US3587897A - Container closure - Google Patents

Container closure Download PDF

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Publication number
US3587897A
US3587897A US836541A US3587897DA US3587897A US 3587897 A US3587897 A US 3587897A US 836541 A US836541 A US 836541A US 3587897D A US3587897D A US 3587897DA US 3587897 A US3587897 A US 3587897A
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Prior art keywords
cap
stopper
container
cover member
disc
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Expired - Lifetime
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US836541A
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Le Roy H Rohde
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West Pharmaceutical Services Inc
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West Co Inc
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/03Medical

Definitions

  • a container closure comprising a cap of cuplike form adapted to hold a stopper in place in a container, said cap having a top including inner and outer portions, means defining a partial score in said top defining an area of reduced cross section separating said inner and outer portions, means on said outer portion for securing the cap to the container to hold the stopper or disc in place and a cover member connected to said inner portion being actuatable' with respect to the outer portion to sever the top along the area of reduced cross section thereby to separate the inner portion from the outer portion.
  • This invention relates to an improvement in closures for pharmaceutical containers or bottles generally of the type shown in prior issued patents of the assignee of the present case, particularly Pat. No. 3,071,274 entitled Cap Structure for Bottles" issued Jan. 1, I963.
  • the cap member has a top which terminates in an inner edge defining an opening and the cover member has a depending portion which engages under the edge whereby upon actuation of the cover member the depending portion is severed to expose the stopper through the inner circular edge of the top.
  • the present invention is an improvement over these closures in that it provides a more effective seal excluding any dirt and foreign matter from entering into the area of the stopper and thus into the container and is also more economical to manufacture and assemble.
  • the closure of the present invention includes a cap member having a top and a depending skirt which is adapted to be crimped inwardly at its lower edge over the outer bead finish on the container to hold the stopper or disc in place.
  • the top of the cap has a partial score line defining in the illustrated embodiment a circular indentation in the top of a reduced thickness to define a disclike portion to which the cover member is secured.
  • the partial scoring is formed on the inner wall of the top confronting the stopper and the cover member has 21 depending portion having a locking flange by which it is secured to the disclike portion ofthe top defined by the partial scoring.
  • the cap member which may be formed by stamping circular discs from a large sheet of aluminum are simply formed with an interior partial scoring to define the central disc in one operation. Thereafter, the skirt is formed by a conventional forming operation and the cover member applied in the normal manner. The completed cap is then ready to assemble over a stopper to a container such as a pharmaceutical bottle.
  • FIG. 1 is a side elevation of a container closure in accordance with the present invention secured in position on a bottle;
  • FIG. 2 is an enlarged plan view of the cap with a portion of the cover broken away to more clearly illustrate the construction
  • FIG. 3 is an enlarged sectional view taken on lines 3-3 of FIG. 2;
  • FIG. 4 is a sectional view similar to FIG. 3 showing the cover member and disc in a detached position
  • FIG. 5 is an enlarged fragmentary perspective view of the central disc and a portion of the cover member removed from the remainder of the cap.
  • FIG. 1 there is shown a container or bottle of conventional form designated by the numeral 10, and a closure 12 in accordance with the present invention secured over the open end of the bottle.
  • the closure 12 holds a stopper [4 in the opening of the bottle.
  • the stopper 14 which may be formed of rubber or like material, has a hollow plug; portion 16 adapted to fit within the neck 18 of the bottle, a peripheral flange 20 which seats against the lip 22 of the bottle and a central thin wall portion 24 which may be pierced for example by the needle of a hypodermic syringe to gain access to the contents of the bottle.
  • the stopper illustrated is of conventional form and the present invention is not concerned with the specific configuration thereof.
  • a disclike liner may be employed which engages over the opening in the container and is held in place by the closure 12.
