NO834633L - 1-CYCLEOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7- (4- (OXOALKYL) -1-PIPERAZINYL) -3-QUINOLINCARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND THEIR PREPARATION AND THEIR PREPARATION - Google Patents

1-CYCLEOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7- (4- (OXOALKYL) -1-PIPERAZINYL) -3-QUINOLINCARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND THEIR PREPARATION AND THEIR PREPARATION

Info

Publication number
NO834633L
NO834633L NO834633A NO834633A NO834633L NO 834633 L NO834633 L NO 834633L NO 834633 A NO834633 A NO 834633A NO 834633 A NO834633 A NO 834633A NO 834633 L NO834633 L NO 834633L
Authority
NO
Norway
Prior art keywords
preparation
oxo
piperazinyl
dihydro
fluoro
Prior art date
Application number
NO834633A
Other languages
Norwegian (no)
Other versions
NO161492C (en
NO161492B (en
Inventor
Uwe Petersen
Klaus Grohe
Hans-Joachim Zeiler
Karl Georg Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO834633L publication Critical patent/NO834633L/en
Publication of NO161492B publication Critical patent/NO161492B/en
Publication of NO161492C publication Critical patent/NO161492C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Fodder In General (AREA)

Abstract

The invention relates to 1-cyclopropyl-6-fluoro-1,4 dihydro-4-oxo-7-[4-(oxo-(alkyl)-1-piperazinyl]-quinoline-3-carboxylic acids of Formula (I), processes for their manufacture, compositions containing them and use of said compounds and compositions as antibacterial and/or feedstuff additives.
NO834633A 1982-12-29 1983-12-15 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OKSO-7- (4- (OCSOALKYL) -1-PIPERAZINYL) -3-CHINOLINE CARBOXYLIC ACID. NO161492C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823248505 DE3248505A1 (en) 1982-12-29 1982-12-29 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7 (4- (OXOALKYL) -1-PIPERAZINYL / -3-QUINOLINE CARBONIC ACIDS AND THEIR DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR CONTAINERS

Publications (3)

Publication Number Publication Date
NO834633L true NO834633L (en) 1984-07-02
NO161492B NO161492B (en) 1989-05-16
NO161492C NO161492C (en) 1989-08-23

Family

ID=6182077

Family Applications (1)

Application Number Title Priority Date Filing Date
NO834633A NO161492C (en) 1982-12-29 1983-12-15 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OKSO-7- (4- (OCSOALKYL) -1-PIPERAZINYL) -3-CHINOLINE CARBOXYLIC ACID.

Country Status (20)

