JP2665344B2 - Denture cleaner - Google Patents

Description

Description: TECHNICAL FIELD The present invention relates to an emulsifying denture cleaner using a fatty acid ester as a solubilizer.

[Prior Art] Dentures adhere to food residue or, in the case of smokers, tobacco. These cause bad breath and are not preferable in oral hygiene. In addition, when a denture stabilizer is used to stabilize the mounting of dentures, a part of the denture stabilizer may adhere to the dentures and remain on the denture when the denture is attached or detached.
Leaving this unsanitary is unsanitary and gives the user discomfort. Denture cleansers have been devised to remove such food residue, tobacco residue, and residue of denture stabilizer (hereinafter referred to as residue, etc.). Such detergents are in the form of effervescent tablets or gels which dissolve before use. In addition to acids, talc, etc., anionic surfactants, nonionic surfactants, sucrose esters (JP-A-61-289025), and Sodium carboxymethylcellulose (JP-A-60-1166)
No. 25) is known.

[Problems to be Solved by the Invention] Conventional detergents can remove water-soluble residues and the like, but oil-soluble residues and the like, such as wax contained in cigarettes or denture stabilizers, oil-based residues, etc. It was difficult to remove food residues. In addition, if a strong abrasive is used to remove hard-to-fall residues, the denture base and the denture itself may be damaged.

SUMMARY OF THE INVENTION An object of the present invention is to provide a denture dissolving detergent capable of easily and quickly removing residues or the like adhered to a denture regardless of whether it is water-soluble or oil-soluble, and an abrasive which does not damage the denture base and the denture itself. .

[Means for Solving the Problems] In the present invention, 5-35% by weight of an ester of a middle or higher fatty acid and a monohydric or dihydric alcohol is mixed with 1-10% by weight of an anionic surfactant and 2-10% by weight of a nonionic surfactant. The present invention provides a denture cleaner prepared by mixing and emulsifying with 1% by weight of cellulose, 1-5% by weight of cellulose or a derivative thereof and purified water.

The ester of a middle or higher fatty acid and a monohydric or dihydric alcohol used in the present invention preferably has 6 to 2 carbon atoms.
0, more preferably 6-16, most preferably 6-1
Fatty acid esters of fatty acids in the range of 4 with monohydric or dihydric alcohols in the range of 1-20, more preferably 2-12, most preferably 3-8 carbon atoms. According to the invention, such fatty acid esters have been found to be particularly good. Specific examples include methyl caprylate, methyl laurate, isopropyl myristate, isopropyl palmitate, cetyl isooctanoate, diisopropyl adipate, diethyl sebacate, stearyl stearate, eicosan arachidinate and the like. Especially, isopropyl myristate and diisopropyl adipate are preferable. The above fatty acid ester is usually 4-39
% By weight, preferably 5-35% by weight, more preferably
Use 10-25% by weight.

The anionic surfactant used in the present invention is a surfactant charged to an anion. For example, sodium sulfate lauryl sulfate, triethanolamine lauryl sulfate, sodium cetyl sulfate or sodium lauroyl sarcosine, which is an alkyl sulfate, is used. -Sodium ethylhexyl sulfosuccinate, sodium lauryl phosphate, alkyl benzene sulfonate, α-olefin sulfonate and the like. 0.5-11% by weight of anionic surfactant,
Preferably 1-10% by weight, more preferably 3-8% by weight is used.

The nonionic surfactant used in the present invention is a surfactant containing a molecule that does not ionize in an aqueous solution, for example, polyoxyethylene nonyl phenyl ether,
Polyoxyethylene octyl phenyl ether, hexaglycerin monooleate, polyoxyethylene polyoxypropylene copolymer, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene cetyl ether, sucrose fatty acid ester and the like are included. The nonionic surfactant is usually used in an amount of 2 to 11% by weight, preferably 2 to 10% by weight, and more preferably 3 to 8% by weight.

The cellulose and derivatives thereof of the present invention include ethers, esters, amino derivatives and halogen derivatives of cellulose. The ether includes an alkyl (preferably lower alkyl) ether, and the alkyl may be substituted with hydroxy, carboxy, methoxy, etc., and a lower alkyl ether such as methylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, sodium carboxymethylcellulose and the like. Is preferred. Examples of the ester include cellulose sulfate and cellulose phosphate, the amino derivative includes aminodeoxycellulose, and the halogen derivative includes chlorodeoxycellulose. Cellulose and its derivatives are usually 0.5-7.5
% By weight, preferably 1-5% by weight, more preferably 2% by weight.
Use -4% by weight.

In the present invention, in addition to the above essential components, an abrasive (for example, hydrated silicon dioxide, synthetic aluminum silicate (light), magnesium carbonate, bentonite or magnesium hydroxide) is usually used in an amount of 1 to 24% by weight, preferably Can be contained in an amount of 1-20% by weight, more preferably 1-15% by weight. As the hydrous silicon dioxide, those commercially available under the trade name Carplex (manufactured by Shionogi & Co., Ltd.) are suitable.