  • the closure for holding the stopper in place comprises a cap of generally cuplike form made out of sheet material such as aluminum, the cap 30 having a top 32 and a depending skirt 34 which is adapted to be crimped or spun at its lower terminal edge to provide an inwardly directed flange 36 which engages under a shoulder provided by the lip of the bottle thereby to secure the cap permanently to the bottle.
  • the top 32 of the cap member 30 is divided into an outer annular portion 40 and an inner central disc portion 42.
  • the disc portion 42 and outer annular portion 40 as illustrated are connected by fracturable bridge means in the present instance in the form of a partial score line 44 which is formed on the interior wall of the top confronting the stopper and provides a continuous circumferentially extending area 46 of reduced cross section or reduced thickness.
  • the outer annular portion 40 has a turned-in inner circumferentially extending terminal edge 48 adjacent the fracturable bridge means 44 and the disc 42 is slightly dished or outwardly flared.
  • the disc 42 is slightly frustoconical in shape.
  • the tamperproof closure assembly further includes an outer cover member 50 connected to the central disc portion 42 of the cap member adapted for actuation relative to the cap to remove the central disc portion and expose the stopper so that it may be pierced by a hypodermic syringe or the like.
  • the cover member 50 which may be made of a pliable material such as plastic is in generally disclike form and overlies the top portion and has an inner surface closely conforming to the configuration of the top portion of cap to snugly embrace the same in the assembled relation as shown in FIG. 3 and provide an effective seal.
  • the cover member as illustrated has a comparatively thin central portion 54 terminating at its outer peripheral edge in an enlarged flange portion 55 including a downwardly depending lip 56 which embraces the top and a portion of the skirt as illustrated and a raised rib 58. Further, the cover member has a depending central portion 60 engaging through an opening 62 in the disc 42 which terminates in an out-turned locking flange 64 thereby securing the cover member to the cap.
  • the closure assembly described above is relatively simple and economical to manufacture.
  • the cap which may be of thin-gauge aluminum may be stamped from a large sheet in a disclike form wherein the partial score line 44 is formed simultaneously with stamping of a disc member from the sheet material.
  • the central opening in the inner disc portion may be formed at that time.
  • conventional forming means may be employed to form the cap into the top configuration shown with the straight-sided skirt.
  • the locking flange Prior to assembly to the cap member the locking flange is a straight downwardly depending extension which may be directed outwardly by conventional means and application of heat and pressure.
  • the closure is now ready to be applied over a stopper and container by simply positioning it over the stopper and crimping the lower terminal edge of the skirt inwardly.
  • the user when the user desires to withdraw the contents from the container, the user simply supports the container in the palm of the hand with the tip of the thumb engaging the flange 55 of the cover 50. Upon exerting an upward force on the cover member, it is actuated upwardly relative to the cap with the point of the cover diametrically opposed from the point engaged by the thumb acting as a fulcrum. Thus, the center disc is fractured along the continuous circumferential score line 44. This exposes the central portion of the stopper so that it may be pierced by the hypodermic syringe. As noted previously, the configuration of the cover conforming closely to the top of the cap insures a tight sealing relation therebetw-een.
  • a container closure comprising a cap of cuplike form adapted to hold a stopper or liner in place in a container, said cap having a top including inner and outer portions, means defining a partial score in said top defining an area of reduced cross section separating said inner and outer portions, means on said outer portion for securing the cap to the container to hold the stopper in place and a cover member connected to said inner portion being actuatable with respect to the outer portion to sever the top along the area of reduced cross section thereby to separate the inner portion from the outer portion.
  • a container closure as claimed in claim 1 wherein said cover member is of generally disclike form and extends radially outwardly beyond the outer peripheral edge of said annular portion and has a depending flange whereby the cap is nested in said cover member to provide a seal.
  • a container closure as claimed in claim 1 including means defining an opening in said inner portion and wherein said cover member has locking means engaging through said opening to secure said cover member to said inner portion.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)

