KEGG ENZYME: 6.3.2.51

ENZYME: 6.3.2.51

Entry

EC 6.3.2.51                 Enzyme

Name

phosphopantothenate---cysteine ligase (ATP);
phosphopantothenoylcysteine synthetase (ambiguous);
PPCS (gene name)

Class

Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)

Sysname

(R)-4'-phosphopantothenate:L-cysteine ligase (ATP-utilizing)

Reaction(IUBMB)

ATP + (R)-4'-phosphopantothenate + L-cysteine = AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine [RN:R04230]

Reaction(KEGG)

R04230

Substrate

ATP [CPD:C00002];
(R)-4'-phosphopantothenate [CPD:C03492];
L-cysteine [CPD:C00097]

Product

AMP [CPD:C00020];
diphosphate [CPD:C00013];
N-[(R)-4'-phosphopantothenoyl]-L-cysteine [CPD:C04352]

Comment

A key enzyme in the production of coenzyme A. The eukaryotic enzyme requires ATP, in contrast to the bacterial enzyme, EC 6.3.2.5, phosphopantothenate---cysteine ligase (CTP), which requires CTP.

History

EC 6.3.2.51 created 2017

Pathway

ec00770

Pantothenate and CoA biosynthesis

Orthology

K01922

phosphopantothenate---cysteine ligase (ATP)

Genes

HSA:	79717(PPCS)

PTR:	747056(PPCS)

PPS:	100969367(PPCS)

GGO:	101138135(PPCS)

PON:	134759346(PPCS)

PPYG:

129038871(PPCS)

NLE:	100591238(PPCS)

HMH:	116463703 116463731

SSYN:

129469252(PPCS)

MCC:	697064(PPCS)

MCF:	102127325(PPCS)

MTHB:

126960538

MNI:	105494845(PPCS)

CATY:

105594665(PPCS)

PANU:

101019902(PPCS)

TGE:	112622795(PPCS)

MLEU:

105555030(PPCS)

RRO:	104668997(PPCS)

RBB:	108530371(PPCS)

TFN:	117092763(PPCS)

PTEH:

111548701(PPCS)

CANG:

105513899(PPCS)

CJC:	100414413(PPCS)

SBQ:	101027483(PPCS)

CIMI:

108313384(PPCS)

CSYR:

103269616(PPCS)

MMUR:

105862279(PPCS) 105866347

LCAT:

123634281(PPCS)

PCOQ:

105812352(PPCS)

OGA:	100962200(PPCS)

MMU:	106564(Ppcs)

MCAL:

110293510(Ppcs)

MPAH:

110323533(Ppcs)

RNO:	298490(Ppcs)

MCOC:

116096540(Ppcs)

ANU:	117709274(Ppcs)

ASYL:

127681195(Ppcs)

MUN:	110547469(Ppcs)

CGE:	100768962(Ppcs)

MAUA:

101825463(Ppcs)

PROB:

127225079(Ppcs)

PLEU:

114704935(Ppcs)

MORG:

121447904(Ppcs)

MFOT:

126513154

AAMP:

119816771(Ppcs)

NGI:	103741896(Ppcs)

HGL:	101722213(Ppcs)

CPOC:

100713605(Ppcs)

CCAN:

109691199(Ppcs)

DORD:

105986203(Ppcs)

DSP:	122108961(Ppcs)

PLOP:

125355002(Ppcs)

NCAR:

124990562

MMMA:

107140417 107141886(Ppcs)

ITI:	101973297(Ppcs)

OCU:

100357911

OPI:	101535629(PPCS)

TUP:	102492271(PPCS)

GVR:	103602405(PPCS)

CFA:	475309(PPCS)

CLUD:

112642265(PPCS)

VVP:	112908230(PPCS)

VLG:	121481620(PPCS)

NPO:	129520493(PPCS)

AML:	100472297(PPCS)

UAH:	113254811(PPCS)

UAR:	123793825(PPCS)

ELK:

111143172

LLV:

125098361

MPUF:

101685440(PPCS)

MNP:	132000688(PPCS)

MLK:	131809447(PPCS)

NVS:	122899836(PPCS)

ORO:	101367565(PPCS)

EJU:	114224214(PPCS)

ZCA:	113910250(PPCS)

MLX:	118019546(PPCS)

NSU:	110574948(PPCS)

LWW:	102734203(PPCS)

FCA:	101093376(PPCS)

PYU:	121026954(PPCS)

PCOO:

112871728(PPCS)

PBG:	122480353(PPCS)

PVIV:

125173107(PPCS)

LRUF:

124515959

LGF:	123597704(PPCS)

AJU:

106970199

PTG:	102952696(PPCS)

PPAD:

109254895(PPCS)

PUC:

125912711

PLEZ:

122226768(PPCS)

HHV:	120236102(PPCS)

BTA:	539294(PPCS)

