SE398499B - Forfarande for framstellning av 2,4,5,6-tetrahydrocyklopenta/c/purrol-4-karboxamider och -4-tiokarboxamider med terapeutisk verkan - Google Patents

Forfarande for framstellning av 2,4,5,6-tetrahydrocyklopenta/c/purrol-4-karboxamider och -4-tiokarboxamider med terapeutisk verkan

Info

Publication number
SE398499B
SE398499B SE7404220A SE7404220A SE398499B SE 398499 B SE398499 B SE 398499B SE 7404220 A SE7404220 A SE 7404220A SE 7404220 A SE7404220 A SE 7404220A SE 398499 B SE398499 B SE 398499B
Authority
SE
Sweden
Prior art keywords
thiocarboxamids
purrol
tetrahydrocyclopenta
carboxamides
procedure
Prior art date
Application number
SE7404220A
Other languages
English (en)
Inventor
M R Bell
R Oesterlin
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Priority claimed from GB8385/76A external-priority patent/GB1496866A/en
Priority claimed from US05/703,949 external-priority patent/US4098797A/en
Publication of SE398499B publication Critical patent/SE398499B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7404220A 1973-03-29 1974-03-28 Forfarande for framstellning av 2,4,5,6-tetrahydrocyklopenta/c/purrol-4-karboxamider och -4-tiokarboxamider med terapeutisk verkan SE398499B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US346005A US3928380A (en) 1973-03-29 1973-03-29 1,1{40 -Spirobis(cyclopenta-{8 4,5-c{9 pyrroles)
GB8385/76A GB1496866A (en) 1975-03-17 1976-03-02 4,6,6-trimethyl-2,4,5,6-tetrahydrocyclopenta(c)pyrrole-4-carboxamides
US05/703,949 US4098797A (en) 1973-03-29 1976-07-09 Cyclopenta[c]pyrrole derivatives
US06/063,108 US4220763A (en) 1973-03-29 1979-08-02 Cyclopenta[o]pyrrole derivatives

Publications (1)

Publication Number Publication Date
SE398499B true SE398499B (sv) 1977-12-27

Family

ID=27447652

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7404220A SE398499B (sv) 1973-03-29 1974-03-28 Forfarande for framstellning av 2,4,5,6-tetrahydrocyklopenta/c/purrol-4-karboxamider och -4-tiokarboxamider med terapeutisk verkan

Country Status (10)

Country Link
US (4) US3928380A (sv)
JP (1) JPS49126663A (sv)
AT (1) AT330168B (sv)
BE (1) BE812999A (sv)
CA (1) CA1028707A (sv)
DE (1) DE2415404A1 (sv)
FR (1) FR2223038B1 (sv)
GB (2) GB1468042A (sv)
NL (1) NL7404193A (sv)
SE (1) SE398499B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239687A (en) * 1973-03-29 1980-12-16 Sterling Drug Inc. Cyclopenta[c]pyrrole derivatives
US3928380A (en) * 1973-03-29 1975-12-23 Sterling Drug Inc 1,1{40 -Spirobis(cyclopenta-{8 4,5-c{9 pyrroles)
US4339457A (en) * 1980-10-20 1982-07-13 Fmc Corporation 3-(Pyrrol-1-yl)phenylmethyl esters and intermediates
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
DE3722806A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag 7-(1h-pyrrol-3-yl)-substituierte 3,5-dihydroxy-hept-6-ensaeuren, 7-(1h-pyrrol-3-yl)-substituierte 3,5-dihydroxy-heptansaeuren, ihre entsprechenden (delta)-lactone und salze, verfahren zu ihrer herstellung ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US20050152323A1 (en) * 2004-01-12 2005-07-14 Vincent Bonnassieux Plug-in Wi-Fi access point device and system
IE20060197A1 (en) * 2005-03-14 2006-10-18 Pfizer Science & Tech Ltd Preparation of an atorvastatin intermediate
US7662831B2 (en) * 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) * 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3567361A (en) * 1969-08-29 1971-03-02 Us Agriculture Bis-pyrrolidone-formaldehyde addition products and their use as crosslinking agents with cellulose
GB1271122A (en) * 1969-10-03 1972-04-19 Science Union & Cie New azabicycloalkylurea derivatives and process for preparing them
US4008250A (en) * 1973-03-29 1977-02-15 Sterling Drug Inc. Cyclopenta[c]pyrrole derivatives
US3928380A (en) * 1973-03-29 1975-12-23 Sterling Drug Inc 1,1{40 -Spirobis(cyclopenta-{8 4,5-c{9 pyrroles)
GB1458217A (en) * 1973-12-14 1976-12-08 Science Union Et Ci Distributed azabicycloalkanes a process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB1468042A (en) 1977-03-23
FR2223038A1 (sv) 1974-10-25
FR2223038B1 (sv) 1977-12-09
US4140854A (en) 1979-02-20
DE2415404A1 (de) 1974-10-10
NL7404193A (sv) 1974-10-01
AT330168B (de) 1976-06-25
US4220763A (en) 1980-09-02
ATA262174A (de) 1975-09-15
CA1028707A (en) 1978-03-28
AU6704974A (en) 1975-09-25
BE812999A (fr) 1974-09-30
GB1468041A (en) 1977-03-23
JPS49126663A (sv) 1974-12-04
US3928380A (en) 1975-12-23
US4126620A (en) 1978-11-21

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