Abstract

A CONTAINER CLOSURE COMPRISING A CAP OF CUPLIKE FORM ADAPTED TO HOLD A STOPPER IN PLACE IN A CONTAINER, SAID CAP HAVING A TOP INCLUDING INNER AND OUTER PORTIONS, MEANS DEFINING A PARTIAL SCORE IN SAID TOP DEFINING AN AREA OF REDUCED CROSS SECTION SEPARATING SAID INNER AND OUTER PORTIONS, MEANS ON SAID OUTER PORTION FOR SECURING THE CAP TO THE CONTAINER TO HOLD THE STOPPER OR DISC IN PLACE AND A COVER MEMBER CONNECTED TO SAID INNER PORTION BEING ACTUATABLE WILL RESPECT TO THE OUTER PORTION TO SEVER THE TOP ALONG THE AREA OF REDUCED CROSS SECTION THEREBY TO SEPARATE THE INNER PORTION FROM THE OUTER PORTION.

Description

United States Patent [72] Inventor Le Roy H. Rohde Malvern, Pa. [21 Appl. No. 836,541 [22] Filed June 25, 1969 ,[45] Patented June 28, 1971 [73] Assignee The West Company Phoenixville, Pa.
[54] CONTAINER CLOSURE 6 Claims, 5 Drawing Figs.
[521 [1.8. CI 215/38, 215/46 [51] Int. Cl 865d 41/42 [50] Field 01 Search 215/37, 38, 46.5
[56] References Cited UNITED STATES PATENTS 3,071,274 1/1963 Ravn 215/37 3,358,865 12/1967 Andersen. 3,477,603 l1/l969 Koll Primary Examiner-Donald F. Norton Attorney- Howson and Howson ABSTRACT: A container closure comprising a cap of cuplike form adapted to hold a stopper in place in a container, said cap having a top including inner and outer portions, means defining a partial score in said top defining an area of reduced cross section separating said inner and outer portions, means on said outer portion for securing the cap to the container to hold the stopper or disc in place and a cover member connected to said inner portion being actuatable' with respect to the outer portion to sever the top along the area of reduced cross section thereby to separate the inner portion from the outer portion.
PATENTED JUN28I97I 3587897 F IGI. F163.
INVENTOR; LEROY H. ROHDE ATTYS.
CONTAINER CLOSURE This invention relates to an improvement in closures for pharmaceutical containers or bottles generally of the type shown in prior issued patents of the assignee of the present case, particularly Pat. No. 3,071,274 entitled Cap Structure for Bottles" issued Jan. 1, I963.
This prior closure which is used to hold a stopper in the opening of a bottle or the like comprises a cap member of sheet metal such as aluminum having an annular top with a control disc connected to the top by fracturable bridge members and a cover member secured to the central disc member which is actuatable relative to the cap to fracture the bridges and expose the stopper through the opening provided upon removal of the central disc.
In other cases, for example as shown in US. Pat. No. 3,l93,l28 entitled Container Closure" issued July 6, 1965, the cap member has a top which terminates in an inner edge defining an opening and the cover member has a depending portion which engages under the edge whereby upon actuation of the cover member the depending portion is severed to expose the stopper through the inner circular edge of the top.
While these prior constructions are generally suitable for the purposes indicated, the present invention is an improvement over these closures in that it provides a more effective seal excluding any dirt and foreign matter from entering into the area of the stopper and thus into the container and is also more economical to manufacture and assemble.
More specifically, the closure of the present invention includes a cap member having a top and a depending skirt which is adapted to be crimped inwardly at its lower edge over the outer bead finish on the container to hold the stopper or disc in place. In the present instance the top of the cap has a partial score line defining in the illustrated embodiment a circular indentation in the top of a reduced thickness to define a disclike portion to which the cover member is secured. In the preferred form the partial scoring is formed on the inner wall of the top confronting the stopper and the cover member has 21 depending portion having a locking flange by which it is secured to the disclike portion ofthe top defined by the partial scoring.
By this construction it has been found that there is an effective seal in the assembled relation which precludes any dirt or foreign matter from entering into the area of the stopper. Additionally, since the depth of the scoring can be controlled very accurately, the amount of force required to fracture the scoring upon actuation of the cover member is uniform regardless of where the cover member is engaged about its periphery. This is not the case in connection with the previous closures where the disc member was connected to the annular portion of the top by, for example, three circumferentially spaced bridge members. It is also true of the embodiment where the depending portion of the cover member had three circumferentially spaced areas of increased cross section to effectively provide areas ofincreased resistance to removing the cover member or bridge members. Moreover, the present assembly is very easy and economical to manufacture. For example, the cap member which may be formed by stamping circular discs from a large sheet of aluminum are simply formed with an interior partial scoring to define the central disc in one operation. Thereafter, the skirt is formed by a conventional forming operation and the cover member applied in the normal manner. The completed cap is then ready to assemble over a stopper to a container such as a pharmaceutical bottle.
The foregoing and other objects of the invention and the various details of the construction thereof are hereinafter more fully described and set forth with reference to the ac: companying drawing, in which:
FIG. 1 is a side elevation of a container closure in accordance with the present invention secured in position on a bottle;
FIG. 2 is an enlarged plan view of the cap with a portion of the cover broken away to more clearly illustrate the construction;
FIG. 3 is an enlarged sectional view taken on lines 3-3 of FIG. 2;
FIG. 4 is a sectional view similar to FIG. 3 showing the cover member and disc in a detached position; and
FIG. 5 is an enlarged fragmentary perspective view of the central disc and a portion of the cover member removed from the remainder of the cap.
Referring now to the drawing and particularly FIG. 1 thereof, there is shown a container or bottle of conventional form designated by the numeral 10, and a closure 12 in accordance with the present invention secured over the open end of the bottle. As seen in FIG. 3, the closure 12 holds a stopper [4 in the opening of the bottle. The stopper 14 which may be formed of rubber or like material, has a hollow plug; portion 16 adapted to fit within the neck 18 of the bottle, a peripheral flange 20 which seats against the lip 22 of the bottle and a central thin wall portion 24 which may be pierced for example by the needle of a hypodermic syringe to gain access to the contents of the bottle. The stopper illustrated is of conventional form and the present invention is not concerned with the specific configuration thereof. For example, in lieu of the stopper 14, a disclike liner may be employed which engages over the opening in the container and is held in place by the closure 12.
