848A (en) * | 1985-05-24 | 1989-11-23 | Ciba Geigy Ag | Certain phosphonic acids and derivatives |
| US4746653A (en) * | 1986-02-28 | 1988-05-24 | Ciba-Geigy Corporation | Certain hetero phosphonic acid derivatives of 2-piperidine or 2-tetrahydropyridinecarboxylates and esters thereof which are useful for the treatment of disorders responsive to blockade of the NMDA receptor in mammals |
| ES2031927T3 (es) * | 1986-11-21 | 1993-01-01 | Ciba-Geigy Ag | Procedimiento para la obtencion de acidos fosfonicos insaturados y derivados. |
| EP0330353B1 (en) * | 1988-02-19 | 1993-04-07 | Eli Lilly And Company | Tetrazole excitatory amino acid receptor antagonists |
-
1989
- 1989-06-26 US US07/371,568 patent/US4968678A/en not_active Expired - Fee Related
-
1990
- 1990-06-18 ZA ZA904717A patent/ZA904717B/xx unknown
- 1990-06-18 KR KR1019900008930A patent/KR910000703A/ko not_active Application Discontinuation
- 1990-06-18 IL IL9477790A patent/IL94777A/he not_active IP Right Cessation
- 1990-06-18 CA CA002019167A patent/CA2019167A1/en not_active Abandoned
- 1990-06-18 NZ NZ234109A patent/NZ234109A/en unknown
- 1990-06-19 MX MX2121990A patent/MX21219A/es unknown
- 1990-06-20 EP EP19900306753 patent/EP0405834A3/en not_active Ceased
- 1990-06-21 PT PT94447A patent/PT94447B/pt not_active IP Right Cessation
- 1990-06-21 PH PH40711A patent/PH26905A/en unknown
- 1990-06-22 AU AU57808/90A patent/AU621498B2/en not_active Ceased
- 1990-06-25 FI FI903183A patent/FI903183A0/fi not_active Application Discontinuation
- 1990-06-25 IE IE228890A patent/IE902288A1/en unknown
- 1990-06-25 HU HU903976A patent/HU206339B/hu not_active IP Right Cessation
- 1990-06-25 CN CN90103125A patent/CN1028024C/zh not_active Expired - Fee Related
- 1990-06-25 JP JP2166530A patent/JPH0348679A/ja active Pending
- 1990-06-25 RU SU904830299A patent/RU1833385C/ru active
-
1991
- 1991-12-10 RU SU915010214A patent/RU2089546C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| FI903183A0 (fi) | 1990-06-25 |
| IE902288L (en) | 1990-12-26 |
| RU1833385C (ru) | 1993-08-07 |
| ZA904717B (en) | 1992-02-26 |
| IE902288A1 (en) | 1991-01-16 |
| MX21219A (es) | 1993-11-01 |
| HU206339B (en) | 1992-10-28 |
| US4968678A (en) | 1990-11-06 |
| PT94447B (pt) | 1997-02-28 |
| CA2019167A1 (en) | 1990-12-26 |
| IL94777A0 (en) | 1991-04-15 |
| HU903976D0 (en) | 1990-11-28 |
| EP0405834A3 (en) | 1991-12-27 |
| RU2089546C1 (ru) | 1997-09-10 |
| KR910000703A (ko) | 1991-01-30 |
| NZ234109A (en) | 1992-04-28 |
| PT94447A (pt) | 1991-02-08 |
| CN1048385A (zh) | 1991-01-09 |
| AU621498B2 (en) | 1992-03-12 |
| EP0405834A2 (en) | 1991-01-02 |
| CN1028024C (zh) | 1995-03-29 |
| PH26905A (en) | 1992-12-03 |
| JPH0348679A (ja) | 1991-03-01 |
| HUT54364A (en) | 1991-02-28 |
| AU5780890A (en) | 1991-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void |