BOM:	102286433(PPCS)

BIU:	109556430(PPCS)

BBUB:

102407720(PPCS)

BBIS:

105004894(PPCS)

OAS:	100145879(PPCS)

BTAX:

128044735(PPCS)

CSUM:

138073354(PPCS)

ODA:	120856318(PPCS)

CCAD:

122437134(PPCS) 122446657

MREE:

136153316(PPCS)

OVR:	110151390(PPCS)

MBEZ:

129541503(PPCS)

SSC:	100523850(PPCS)

CBAI:

105072741(PPCS)

CDK:	105101636(PPCS)

VPC:	102544832(PPCS)

BACU:

103017104(PPCS)

BMUS:

118884732(PPCS)

LVE:	103082840(PPCS)

OOR:	101275156(PPCS)

LALB:

132514880

DLE:	111175676(PPCS)

PCAD:

102982388(PPCS)

PSIU:

116742038(PPCS)

NASI:

112399552(PPCS)

ECB:	100067429(PPCS)

EPZ:	103557318(PPCS)

EAI:	106847804(PPCS)

MYB:	102263608(PPCS)

MYD:

102754989

MMYO:

118675940(PPCS)

MLF:	102429882(PPCS)

MDT:	132231151(PPCS)

MYUM:

139003306(PPCS)

PKL:	118722913(PPCS)

EFUS:

103294843(PPCS)

MNA:	107531163(PPCS)

DRO:	112299406(PPCS)

SHON:

118977579(PPCS)

AJM:	119052414(PPCS)

PDIC:

114496621(PPCS)

PHAS:

123832023(PPCS)

MMF:	118626463(PPCS)

PPAM:

129069359(PPCS)

HAI:	109383329(PPCS)

PALE:

102883263(PPCS)

PGIG:

120607196(PPCS)

PVP:	105304027(PPCS)

RAY:	107508300(PPCS)

MJV:	108399394(PPCS) 118969310

TOD:	119237174(PPCS)

SARA:

101546571(PPCS)

SFUM:

130031732(PPCS)

SETR:

126011220(PPCS) 126028154

LAV:	100675395(PPCS)

TMU:

101359260

ETF:	101661629(PPCS)

DNM:	101420657(PPCS)

GAS:	123243216(PPCS)

AFZ:

127555546

PCW:	110206225(PPCS)

TVP:	118837655(PPCS)

OAA:

100074041

GGA:	100859789(PPCS)

PCOC:

116238364(PPCS)

MGP:	100548772(PPCS)

CJO:	107323493(PPCS)

TPAI:

128084859(PPCS)

LMUT:

125703498(PPCS)

NMEL:

110408744(PPCS)

APLA:

101794666(PPCS)

ACYG:

106049734(PPCS)

CATA:

118258820(PPCS)

TGU:	100190089(PPCS)

LSR:	110474448(PPCS)

SCAN:

103820860(PPCS)

PMOA:

120496749(PPCS)

OTC:	121343922(PPCS)

PRUF:

121351424(PPCS)

ATRC:

139600642(PPCS)

FAB:	101809422(PPCS)

OMA:	130261601(PPCS)

PHI:	102105519(PPCS)

PMAJ:

107213781(PPCS)

CCW:	104698568(PPCS)

ACOE:

138121286(PPCS)

ETL:	114070822(PPCS)

ZLE:	135456718(PPCS)

SVG:	106860555(PPCS)

MMEA:

130585905(PPCS)

HRT:	120762197(PPCS)

SATI:

136370861(PPCS)

CCIC:

134052858(PPCS)

SHAB:

115617514(PPCS)

TALA:

104364123(PPCS)

ACHC:

115342427(PPCS)

HHAR:

128143917(PPCS)

GCL:

127024936

CUCA:

104062255(PPCS)

RTD:	128918464(PPCS)

NPD:	112959614(PPCS)

ASN:	102384769(PPCS)

AMJ:	102563930(PPCS)

CPOO:

109314290(PPCS)

GGN:	109293871(PPCS)

PSS:	102461376(PPCS)

CMY:	102947115(PPCS)

CCAY:

125624332(PPCS)

DCC:	119845030(PPCS)

CPIC:

101937310(PPCS)

TST:	117867946(PPCS)

MRV:	120387953(PPCS)

ASAO:

132764668(PPCS)

PMUR:

107291366(PPCS)

CTIG:

120319089(PPCS)

PGUT:

117669661(PPCS)

APRI:

131187008(PPCS)

PTEX:

113449755(PPCS)

NSS:	113423961(PPCS)

PMUA:

114602330(PPCS)

PRAF:

128419553(PPCS)

ZVI:	118085890(PPCS)

HCG:	128338365(PPCS)

GJA:	107121306(PPCS)

STOW:

125445623(PPCS)

XLA:	444166(ppcs.L)

