RO78908A - Procedeu de preparare a unor alfa-6-desoxi-5-hidroxi-tetraciclinei - Google Patents

Procedeu de preparare a unor alfa-6-desoxi-5-hidroxi-tetraciclinei

Info

Publication number
RO78908A
RO78908A RO7478493A RO7849374A RO78908A RO 78908 A RO78908 A RO 78908A RO 7478493 A RO7478493 A RO 7478493A RO 7849374 A RO7849374 A RO 7849374A RO 78908 A RO78908 A RO 78908A
Authority
RO
Romania
Prior art keywords
desoxy
tetracycline
alpha
hydroxy
preparation
Prior art date
Application number
RO7478493A
Other languages
English (en)
French (fr)
Inventor
Thomas A Morris
Original Assignee
Pfizer Inc,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26997777&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO78908(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc,Us filed Critical Pfizer Inc,Us
Publication of RO78908A publication Critical patent/RO78908A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
RO7478493A 1973-04-20 1974-04-19 Procedeu de preparare a unor alfa-6-desoxi-5-hidroxi-tetraciclinei RO78908A (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35308473A 1973-04-20 1973-04-20
US05/421,206 US3954862A (en) 1973-04-20 1973-12-03 Process for producing α-6-deoxytetracyclines

Publications (1)

Publication Number Publication Date
RO78908A true RO78908A (ro) 1982-08-17

Family

ID=26997777

Family Applications (2)

Application Number Title Priority Date Filing Date
RO74102560A RO80170A (ro) 1973-04-20 1974-04-19 Procedeu pentru prepararea 6-desoxitetraciclinelor
RO7478493A RO78908A (ro) 1973-04-20 1974-04-19 Procedeu de preparare a unor alfa-6-desoxi-5-hidroxi-tetraciclinei

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RO74102560A RO80170A (ro) 1973-04-20 1974-04-19 Procedeu pentru prepararea 6-desoxitetraciclinelor

Country Status (30)

Country Link
US (1) US3954862A (ro)
JP (1) JPS5710863B2 (ro)
AR (1) AR200521A1 (ro)
AT (1) AT333954B (ro)
AU (1) AU461511B2 (ro)
BG (1) BG25070A3 (ro)
CA (1) CA1011736A (ro)
CH (1) CH589044A5 (ro)
CS (2) CS235092B2 (ro)
DD (1) DD114404A5 (ro)
DE (1) DE2418499C2 (ro)
DK (1) DK155662C (ro)
EG (1) EG11172A (ro)
ES (1) ES425221A1 (ro)
FI (1) FI60196C (ro)
FR (1) FR2226389B1 (ro)
GB (1) GB1458744A (ro)
HK (1) HK28279A (ro)
IE (1) IE40048B1 (ro)
IL (1) IL44492A (ro)
IN (1) IN138740B (ro)
KE (1) KE2937A (ro)
LU (1) LU69856A1 (ro)
MY (1) MY7900242A (ro)
NL (1) NL157893B (ro)
NO (1) NO146596C (ro)
PH (1) PH10555A (ro)
RO (2) RO80170A (ro)
SE (1) SE416645B (ro)
YU (1) YU39303B (ro)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550096A (en) * 1982-01-19 1985-10-29 Plurichemie Anstalt Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same
US4743699A (en) * 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
USRE32535E (en) * 1982-01-19 1987-10-27 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6343554U (ro) * 1986-09-05 1988-03-23
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
EP0391005B1 (en) * 1989-04-03 1991-10-16 Ranbaxy Laboratories, Ltd. Process for the production of alpha-6-deoxytetracyclines
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
JP2665395B2 (ja) * 1989-01-04 1997-10-22 フーバ，インコーポレーテッド α―６―デオキシテトラサイクリン類の製造法
DE102007003434A1 (de) 2007-01-23 2008-07-24 Jäger, Anton Reinigungsvorrichtung
CN105152961B (zh) * 2015-08-31 2017-07-11 河南师范大学 一种强力霉素中间体6‑次甲基土霉素的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (ro) * 1960-05-23 1966-05-25
GB1418137A (en) * 1972-02-24 1975-12-17 Ankerfarm Spa Process for the preparation of alpha-6-deoxytetracyclines

Also Published As

Publication number Publication date
CS235053B2 (en) 1985-04-16
FI60196C (fi) 1981-12-10
IE40048B1 (en) 1979-02-28
AT333954B (de) 1976-12-27
CA1011736A (en) 1977-06-07
NO146596B (no) 1982-07-26
KE2937A (en) 1979-03-30
AU461511B2 (en) 1975-05-29
GB1458744A (en) 1976-12-15
NO146596C (no) 1982-11-03
YU39303B (en) 1984-10-31
DK155662C (da) 1989-10-09
SE416645B (sv) 1981-01-26
ES425221A1 (es) 1976-05-16
EG11172A (en) 1977-01-31
NL7404666A (ro) 1974-10-22
LU69856A1 (ro) 1974-11-21
HK28279A (en) 1979-05-11
ATA292274A (de) 1976-04-15
FR2226389B1 (ro) 1976-12-17
IL44492A0 (en) 1974-06-30
JPS49135961A (ro) 1974-12-27
JPS5710863B2 (ro) 1982-03-01
AR200521A1 (es) 1974-11-15
DE2418499A1 (de) 1974-11-07
DD114404A5 (ro) 1975-08-05
MY7900242A (en) 1979-12-31
NL157893B (nl) 1978-09-15
BG25070A3 (en) 1978-07-12
DK155662B (da) 1989-05-01
AU6714374A (en) 1975-05-29
CH589044A5 (ro) 1977-06-30
IL44492A (en) 1977-01-31
PH10555A (en) 1977-06-08
FR2226389A1 (ro) 1974-11-15
RO80170A (ro) 1982-10-26
CS235092B2 (en) 1985-04-16
IN138740B (ro) 1976-03-27
DE2418499C2 (de) 1982-12-23
US3954862A (en) 1976-05-04
NO741223L (no) 1974-10-22
IE40048L (en) 1975-06-03
YU85974A (en) 1982-05-31
FI60196B (fi) 1981-08-31

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