The closure for holding the stopper in place comprises a cap of generally cuplike form made out of sheet material such as aluminum, the cap 30 having a top 32 and a depending skirt 34 which is adapted to be crimped or spun at its lower terminal edge to provide an inwardly directed flange 36 which engages under a shoulder provided by the lip of the bottle thereby to secure the cap permanently to the bottle.
In the present instance the top 32 of the cap member 30 is divided into an outer annular portion 40 and an inner central disc portion 42. The disc portion 42 and outer annular portion 40 as illustrated are connected by fracturable bridge means in the present instance in the form of a partial score line 44 which is formed on the interior wall of the top confronting the stopper and provides a continuous circumferentially extending area 46 of reduced cross section or reduced thickness. As best illustrated in FIGS. 3 and 4, the outer annular portion 40 has a turned-in inner circumferentially extending terminal edge 48 adjacent the fracturable bridge means 44 and the disc 42 is slightly dished or outwardly flared. In other words, in the preferred form the disc 42 is slightly frustoconical in shape.
The tamperproof closure assembly further includes an outer cover member 50 connected to the central disc portion 42 of the cap member adapted for actuation relative to the cap to remove the central disc portion and expose the stopper so that it may be pierced by a hypodermic syringe or the like. The cover member 50 which may be made of a pliable material such as plastic is in generally disclike form and overlies the top portion and has an inner surface closely conforming to the configuration of the top portion of cap to snugly embrace the same in the assembled relation as shown in FIG. 3 and provide an effective seal. The cover member as illustrated has a comparatively thin central portion 54 terminating at its outer peripheral edge in an enlarged flange portion 55 including a downwardly depending lip 56 which embraces the top and a portion of the skirt as illustrated and a raised rib 58. Further, the cover member has a depending central portion 60 engaging through an opening 62 in the disc 42 which terminates in an out-turned locking flange 64 thereby securing the cover member to the cap.
The closure assembly described above is relatively simple and economical to manufacture. For example, the cap which may be of thin-gauge aluminum may be stamped from a large sheet in a disclike form wherein the partial score line 44 is formed simultaneously with stamping of a disc member from the sheet material. Also the central opening in the inner disc portion may be formed at that time. Thereafter conventional forming means may be employed to form the cap into the top configuration shown with the straight-sided skirt. Prior to assembly to the cap member the locking flange is a straight downwardly depending extension which may be directed outwardly by conventional means and application of heat and pressure. The closure is now ready to be applied over a stopper and container by simply positioning it over the stopper and crimping the lower terminal edge of the skirt inwardly.
Now with reference to FIG. 4, when the user desires to withdraw the contents from the container, the user simply supports the container in the palm of the hand with the tip of the thumb engaging the flange 55 of the cover 50. Upon exerting an upward force on the cover member, it is actuated upwardly relative to the cap with the point of the cover diametrically opposed from the point engaged by the thumb acting as a fulcrum. Thus, the center disc is fractured along the continuous circumferential score line 44. This exposes the central portion of the stopper so that it may be pierced by the hypodermic syringe. As noted previously, the configuration of the cover conforming closely to the top of the cap insures a tight sealing relation therebetw-een. Additionally, since there is no perforation in the top of the cap as was the case with prior closures of this type discussed above, there is a complete seal between the outer cap member and stopper to preclude infiltration of dirt and foreign matter. Additionally, by reason of the partial score line configuration providing a cross section of reduced thickness of substantially the same cross section around the entire periphery of the juncture between the disc and outer top, the force required to remove the disc is uniform regardless of where it is engaged by the user. This was not the case in prior arrangements where the central disc was connected to the annular portion of the top by circumferentially spaced bridge connections. The turned-in circumferentially extending edge portion 48 strengthens the outer annular portion 40 of the cap and serves to prevent deformation of the cap upon removal of the central disc portion 42. Moreover, by
this construction the inner edge of the outer annular portion imbeds itself into the resilient material of the stopper so that there is less chance of catching cotton on the torn edge when cleaning the exposed center section of the rubber stopper.
lclaim:
, l. A container closure comprising a cap of cuplike form adapted to hold a stopper or liner in place in a container, said cap having a top including inner and outer portions, means defining a partial score in said top defining an area of reduced cross section separating said inner and outer portions, means on said outer portion for securing the cap to the container to hold the stopper in place and a cover member connected to said inner portion being actuatable with respect to the outer portion to sever the top along the area of reduced cross section thereby to separate the inner portion from the outer portion.
2. A container closure as claimed in claim 1 wherein said cover member is of generally disclike form and extends radially outwardly beyond the outer peripheral edge of said annular portion and has a depending flange whereby the cap is nested in said cover member to provide a seal.
3. A container closure as claimed in claim 1 wherein said partial score is continuous and of circular configuration to define a disclike inner top portion.
4. A container closure as claimed in claim 1 including means defining an opening in said inner portion and wherein said cover member has locking means engaging through said opening to secure said cover member to said inner portion.
5. A container closure as claimed in claim 4 wherein said locking means comprises an out turned flange.
6. A container closure as claimed in claim I wherein said partial score is on the inner face of said top.
US836541A 1969-06-25 1969-06-25 Container closure Expired - Lifetime US3587897A (en)