XTR:	780088(ppcs)

NPR:	108783951(PPCS)

RTEM:

120915611(PPCS)

BBUF:

120998188(PPCS)

BGAR:

122928881(PPCS)

PWL:	138300905(PPCS)

MUO:	115482634(PPCS)

GSH:	117348999(PPCS)

DRE:	561272(ppcs)

SRX:

107749447

SANH:

107685733 107691385

SGH:	107551114 107565714

CCAR:

109090824 109098837(ppcs)

CAUA:

113095929 113111127

CGIB:

127968544 128022283

PTET:

122354479(ppcs)

LROH:

127172688(ppcs)

OMC:	131549850(ppcs)

PPRM:

120480647(ppcs)

RKG:	130085600(ppcs)

MAMB:

125256668(ppcs)

CIDE:

127522667

CERY:

137021063(ppcs)

MASI:

127426218 127427603

TROS:

130571178(ppcs)

TDW:	130410780(ppcs)

MANU:

129428053(ppcs)

PDAB:

135718878(ppcs)

IPU:	100528440(ppcs)

IFU:	128625193(ppcs)

PHYP:

113538003(ppcs)

SMEO:

124402487(ppcs)

TFD:	113641328(ppcs)

TVC:	132838026(ppcs)

CGAR:

128511620(ppcs)

NGRA:

132874377(ppcs)

TRN:	134301504(ppcs)

AMEX:

103033972(ppcs)

CMAO:

118799511(ppcs)

EEE:	113589351(ppcs)

CHAR:

105904177(ppcs)

SPIL:

134092372(ppcs)

TRU:	101077805(ppcs)

TFS:	130524002(ppcs)

TNG:	GSTEN00027553G001

LCO:	104919367(ppcs)

NCC:	104951534(ppcs)

TBEN:

117489702(ppcs)

CGOB:

115008749(ppcs)

PGEO:

117446847(ppcs)

GACU:

117548218(ppcs)

EMAC:

134883295(ppcs)

ELY:	117257560(ppcs)

EFO:	125893141(ppcs)

PLEP:

121959361(ppcs)

SLUC:

116051408(ppcs)

ECRA:

117943155(ppcs)

ESP:	116688201(ppcs)

PFLV:

114554799(ppcs)

GAT:	120835171(ppcs)

PPUG:

119193878(ppcs)

AFB:	129105698(ppcs)

CLUM:

117731179(ppcs)

PSWI:

130208905(ppcs)

CANA:

137796675(ppcs)

CVE:	137873829(ppcs)

MSAM:

119886795(ppcs)

SCHU:

122885936(ppcs)

CUD:	121528040(ppcs)

SPUL:

138605721(ppcs)

LMIX:

132978079(ppcs)

ALAT:

119021143(ppcs)

ASTR:

137595065(ppcs)

MZE:	101472115(ppcs)

ONL:	100697161(ppcs)

OAU:	116334212(ppcs)

OLA:	101171657(ppcs)

OML:	112144767(ppcs)

CSAI:

133448649(ppcs)

XMA:	102225955(ppcs)

XCO:	114135978(ppcs)

XHE:	116711076(ppcs)

PRET:

103464482(ppcs)

PFOR:

103136679(ppcs)

PLAI:

106945819(ppcs)

PMEI:

106924799(ppcs)

GAF:	122833637(ppcs)

PPRL:

129358438(ppcs)

CVG:	107087511(ppcs)

CTUL:

119772753(ppcs)

GMU:	124857178(ppcs)

NFU:	107385253(ppcs)

KMR:	108231112(ppcs)

ALIM:

106513855(ppcs)

NWH:	119412391(ppcs)

AOCE:

111588014(ppcs)

EJA:	138196033(ppcs)

BFRE:

138616494(ppcs)

MCEP:

125006783(ppcS)

CSEM:

103385673(ppcs)

POV:	109638627(ppcs)

SSEN:

122768415(ppcs)

SSOE:

131460969(ppcs)

HHIP:

117761739(ppcs)

HSP:	118105201(ppcs)

PPLT:

128449357(ppcs)

SMAU:

118309012(ppcs)

LCF:

108899884

SDU:	111224029(ppcs)

SLAL:

111658270(ppcs)

XGL:	120783214(ppcs)

HCQ:	109529187(ppcs)

SSCV:

125977702(ppcs)

SBIA:

133508034(ppcs)

PEE:	133408324(ppcs)

PTAO:

133484104(ppcs)

BPEC:

110168650(ppcs)

MALB:

109959069(ppcs)

BSPL:

114856135(ppcs)

SJO:	128355142(ppcs)

SSCO:

133977792(ppcs)

GMH:	115557072(ppcs)

SASA:

100195917(ppcs)

STRU:

115150922(ppcs)

OTW:	112254313(ppcs)

OMY:	110527825(ppcs)

OGO:	124020870(ppcs)