Country Link
US (1) US4547503A (en)
EP (1) EP0113092B1 (en)
JP (1) JPS59172471A (en)
KR (1) KR870000896B1 (en)
AT (1) ATE19876T1 (en)
AU (1) AU559519B2 (en)
CA (1) CA1218069A (en)
DD (1) DD216015A5 (en)
DE (2) DE3248505A1 (en)
DK (1) DK159106C (en)
ES (1) ES8500262A1 (en)
FI (1) FI79311C (en)
GR (1) GR79446B (en)
HU (1) HU192861B (en)
IE (1) IE56511B1 (en)
IL (1) IL70538A (en)
NO (1) NO161492C (en)
NZ (1) NZ206706A (en)
PH (5) PH20489A (en)
ZA (1) ZA839645B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3306772A1 (en) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen CHINOLONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3426482A1 (en) * 1984-07-18 1986-01-30 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING HALOGENATED AROYLESSE ESTERS
DE3435392A1 (en) * 1984-09-27 1986-04-03 Bayer Ag, 5090 Leverkusen METHOD FOR THE PRODUCTION OF 2,4-DICHLOR-5-FLUOR-BENZOESAEEURE
JPS6259263A (en) * 1985-09-10 1987-03-14 Kyorin Pharmaceut Co Ltd Quinolonecarboxylic acid derivative
DE3542002A1 (en) * 1985-11-28 1987-06-04 Bayer Ag 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7- (1-PIPERAZINYL) -3-QUINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERIAL AGENTS CONTAINING THEM
US4767762A (en) * 1985-12-23 1988-08-30 Abbott Laboratories Tricyclic quinoline and naphthyride antibacterials
JPS62192321A (en) * 1986-02-19 1987-08-22 Bayer Japan Kk Antimicrobial agent for fish
DE3705621C2 (en) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclic substituted quinolonecarboxylic acid derivatives
ES2006977A6 (en) * 1988-06-13 1989-05-16 Union Quimico Farma Ciprofloxacine bactericide prepn.
FR2657895A1 (en) * 1990-02-05 1991-08-09 Inst Textile De France ANTISEPTIC MATERIAL WITH METALLIC ION COMPLEX GRAFT AND PROCESS FOR PREPARING THE SAME.
TW584632B (en) * 2000-01-12 2004-04-21 Pharmaceutical Ind Tech & Dev 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions
JP2004518677A (en) 2000-12-21 2004-06-24 ファルマシア・アンド・アップジョン・カンパニー Antibacterial quinolone derivatives and their use to treat bacterial infections
KR100821894B1 (en) * 2004-07-02 2008-04-16 주식회사 코오롱 Antibacterial dyes and antibacterial fibers using the same
EP2957561A1 (en) 2014-06-18 2015-12-23 Université Paris 6 Pierre et Marie Curie UPMC Novel fluoroquinolones and use thereof to treat bacterial infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3149104A (en) * 1961-01-03 1964-09-15 Sterling Drug Inc 4-hydroxy-7-styryl-1, 8-naphthyridine-3-carboxylic acids and esters
DE2808070A1 (en) * 1978-02-24 1979-08-30 Bayer Ag PROCESS FOR THE PRODUCTION OF 4-PYRIDONE-3-CARBONIC ACIDS AND / OR DERIVATIVES
JPS5845426B2 (en) * 1978-09-29 1983-10-08 杏林製薬株式会社 Substituted quinoline carboxylic acid derivatives
DE3033157A1 (en) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3142854A1 (en) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-CHINOLINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS

Also Published As

Publication number Publication date
EP0113092A1 (en) 1984-07-11
DK603983D0 (en) 1983-12-28
IL70538A0 (en) 1984-03-30
JPS59172471A (en) 1984-09-29
DE3363607D1 (en) 1986-06-26
JPH0430392B2 (en) 1992-05-21
FI79311C (en) 1989-12-11
KR840006989A (en) 1984-12-04
IL70538A (en) 1987-02-27
DK159106B (en) 1990-09-03
IE56511B1 (en) 1991-08-28
KR870000896B1 (en) 1987-05-02
AU2250983A (en) 1984-07-05
DK603983A (en) 1984-06-30
IE833035L (en) 1984-06-29
ATE19876T1 (en) 1986-06-15
FI834807A0 (en) 1983-12-27
DD216015A5 (en) 1984-11-28
NO161492C (en) 1989-08-23
PH20489A (en) 1987-01-16
PH23670A (en) 1989-09-27
GR79446B (en) 1984-10-30
PH22886A (en) 1989-01-19
HU192861B (en) 1987-07-28
ZA839645B (en) 1984-08-29
ES528496A0 (en) 1984-10-01
DE3248505A1 (en) 1984-07-05
AU559519B2 (en) 1987-03-12
FI79311B (en) 1989-08-31
FI834807A (en) 1984-06-30
PH22496A (en) 1988-09-12
DK159106C (en) 1991-02-25
ES8500262A1 (en) 1984-10-01
NZ206706A (en) 1986-04-11
CA1218069A (en) 1987-02-17
EP0113092B1 (en) 1986-05-21
US4547503A (en) 1985-10-15
PH23141A (en) 1989-05-11
NO161492B (en) 1989-05-16

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