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Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3712498A (en) * 1971-10-27 1973-01-23 Aluminum Co Of America Container closure
US3963141A (en) * 1975-05-21 1976-06-15 Liu Ming Jen Closure cap with self-opening means
FR2390341A1 (en) * 1977-05-09 1978-12-08 Asicomo As RECEPTACLE CLOSURE AND PROCEDURE TO ACHIEVE IT
EP0006032A1 (en) * 1978-06-05 1979-12-12 Merck & Co. Inc. Tamperproof container
US4187149A (en) * 1978-02-27 1980-02-05 Monsanto Company Cell culture sampling system
US4227617A (en) * 1979-08-30 1980-10-14 Aluminum Company Of America Container closure
US4265364A (en) * 1978-08-25 1981-05-05 Zenyu Kinzoku Co., Ltd. Bottle cap
US4562932A (en) * 1983-10-06 1986-01-07 Franz Pohl Metall- Und Kunststoffwarenfabrik Gmbh Cap closure for a container with pharmaceutical contents
US4664277A (en) * 1983-03-14 1987-05-12 The West Company Bonded closure assembly
WO1988006556A1 (en) * 1987-03-06 1988-09-07 Pharma-Metall Gmbh Closure for a receptacle, particularly for pharmaceutical receptacles
EP0291658A1 (en) * 1987-05-07 1988-11-23 Pohl GmbH & Co. KG Closure cap for infusion and transfusion bottles
EP0330883A1 (en) * 1988-03-03 1989-09-06 Pohl GmbH & Co. KG Stopper for infusion and transfusion bottles
US5038952A (en) * 1989-12-14 1991-08-13 Coors Brewing Company Closure assembly for pressurized plastic beverage container
US5080245A (en) * 1990-03-22 1992-01-14 The West Company Incorporated Bidirectional scoring
US5152413A (en) * 1990-07-26 1992-10-06 The West Company, Incorporated Bridge design for tamper evident closures
US5335801A (en) * 1992-08-13 1994-08-09 Lee Yong Hak Stopper sealing cap for injectable fluid bottle
US5555988A (en) * 1994-05-04 1996-09-17 Hoechst Aktiengesellschaft Closure with tamper-indicating cap for injecton and infusion bottles
US5890610A (en) * 1996-09-17 1999-04-06 Jansen; Hubert Vial connector assembly for a medicament container
US6241112B1 (en) * 1997-12-09 2001-06-05 Helvoet Pharma Belgium N.V. Stopper for sealing infusion bottles
US20160194121A1 (en) * 2013-09-02 2016-07-07 Taisei Kako Co., Ltd. Cap for vial
US20170334585A1 (en) * 2000-02-11 2017-11-23 Medinstill Development Llc Sealed containers and methods of filling and resealing same
US20220241149A1 (en) * 2019-07-02 2022-08-04 Taisei Kako Co., Ltd. Cap and capped vial