ONE:	115145423(ppcs)

OKI:	109890900(ppcs)

OKE:	118400032(ppcs)

OMM:	135540255 135542204(ppcs)

OCLA:

139414239

SALP:

111969807(ppcs)

SNH:	120065629(ppcs)

CCLU:

121578730(ppcs)

ELS:	105017418(ppcs)

SFM:	108918354(ppcs)

PKI:	111857030(ppcs)

AANG:

118211730(ppcs)

AROT:

135238239(ppcs)

CCOG:

133110624(ppcs)

LOC:	102690568(ppcs)

PSPA:

121329062 121329290

ARUT:

117425455(ppcs)

PSEX:

120530965(ppcs)

LCM:	102354936(PPCS)

CMK:	103190078(ppcs)

RTP:	109914734(ppcs)

CPLA:

122540249(ppcs)

HOC:	132833713(ppcs)

LERI:

129711476(ppcs)

BFO:

118432735

BBEL:

109475808

CIN:

100187386

SCLV:

120330713 120330890

SPU:	115930015 763180

LPIC:

129256453

AJJ:

139966087

APLC:

110986600

ARUN:

117287805

AAMU:

139937612

AFIL:

140150243

AJC:

117115170

PFLL:

139139797

DME:	Dmel_CG5629(Ppcs)

DER:

6553807

DSE:

6619106

DSI:	Dsimw501_GD20133(Dsim_GD20133)

DYA:	Dyak_GE25151

DAN:

6501707

DSR:

110188289

DPO:

4801007

DPE:

6588107

DMN:

108156647

DWI:

6650618

DGR:

6563511

DMO:	Dmoj_GI24057

DAZ:

108621442

DNV:

108656764

DHE:

111601755

DVI:	6629969(Ppcs)

CCAT:

101460214

BOD:

106622346

BDR:

105227635

RZE:	108362270 108368118

AOQ:

129235336

TDA:	119685583 119685584

MDE:

101896548

SCAC:

106086952

LCQ:

111677515

LSQ:

119614449

CVJ:	135951459(Ppcs)

GFS:

119640725

ECOE:

129953631

CLON:

129611767

HIS:

119653039

AGA:

1274457

ACOZ:

120948848

AARA:

120898799

AMER:

121603528

ASTE:

118504678 118517182

AMAP:

126558582

AFUN:

125774805

AMOU:

128297126

AALI:

118460159

AAG:

5566454

AALB:

109411495 109414891

ASUA:

134222661

CQU:	CpipJ_CPIJ005389

CPII:

120414284

CNS:

116338520

BCOO:

119067862

LLL:

129788010

PPAP:

129799887

AME:

411581

ACER:

108001779

ALAB:

122719780

ADR:

102681684

AFLR:

100863629

BIM:

100740383

BBIF:

117207594

BVK:

117232053

BVAN:

117156768

BHUN:

126867813

BTER:

100650397

BAFF:

126914070

BPYO:

122566620

BPAS:

132909965

FVI:

122528538

CCAL:

108628133

OBB:

114872026

OLG:

117601289

MGEN:

117221565

NMEA:

116432467

CGIG:

122397541

SOC:

105205708

MPHA:

105840145

AEC:

105147096

ACEP:

105623733

PBAR:

105431579

VEM:

105560163

COBS:

139107176 139107177

TLN:	139821105(Ppcs)

HST:

105192129

DQU:

106741223

CFO:

105248320

FEX:

115245119

PMEC:

138942270(Ppcs)

LHU:	105677782(Ppcs)

PGC:

109858729

OBO:

105285709

PCF:

106786200

PFUC:

122525447

VPS:

122633337

VCRB:

124429478

VVE:

124953655

NVI:

100118134

CSOL:

105364493 105364496 105367020

TPRE:

106655062

LHT:

122500557

LBD:

127281507

MDL:

103578853

CGLO:

123269391

FAS:

105268192

DAM:

107046331

AGIF:

122854346

CINS:

118068073

VCAN:

122408794

CCIN:

107265267

DSM:

124415066

NPT:	124223631 124224681

NFB:	124187143 124187695

NLO:	107221461 107226293

NVG:	124309587 124310121

AROA:

105693251

TCA:

660081

TMOL:

138136598(Ppcs)

DPA:

109535479

ESIM:

136410406(Ppcs)

EFOR:

136346022(Ppcs)

SOY:

115891324

AGRG:

126750291

ATD:

109609696

CSET:

123319160

HAXR:

123688716

AGB:

108916466

LDC:

111502572

DVV:

114333217

NVL:

108556490

DCOR:

135801516(Ppcs)

APLN:

108743595

PPYR:

116163642 116164075

OTU:

111428402

BMOR:

101744316

BMAN:

114239951

MSEX:

115451570 119192357 119192399

DPL:	KGM_210635

BANY:

112047925

MJU:

123868766

NIQ:

126772927

VCD:

124535353

MCIX:

123657986

PMAC:

106711815

PXU:

106117897

BPHI:

137923569(Ppcs)

PRAP:

110992047

PBX:

123708628

PNAP:

125049391

ZCE:

119838778

CCRC:

123694939

LSIN:

126974563

AAGE:

121725255

HAW:	110383582(ppcS)

HZE:

124634269

TNL:

113493400

SLIU:

111355954

OFU:

114353399

ONU:

135077024

ATRA:

106136772

GMW:

113519069

PXY:

105396574

PGW:

126369987

CSTB:

134749026

CFEL:

113377358

CCRN:

123291915

API:

100163022

DNX:

107167285

AGS:

114129052

RMD:

113553848

ACOO:

126841107

DVT:

126905943

BTAB:

109030283

DCI:

103512227

CLEC:

106674302

HHAL:

106690778(Ppcs)

NLU:

111047123

HVI:

124368949

MQU:

128998275

PHU:	Phum_PHUM259630

FOC:	113206610 113217260

ZNE:

110839972

CSEC:

111871309

SGRE:

126293683

BROR:

134535201

IEL:

124171930

HAMR:

139690874(Ppcs)

FCD:

110863257

DPX:	DAPPUDRAFT_45011

DMK:

116926312

DPZ:

124327237

AFRA:

136032305

PVM:

113820687

PJA:

122256060

PCHN:

125045588

PMOO:

119584523

HAME:

121867384

PCLA:

123762714(Ppcs)

CQD:	128693276(Ppcs)

PTRU:

123520495

ESN:

127009714

MNZ:

135196446

MRJ:	136840837(Ppcs)

PORN:

139757667(Ppcs)

HAZT:

108667766

EAF:

111710008

LSM:	121122823(Ppcs)

PPOI:

119113865 119114389

DSV:

119456296

RSAN:

119378203 119393578

RMP:

119171884

VDE:

111243660

VJA:

111268829

TUT:

107366377

DPTE:

113799837

DFR:

124490719

CSCU:

111625717

CVS:	136989084(Ppcs)

PTEP:

107457055

ABRU:

129983973

UDV:	129225652 129233535

SDM:

118195775

LPOL:

106471035

PMEO:

129581273

CEL:	CELE_Y71H2AM.6(Y71H2AM.6)

CBR:

CBG_09817

CRQ:	GCK72_009624

BMY:	BM_BM13973(Bm13973)

LOA:	LOAG_01280

TSP:

Tsp_10032

HRO:	HELRODRAFT_142989

LGI:	LOTGIDRAFT_110784

PVUL:

126831753

PCAN:

112557722

LSAX:

138947224

BGT:

106067959

GAE:

121373726

HRF:

124134668

HRJ:

124288547

HASI:

137297702

HCRA:

139463392

CRG:

105342890

CANU:

128186049

CVN:

111134767

OED:

125645750

MYI:

110451916

PMAX:

117322545

AIRR:

138320589

MCAF:

127727876

MMER:

123561537

RPHI:

132718706 132731859

DPOL:

127859981

MAEA:

128234560

OBI:

106869582

OSN:	115220681 115228358

LJP:

135482335

LAK:	106158648 106158669

SMM:	Smp_131090

OVI:	T265_00160 T265_00164

LLON:

135497894

NVE:	5499071 5516124

EPA:

110238329

ADF:

107338862

PDAM:

113680872

SPIS:

111333219

DGT:

114534012

TAD:	TRIADDRAFT_21703

AQU:

100632677

ATH:	AT1G12350(COAB) AT5G02080

ALY:	9309105 9325992

CRB:

17896814

CSAT:

104708941 104734212 104739885 104755502 104771278

EUS:	EUTSA_v10014147mg

BRP:	103847479 103850438

BNA:	106432532 106433523 106433563

BOE:	106313101 106326761

RSZ:	108834747 108839977

THJ:

104813137

CPAP:

110815197

CIT:

102609359

CIC:	CICLE_v10005436mg

PVY:	116126091 116131539

MINC:

123230153

TCC:

18592236

GRA:

105786143

GHI:	107922382 107925904

GAB:

108460574

HSYR:

120155674 120160913 120198572

DZI:	111299830 111311261 111315600

EGR:

104450967

RARG:

115751409

GMX:	100777777 100808811

GSJ:	114410474 114415359

PVU:

137821746

VRA:

106760923

VAR:

108330018

VUN:

114195895

VUM:

124846063

CCAJ:

109798121

APRC:

113871860

MTR:	11440221 25489392

TPRA:

123896930 123923403

CAM:	101497791 105851170

PSAT:

127073661

VVO:

131604406

LJA:

130734159

ADU:	107460811 107473380

AIP:	107606108 107624942 107630330

AHF:	112706133 112726903 112736967 112738152 112766648

LANG:

109326059 109328582

PCIN:

129317607

QSA:	O6P43_015253 O6P43_019695

FVE:

101302311

AANS:

126794129

RCN:	112180118 112195869 112195879

PPER:

18791206

PMUM:

103332954

PAVI:

110754094

PDUL:

117615804

MDM:	103416203 103421294

MSYL:

126604729 126631837

PXB:	103936128 103942766 103957001

PCOX:

137718399 137747921

ZJU:

107422696

MNT:

21404361

CSAV:

115702238 115715254

CSV:

101214416

CMO:

103488424

BHJ:

120075282

MCHA:

111004651

CMAX:

111496541

CMOS:

111454754

CPEP:

111798026

RCU:

8263001

MEAN:

126666159 126682434

JCU:

105638860

HBR:

110634554

MESC:

110604814

POP:	7463190 7469116

PEU:	105112743 105127879

PALZ:

118029181 118041721

PNZ:

133691222

JRE:	109012450 109021340

CILL:

122309112 122313154

CAVE:

132182469

AGLU:

133854004

QSU:

112023230

QLO:

115972384

TWL:

120010048

VVI:

100264408

VRI:

117906383

SLY:	101254283 101259538

SPEN:

107006035 107017006

SOT:	102588919 102590816

SSTN:

125851482 125863421

SDUL:

129880087 129903327

CANN:

107867573 124889802

LBB:	132603921 132627437

NTA:	107794222 107797793 107799632 107821980

NSY:	104229704 104238619

NTO:	104086248 104107836

NAU:	109216702 109236957

INI:

109151330

ITR:

116018721

SIND:

105165946

OEU:	111396735 111408904

EGT:	105950980 105951009

SSPL:

121765894 121792871

SMIL:

130987852

SHIS:

125201440 125223190

APAN:

127257412

HAN:	110942323 110942448 110942460

ECAD:

122578790

LSV:	111908051 111920701

CCAV:

112511116 112514381

DCR:	108199462 108199557

CSIN:

114260205 114324090

RVL:

131333522

AEW:

130787641

DLT:

127799320

BVG:

104895245

SOE:

110801139

CQI:	110706674 110709720

ATRI:

130810235

MOF:

131161366

NNU:

104589311

MING:

122082922

TSS:

122661913

PSOM:

113331737 113347465

OSA:	4329749(OsJ_07236) 4344795(OsJ_36371)

DOSA:

Os02g0575200 Os08g0176100

OBR:	102705934 102710850

OGL:	127763177 127782852

BDI:	100821221 100835250

ATS:	109761447 109768359

TDC:	119324230 119330438 119339879

TAES:

123134136 123144636 123149575 123159825 123167176

TUA:

125522025

LPER:

127326270 127326448

LRD:	124654334 124654391 124688213 124688748 124690437 124690449

SBI:	8072624 8080899

ZMA:	100193520 100283870

MFLO:

136462366 136463638 136470181 136472076 136472088 136473994

SITA:

101763961 101772064

SVS:	117833591 117859536

PVIR:

120656183 120679321 120706162 120711563

PHAI:

112897670 112900265

PAUA:

133895850 133898467 133919143

PDA:

103715234

EGU:

105060911

MUS:

135617573

ZOF:	121967707 122052950

DCT:

110111014

PEQ:

110031606

AOF:

109832648

MSIN:

131243270

ACAK:

137936705 137937118

NCOL:

116258821

ATR:

18422188

CJF:

131055473

SMO:	SELMODRAFT_172589 SELMODRAFT_417301 SELMODRAFT_57639 SELMODRAFT_96458

PPP:

112288417

CRE:	CHLRE_01g048050v5

MNG:

MNEG_0529

CSL:	COCSUDRAFT_37270

APRO:

F751_5622

OLU:	OSTLU_6578

OTA:	OT_ostta01g00390

BPG:	Bathy01g00300

MIS:	MICPUN_71596

MPP:	MICPUCDRAFT_5184

CME:	CYME_CMQ096C

GSL:	Gasu_28840

SCE:	YIL083C(CAB2)

SPAO:

SPAR_I00840

AGO:	AGOS_AGR391W

ERC:

Ecym_3343

KLA:	KLLA0_E08757g

KMX:	KLMA_80113(CAB2)

LTH:	KLTH0G10846g

VPO:	Kpol_1003p52

ZRO:	ZYRO0A02332g

CGR:	2891688(GVI51_M06677)

NCS:	NCAS_0B06150(NCAS0B06150)

NDI:	NDAI_0B03450(NDAI0B03450)

TPF:	TPHA_0G00840(TPHA0G00840)

TBL:	TBLA_0B06070(TBLA0B06070)

TGB:	HG536_0A02130

TDL:	TDEL_0G02350(TDEL0G02350)