The above fatty acid ester, anionic surfactant, nonionic surfactant, cellulose or a derivative thereof and water are mixed and emulsified by a usual method to prepare a preparation. At this time, if necessary, a bactericide, for example, ethacridine, benzethonium chloride, a humectant, for example, propylene glycol, polyethylene glycol 400, sorbitol, a fragrance, and a coloring agent can be added. Further, as an abrasive, hydrous silicon dioxide can be added to obtain a denture cleaning agent having an abrasive action.

 The preparation of a preferred formulation is as follows.

Cellulose or a derivative thereof is added to a gel obtained by adding a viscous agent to purified water to obtain a uniform gel. Separately, a liquid obtained by adding a nonionic surfactant to a fatty acid ester is gradually added to the above-mentioned gel-like substance, and an anionic surfactant is added to and dissolved in an emulsion obtained. Predetermined bactericides, coloring agents, and fragrances are added, and water-containing silicon dioxide is dispersed. If necessary, purified water is added. In the present invention, it is preferable that the denture is cleaned and used, for example, by rubbing the denture by attaching it to a toothbrush.

[Effects] Since the denture cleaning agent of the present invention contains an oil component, this component dissolves tobacco and a residue of the denture stabilizer and the like. Therefore, the oil-soluble dirt, which has been considered to be difficult to remove, falls off well. In addition, since it contains an anionic surfactant, water-soluble dirt is well removed. In addition, since it is an emulsion, it can be formulated into a cream, and a product which is difficult to be scattered when used is obtained. Further, those containing water-containing silicon dioxide have the effect of polishing without damaging. Therefore,
It has the advantage of polishing dentures and physically removing dirt without damaging the denture base or the denture itself.

EXAMPLES The present invention will be described in more detail with reference to the following Examples,
The effects of the present invention will be clarified by test examples.

Example 1. Preparation method of preparation (preparation for 1 kg) <1> 400 g of purified water is placed in a closed container equipped with an appropriate homogenizer, and 30 g of synthetic sodium / magnesium sodium silicate is added under light stirring to make the mixture uniform. After dispersion, the mixture is vigorously stirred to obtain a transparent gel. 30 g of propylene glycol and 25 g of hydroxypropylcellulose are added to the gel, and the mixture is weakly stirred until a uniform gel is obtained.

<2> 200 g of isopropyl myristate in another suitable container
And polyoxyethylene nonyl phenyl ether 47
g, stir until a homogeneous clear liquid is obtained and warm to 75 ° C.

<3> Warm <1> to 75 ° C., gradually add <2> to emulsify, and then add 50 g of sodium lauryl sulfate with stirring to dissolve.

<4><3> is cooled to 30 ° C. or lower, and a predetermined amount of an aqueous solution of a flavor, a colorant and ethanol is added under stirring, and 50 g of water-containing silicon dioxide is gradually added and dispersed. If necessary, purified water is added. In addition, adjust the liquid volume to obtain 1Kg of denture cleanser.

Example 2. Examples and evaluation In the preparation prepared in accordance with Example 1, the denture cleaning agent or denture polishing agent obtained by changing the type and blending amount of each component was used as a detergency and appearance according to the following criteria. ,
The consistency and the denture base wound were evaluated.

(1) Evaluation method for cleaning power of denture cleaning agent Sample preparation method a. Sample adhered to tobacco and put a stopper 6 with a tube 4 inserted into the opening of a glass bottle 2 provided with a branch 5 as shown in FIG. A transparent acrylic resin plate 1 (25 mm × 65 mm, 2 mm thick) 3 made of the same material as the denture base, using a device which puts the tobacco 3 on the tube 4 and sucks it under reduced pressure from the branch 5.
Each time, a sample corresponding to 5 cigarettes is attached to a sheet of cigarette and dried at 80 ° C. for 4 hours.

b. Denture stabilizer residue sample Four commercially available denture stabilizers (Touch Correct) are sandwiched between the ^two acrylic plates, and the stabilizer is fixed to the acrylic plate under a pressure of about 1 kg / cm ² , washed with water, and water-soluble. Except for the above, an acrylic plate remaining mainly composed of wax and dried at 80 ° C. for 4 hours is used as a sample.

Cleaning method Apply about 1 g of this agent to a toothbrush wetted with water in advance,
The sample is polished for 1 minute, washed with water and dried at 80 ° C. for 4 hours.

<1> Examination of anionic surfactant Determination of the amount of surfactant The composition of a sample containing sodium lauryl sulfate (SLS) is shown below. Good results were obtained with the SLS compounding amount of 1-10%.

Types of anionic surfactants The following types of anionic surfactants were blended, and good results were obtained.

With respect to the emulsifiability, no particular problem was observed when the content was 5%.