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3712498A (en) * 1971-10-27 1973-01-23 Aluminum Co Of America Container closure
US3963141A (en) * 1975-05-21 1976-06-15 Liu Ming Jen Closure cap with self-opening means
FR2390341A1 (en) * 1977-05-09 1978-12-08 Asicomo As RECEPTACLE CLOSURE AND PROCEDURE TO ACHIEVE IT
US4205754A (en) * 1977-05-09 1980-06-03 Oniba I/S Container closure and a method of making the same
US4187149A (en) * 1978-02-27 1980-02-05 Monsanto Company Cell culture sampling system
EP0006032A1 (en) * 1978-06-05 1979-12-12 Merck & Co. Inc. Tamperproof container
US4265364A (en) * 1978-08-25 1981-05-05 Zenyu Kinzoku Co., Ltd. Bottle cap
US4227617A (en) * 1979-08-30 1980-10-14 Aluminum Company Of America Container closure
DE3028281A1 (en) * 1979-08-30 1982-02-18 Aluminum Company Of America, Pittsburgh, Pa. LOCKING ARRANGEMENT
US4664277A (en) * 1983-03-14 1987-05-12 The West Company Bonded closure assembly
US4562932A (en) * 1983-10-06 1986-01-07 Franz Pohl Metall- Und Kunststoffwarenfabrik Gmbh Cap closure for a container with pharmaceutical contents
WO1988006556A1 (en) * 1987-03-06 1988-09-07 Pharma-Metall Gmbh Closure for a receptacle, particularly for pharmaceutical receptacles
EP0291658A1 (en) * 1987-05-07 1988-11-23 Pohl GmbH & Co. KG Closure cap for infusion and transfusion bottles
EP0330883A1 (en) * 1988-03-03 1989-09-06 Pohl GmbH & Co. KG Stopper for infusion and transfusion bottles
US5038952A (en) * 1989-12-14 1991-08-13 Coors Brewing Company Closure assembly for pressurized plastic beverage container
US5080245A (en) * 1990-03-22 1992-01-14 The West Company Incorporated Bidirectional scoring
US5152413A (en) * 1990-07-26 1992-10-06 The West Company, Incorporated Bridge design for tamper evident closures
US5335801A (en) * 1992-08-13 1994-08-09 Lee Yong Hak Stopper sealing cap for injectable fluid bottle
US5555988A (en) * 1994-05-04 1996-09-17 Hoechst Aktiengesellschaft Closure with tamper-indicating cap for injecton and infusion bottles
US5890610A (en) * 1996-09-17 1999-04-06 Jansen; Hubert Vial connector assembly for a medicament container
US6241112B1 (en) * 1997-12-09 2001-06-05 Helvoet Pharma Belgium N.V. Stopper for sealing infusion bottles
US20170334585A1 (en) * 2000-02-11 2017-11-23 Medinstill Development Llc Sealed containers and methods of filling and resealing same
US20160194121A1 (en) * 2013-09-02 2016-07-07 Taisei Kako Co., Ltd. Cap for vial
US9555940B2 (en) * 2013-09-02 2017-01-31 Taisei Kako Co., Ltd. Cap for vial
US9555941B2 (en) * 2013-09-02 2017-01-31 Taisei Kako Co., Ltd. Cap for vial
US20160200489A1 (en) * 2013-09-02 2016-07-14 Taisei Kako Co.,Ltd. Cap for vial
US20220241149A1 (en) * 2019-07-02 2022-08-04 Taisei Kako Co., Ltd. Cap and capped vial
US12115127B2 (en) * 2019-07-02 2024-10-15 Taisei Kako Co., Ltd. Cap and capped vial

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