KAF:	KAFR_0H03260(KAFR0H03260)

KNG:	KNAG_0A05310(KNAG0A05310) KNAG_0H01950(KNAG0H01950)

ZMK:	HG535_0D01850

SLUD:

SCDLUD_002734

DHA:	DEHA2A09922g

PIC:	PICST_54534

PGU:	PGUG_02000

SPAA:

SPAPADRAFT_140523

LEL:	PVL30_003629(CAB2)

LBG:	92208592(LODBEIA_P33960)

CAL:	CAALFM_C305760WA(CaO19.7357)

CTP:	CTRG_02452

COT:	CORT_0C02080

CDU:	CD36_85700

CTEN:

18247374(CAB2)

CLU:	CLUG_04761

CLUS:

A9F13_11g00330

CAUR:

CJI96_0002772

ASAU:

88171764(PUMCH_000696)

PPA:	PAS_chr2-2_0204

PKZ:	C5L36_0A10970

BNN:	FOA43_004190

BBRX:

BRETT_001965

OPA:	HPODL_01352

YLI:	2910038(YALI2_C01056g)

NCR:

NCU09090

NTE:	NEUTE1DRAFT70340(NEUTE1DRAFT_70340)

SMP:	10804453(SMAC4_05243)

PAN:	PODANSg4220

PBEL:

QC761_117370(CAB2)

PPSD:

QC762_117370(CAB2)

PPSP:

QC763_117370(CAB2)

PPSA:

QC764_117370(CAB2)

TTT:	THITE_2111714

MTM:	MYCTH_2085895

CTHR:

CTHT_0012610

RTHE:

98122506(VTJ83DRAFT_1677)

MGR:

MGG_17982

PPEI:

PpBr36_09703

PGRI:

PgNI_10677

TMN:	UCRPA7_5693

SSCK:

SPSK_03373

FGR:	FGSG_08803

FPU:	FPSE_11970

FPOA:

FPOAC1_004938

FVN:	FVRRES_05453

FVR:	FVEG_01841

FOX:	FOXG_02990

NHE:	NECHADRAFT_67579

FFC:	NCS54_00422500

FKR:	NCS57_00427800

FMU:	J7337_008207

TRE:	TRIREDRAFT_3350

TRR:	M419DRAFT_76070

TATV:

25783502(TrAtP1_002120)

TASP:

36611575(TrAFT101_000488)

MAW:	19245261(CAB2)

MAJ:

MAA_03810

MBRN:

26245559(CAB2)

PCHM:

VFPPC_04827

AMUS:

LMH87_002099

PLJ:	28882599(PLICBS_001386)

PTKZ:

JDV02_010081(CAB2)

VDA:	VDAG_01811

CFJ:	CFIO01_12807

CLUP:

CLUP02_08840

CHIG:

CH63R_07523

CDET:

87944721(CDEST_08218)

ELA:	UCREL1_8778

PFY:	PFICI_10569

SSL:	SS1G_09394

BFU:	BCIN_06g04980(Bccab2)

MBE:

MBM_07184

PSCO:

LY89DRAFT_589644

GLZ:	GLAREA_11509

ANI:	ANIA_04830

AFM:	AFUA_3G07230

ACT:	ACLA_035170

NFI:	NFIA_070020

AOR:	AO090020000202

ANG:	An02g13510

AFV:	AFLA_010461

ALUC:

AKAW2_11133S

ACHE:

ACHE_70344S

APUU:

APUU_31049S

PCS:	N7525_008666

PDP:	PDIP_09730

POU:	POX_g08867

TMF:	EYB26_008806

TRG:	TRUGW13939_10993

CIM:	CIMG_00337

CPW:	9692103(D8B26_005186)

URE:	UREG_00402

ABE:

ARB_07380

TVE:

TRV_00221

PBL:	PAAG_03857

PBN:	PADG_11590

AJE:	HCAG_07269

BGH:	BDBG_00825

PNO:	SNOG_00223

PTE:

PTT_16312

PTRR:

6345443(PtrM4_042100)

BZE:	COCCADRAFT_82201

BSC:	COCSADRAFT_306199

BOR:	COCMIDRAFT_89442

AALT:

CC77DRAFT_62378

ADAC:

96085124(ACET3X_004802)

ARAB:

EKO05_0004381

ZTR:	MYCGRDRAFT_88465

PFJ:	MYCFIDRAFT_65188

FFU:	CLAFUR5_14063

CBET:

CB0940_05478

BCOM:

BAUCODRAFT_66284

NPA:	UCRNP2_9487

TML:	GSTUM_00009271001

SPO:	2539367(ppc1)

SOM:	SOMG_04559(ppc1)

CNE:

CNE03180

CNB:

CNBE3190

CNG:	CNAG_02222

CGI:	CGB_E4190C

CDEU:

CNBG_5362

CDEP:

91085309(L203_101095)

