PT89214A - Processo para a preparacao de novos derivados de aminoacidos ciclicos e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados de aminoacidos ciclicos e de composicoes farmaceuticas que os contem

Info

Publication number
PT89214A
PT89214A PT89214A PT8921488A PT89214A PT 89214 A PT89214 A PT 89214A PT 89214 A PT89214 A PT 89214A PT 8921488 A PT8921488 A PT 8921488A PT 89214 A PT89214 A PT 89214A
Authority
PT
Portugal
Prior art keywords
aminosaccharides
polycyclic
preparation
pharmaceutical compositions
same
Prior art date
Application number
PT89214A
Other languages
English (en)
Other versions
PT89214B (pt
Inventor
Rainer Henning
Franz Hock
Hansjorg Urbach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT89214A publication Critical patent/PT89214A/pt
Publication of PT89214B publication Critical patent/PT89214B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54Spiro-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/724,7-Endo-alkylene-iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PT89214A 1987-12-15 1988-12-14 Processo para a preparacao de novos derivados de aminoacidos ciclicos e de composicoes farmaceuticas que os contem PT89214B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873742431 DE3742431A1 (de) 1987-12-15 1987-12-15 Neue derivate cyclischer aminosaeuren, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung

Publications (2)

Publication Number Publication Date
PT89214A true PT89214A (pt) 1989-12-29
PT89214B PT89214B (pt) 1993-07-30

Family

ID=6342621

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89214A PT89214B (pt) 1987-12-15 1988-12-14 Processo para a preparacao de novos derivados de aminoacidos ciclicos e de composicoes farmaceuticas que os contem

Country Status (15)

Country Link
US (1) US4983623A (pt)
EP (1) EP0320753A3 (pt)
JP (1) JPH01197468A (pt)
KR (1) KR890009910A (pt)
AU (1) AU620576B2 (pt)
DE (1) DE3742431A1 (pt)
DK (1) DK695388A (pt)
FI (1) FI885766A (pt)
HU (1) HU203251B (pt)
IL (1) IL88668A0 (pt)
NO (1) NO885552L (pt)
NZ (1) NZ227297A (pt)
PH (1) PH26463A (pt)
PT (1) PT89214B (pt)
ZA (1) ZA889306B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5212191A (en) * 1988-04-08 1993-05-18 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds
US5053414A (en) * 1988-04-08 1991-10-01 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
FR2681864B1 (fr) * 1991-09-27 1995-03-31 Adir Nouveaux derives bicycliques azotes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2703050B1 (fr) * 1993-03-24 1995-04-28 Adir Nouveaux dérivés bicycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO1995003277A1 (fr) * 1993-07-23 1995-02-02 Zaidan Hojin Biseibutsu Kagaku Kenkyukai Nouveau derive de pyrrolidine
WO1995003278A1 (fr) * 1993-07-26 1995-02-02 Zaidan Hojin Biseibutsu Kagaku Kenkyukai Derive de pyrrolidine ou sel de celui-ci pharmaceutiquement acceptable
DE19616509A1 (de) * 1996-04-25 1998-01-15 Asta Medica Ag Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva
US9115082B2 (en) * 2012-01-18 2015-08-25 Catherine Yang Dipeptidyl-peptidase-IV inhibitors for treatment of type 2 diabetes complex with hypertension

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4584285A (en) * 1983-06-02 1986-04-22 Schering Corporation Antihypertensive agents
JPH0651677B2 (ja) * 1985-12-23 1994-07-06 サントリー株式会社 ジペプチド誘導体及びその製法並びに用途
CA1320734C (en) * 1986-02-04 1993-07-27 Suntory Limited Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same
DE3712364A1 (de) * 1987-04-11 1988-10-27 Hoechst Ag Neue pyrrolidin-2-(1,3-dicarbonyl)-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung
DE3712363A1 (de) * 1987-04-11 1988-10-27 Hoechst Ag Neue pyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung
DE3712365A1 (de) * 1987-04-11 1988-10-27 Hoechst Ag Neue 2-acylpyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung

Also Published As

Publication number Publication date
AU620576B2 (en) 1992-02-20
HUT49630A (en) 1989-10-30
NO885552L (no) 1989-06-16
DK695388A (da) 1989-06-16
FI885766A0 (fi) 1988-12-13
IL88668A0 (en) 1989-07-31
HU203251B (en) 1991-06-28
DK695388D0 (da) 1988-12-14
PT89214B (pt) 1993-07-30
EP0320753A3 (de) 1990-12-12
KR890009910A (ko) 1989-08-04
PH26463A (en) 1992-07-27
FI885766A (fi) 1989-06-16
AU2687188A (en) 1989-06-15
ZA889306B (en) 1989-09-27
NO885552D0 (no) 1988-12-14
US4983623A (en) 1991-01-08
EP0320753A2 (de) 1989-06-21
DE3742431A1 (de) 1989-07-13
JPH01197468A (ja) 1989-08-09
NZ227297A (en) 1992-01-29

Similar Documents

Publication Publication Date Title
PT89094A (pt) Processo para a preparacao de 1-aril-3-quinolina-e 1-aril-3-isoquinolina-carboxamidas e de composicoes farmaceuticas que as contem
PT84449B (pt) Processo para a preparacao de novos derivados 3,5-dissubstituidos do pirocatecol e de composicoes farmaceuticas que os contem
PT89661A (pt) Processo para a preparacao de compostos pirrolicos substituidos e de composicoes farmaceuticas que os contem
PT84277B (pt) Processo para a preparacao de derivados de indolizina e de composicoes que os contem
PT89405B (pt) Processo para a preparacao de derivados de isoquinolina e de composicoes farmaceuticas que os contem
PT97114A (pt) Processo para a preparacao de derivados de hidantoina e de composicoes farmaceuticas que os contem
PT84681B (pt) Processo para a preparacao de carboxamidas heterociclicas e de composicoes farmaceuticas que as contem
PT84187B (pt) Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem
PT99795A (pt) Processo para a preparacao e novos derivados de piperidinil-benzimidazol e de composicoes farmaceuticas que os contem
PT80363B (pt) Processo para a preparacao de derivados de fenol e de composicoes farmaceuticas que os contem
PT84462B (pt) Rocesso para a preparacao de novos tiazois e oxazois substituidos e de composicoes farmaceuticas que os contem
PT83558B (pt) Processo para a preparacao de derivados da carboxamida e de composicoes farmaceuticas que os contem
PT91870A (pt) Processo para apreparacao de novas quinoliloxazol-2-onas e de composicoes farmaceuticas que as contem
PT81502B (pt) Processo para a preparacao de derivados de colecalciferol e de composicoes farmaceuticas que os contem
PT90172A (pt) Processo para a preparacao de n-benzopiranillactames insaturados e de composicoes farmaceuticas que os contem
PT83604B (pt) Processo para a preparacao de derivados da flavona e de composicoes farmaceuticas que os contem
PT81431B (pt) Processo para a preparacao de derivados de piridina triciclicos e de composicoes farmaceuticas que os contem
PT89145A (pt) Processo para a preparacao de derivados da manumicina e de composicoes farmaceuticas que os contem
PT89311A (pt) Processo para a preparacao de novos aminoalcoxi-p-benzonitrilos substituidos utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem
PT89214A (pt) Processo para a preparacao de novos derivados de aminoacidos ciclicos e de composicoes farmaceuticas que os contem
PT88351A (pt) Processo para a preparacao de derivados de isoxazol-beta-carbolina e de composicoes farmaceuticas que os contem
PT90864A (pt) Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem
PT91979A (pt) Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem
PT90904A (pt) Processo para a preparacao de derivados de 3-oxo-propanonitrilo triciclicos e de composicoes farmaceuticas que os contem
PT82440B (pt) Processo para a preparacao de eteres ciclopentilicos e de composicoes farmaceuticas que os contem

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930107

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940731