<2> Study on Nonionic Surfactant Amount of Nonionic Surfactant The composition in which the blending amount of polyoxyethylene nonylphenyl ether was changed is shown below, and good results were shown when the blending amount was 2 to 10%.

Formulation consistency: The spread diameter at room temperature was measured using a parallel plate viscometer as an indicator of consistency. The relationship between spreading diameter and consistency is as follows.

Spreading diameter 55mm or more Soft Spreading diameter 35-45mm Suitable Spreading diameter 25mm or less Hard The value between the above numerical values is expressed with "Slightly".

Types of Nonionic Surfactants The following types of nonionic surfactants were blended, and good results were obtained.

With respect to the emulsifiability, no particular problem was observed when the content was 5%.

<3> Examination of Cellulose Amount of Cellulose The composition in which the amount of hydroxypropylcellulose was changed is shown below. If the amount is less than 1%, the consistency is slightly lower,
At 5% or more, the consistency of the preparation is slightly high, but preparation is possible.

Types of Cellulose Cellulose was subjected to a mixing experiment for the following types having high water solubility, and good results were obtained in all cases. With respect to the emulsifying property, no particular problem was observed when the content was 2-3%.

<4> Formulation of Hydrous Silicon Dioxide The composition of various abrasives is shown below.
Silicon oxide has the characteristic that it hardly damages the denture base.

Detergency test The composition in which the content of hydrous silicon dioxide was varied is shown below. When the content is less than 1%, the detergency is reduced, and when it is more than 20%, the consistency is significantly increased.

<5> Study on Fatty Acid Esters Fatty Acid Ester Blending Compositions with different blending amounts of isopropyl myristate are shown below. Good results were shown with blending amounts of 5% to 35%.

Selection of Fatty Acid Ester Compositions in which the type of fatty acid ester was changed are shown below, and all showed good detergency.

<6> Comparison with commercially available denture cleaners This product, water, effervescent tablets and gels of commercially available denture cleaners are washed and evaluated by the following washing method and detergency evaluation method, and visual inspection of denture base scratches after washing. It was determined by

Washing method (i) Effervescent tablet Add 25 ml of water to one effervescent tablet, and add 25
Soak at 24 ° C for 24 hours and dry at 80 ° C for 4 hours.

(Ii) This agent, water and gel agent About 1 g of this agent and gel agent (in the case of water) is attached to a toothbrush wetted with water in advance, the sample is polished for 1 minute, then washed with water and dried at 80 ° C for 4 hours. .

Detergency Evaluation Method For the untreated acrylic plate, before and after cleaning when the light intensity at 600 nm is 100, the light intensity is TB and TA, respectively, and the detergency (WP) is evaluated using the following formula when the light intensity is TB and TA, respectively. .

WP (%) − {1− (100−TA) / (100−TB)} × 100 Example 3 The present invention includes the following embodiments.

: 1 to 10% by weight of anionic surfactant, 2 to 10% by weight of nonionic surfactant, 1 to 5% by weight of cellulose or its derivative and fatty acid ester 5 to the total weight of the preparation
If necessary, 35% by weight is dispersed in an aqueous solvent together with an appropriate amount of a bactericide, a humectant, a fragrance, a coloring agent and the like to prepare an emulsified denture cleaner.

: The hydrous silicon dioxide was added 1-based on the total weight of the preparation.
Emulsion type denture cleaning agent is prepared by adding 20% by weight.

: Or preparing an emulsified denture cleaner in which the anionic surfactant is sodium lauryl sulfate and the nonionic surfactant is polyoxyethylene nonylphenyl ether.

: Or preparing an emulsified denture cleaner in which the cellulose or derivative thereof is hydroxypropylcellulose and the fatty acid ester is isopropyl myristate or isopropyl adipate or a mixture thereof.

[Brief description of the drawings]

FIG. 1 is a perspective view of an apparatus for preparing a sample attached to a cigarette. In FIG. 1, 1 ... a transparent acrylic resin plate 2 ... a glass bottle 3 ... a cigarette 4 ... a tube 5 ... a branch 6 ... a stopper

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Masayoshi Yoshimura 95 Takako, Kawachinagano City, Osaka Prefecture (72) Takeo Fujitani 1-28-7 Nishiyamadai, Osaka Sayama City, Osaka Prefecture (72) Inventor Nizo Sugie Tokyo Hachioji City Mejirodai 4-26-10

Claims (2)

(57) [Claims] 1. An ester of 5-35% by weight of an intermediate or higher fatty acid and a monohydric or dihydric alcohol with 1-10% by weight of an anionic surfactant 2-10% by weight of a nonionic surfactant 1-% by weight of cellulose or a derivative thereof A denture cleaner that is emulsified by mixing with 5% by weight and purified water. 2. The denture cleaning composition according to claim 1, further comprising hydrated silicon dioxide.