KMG:	30160388(I203_104482)

KNE:	92180767(IAR55_003509)

TMS:	TREMEDRAFT_44607

TASA:

A1Q1_04608

CCAC:

CcaHIS019_0210330(CAB2)

TVS:	TRAVEDRAFT_39401

DSQ:	DICSQDRAFT_88872

PCO:	PHACADRAFT_116598

SHS:	STEHIDRAFT_75605

HIR:	HETIRDRAFT_67218

PSQ:	PUNSTDRAFT_103147

ADL:	AURDEDRAFT_116159

FME:	FOMMEDRAFT_113269

GTR:	GLOTRDRAFT_80252

RSX:	RhiXN_10502

LBC:	LACBIDRAFT_185029

CCI:	CC1G_07662

ABP:	AGABI1DRAFT115287(AGABI1DRAFT_115287)

ABV:	AGABI2DRAFT194249(AGABI2DRAFT_194249)

PCUB:

JR316_0008795

MRR:	Moror_7689

E1B28_005680

SCM:	SCHCO_02641119(SCHCODRAFT_02641119)

CPUT:

CONPUDRAFT_60642

SLA:	SERLADRAFT_457523

WSE:	WALSEDRAFT_9733

UMA:	UMAG_03699

PFP:	PFL1_04969

SGRA:

EX895_001139

MGL:

MGL_0113

MRT:

MRET_1206

MSYM:

MSY001_0501

PGR:	PGTG_11375 PGTG_11417

PTRC:

PtA15_7A91 PtA15_7A93

PSTR:

Pst134EA_009010 Pst134EA_032977

MLR:	MELLADRAFT_38628

RIE:	OCT59_023026

MBR:	MONBRDRAFT_30065

SRE:	PTSG_08107

DDI:	DDB_G0282611

DPP:	DICPUDRAFT_159223

DFA:

DFA_11657

ACAN:

ACA1_230520

PYO:	PY17X_0616300

PCB:	PCHAS_0615300

PBE:	PBANKA_0613600

PKN:	PKNH_0310500

PVX:	PVX_000630

PCY:	PCYB_031970

PCOT:

PCOAH_00005170

TAN:

TA12810

TOT:	TOT_020000364

BEQ:	BEWA_021100

BBO:	BBOV_III006270

BBIG:

BBBOND_0308500

CPV:

cgd4_2250

CHO:	Chro.40256

TGO:	TGME49_318600

TET:	TTHERM_01309090

PTM:	GSPATT00015070001

FCY:	FRACYDRAFT_162082

TPS:	THAPSDRAFT_15545

AAF:	AURANDRAFT_54169

PIF:	PITG_16385

PSOJ:

PHYSODRAFT_506618

SPAR:

SPRG_05012

TBR:	Tb927.3.1970

TBG:	TbgDal_III1890

TCR:

504045.80

LMA:	LMJF_25_1900

LIF:	LINJ_25_1980

LDO:	LDBPK_251980

LMI:	LMXM_25_1900

LMAT:

92515383(LSCM1_05406)

LBZ:	LBRM_25_1460

LPAN:

LPMP_251980

LOI:	92360466(LSCM4_04548)

LEIS:

94179849(GH5_04412)

LENR:

94172505(CUR178_05302)

LEIN:

94188262(JIQ42_04604)

PHET:

94290752(JKF63_04697)

EHX:	EMIHUDRAFT_229510 EMIHUDRAFT_55007 EMIHUDRAFT_55011

GTT:	GUITHDRAFT_69144

» show all

Reference

1 [PMID:11923312]

Authors

Daugherty M, Polanuyer B, Farrell M, Scholle M, Lykidis A, de Crecy-Lagard V, Osterman A

Title

Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics.

Journal

J Biol Chem 277:21431-9 (2002)
DOI:10.1074/jbc.M201708200

Sequence

[hsa:79717]

Reference

2 [PMID:12906824]

Authors

Manoj N, Strauss E, Begley TP, Ealick SE.

Title

Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution.

Journal

Structure 11:927-36 (2003)
DOI:10.1016/S0969-2126(03)00146-1

Sequence

[hsa:79717]

Reference

3 [PMID:12860978]

Authors

Kupke T, Hernandez-Acosta P, Culianez-Macia FA

Title

4'-phosphopantetheine and coenzyme A biosynthesis in plants.

Journal

J Biol Chem 278:38229-37 (2003)
DOI:10.1074/jbc.M306321200

Sequence

[ath:AT1G12350]

Other DBs

ExplorEnz - The Enzyme Database:

6.3.2.51

IUBMB Enzyme Nomenclature:

6.3.2.51

ExPASy - ENZYME nomenclature database:

6.3.2.51

BRENDA, the Enzyme Database:

6.3.2.51

CAS:

9023-50-1

LinkDB

DBGET integrated database retrieval system