gout

Kennedy loves to talk about "chronic disease," but doesn't mention how once-common disabling conditions like gout, rickets, polio injury, or consumption have disappeared.

Mr Rooney also has epilepsy, colitis and gout, and had recently been in and out of hospital.

This discovery could be helpful for the treatment of diseases in which inflammatory processes play a role -- such as gout, type 2 diabetes or severe cases of COVID-19.

However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer's, Parkinson's, multiple sclerosis, atherosclerosis, gout, and type II diabetes.

Investors will be keen to see whether Amgen, which has operations around the world, can help boost sales of Horizon's two key products, thyroid eye disease treatment Tepezza and gout drug Krystexxa.