| Entry |
|
|---|
| Name |
Prednisolone acetate (JP18/USP/INN);
Econopred (TN);
Pred forte (TN) |
|---|
| Product |
|
|---|
| Generic |
PREDNISOLONE ACETATE (A-S Medication Solutions), PREDNISOLONE ACETATE (A-S Medication Solutions), PREDNISOLONE ACETATE (A-S Medication Solutions), PREDNISOLONE ACETATE (Asclemed USA), PREDNISOLONE ACETATE (Lupin Pharmaceuticals), PREDNISOLONE ACETATE (NuCare Pharmaceuticals), PREDNISOLONE ACETATE (Pacific Pharma), PREDNISOLONE ACETATE (REMEDYREPACK), PREDNISOLONE ACETATE (RedPharm Drug), PREDNISOLONE ACETATE (RedPharm Drug), PREDNISOLONE ACETATE (Sandoz) |
|---|
| Formula |
C23H30O6
|
|---|
| Exact mass |
402.2042
|
|---|
| Mol weight |
402.48
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 1315 |
| Product (DG00093): | D00472<JP/US> D00980<JP/US> D00981<JP/US> D01239<JP> D03301<JP> |
| Product (mixture): | D11699<US> |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC04 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA01 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA04 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA03 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB06 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA04 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA03 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1315 Ophthalmic cortisones
D00980 Prednisolone acetate (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for urogenital organs and anus
30 Hemorrhoid drugs for external use
D00980 Prednisolone acetate (JP18/USP/INN)
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D00980 Prednisolone acetate (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Prednisolone acetate
D00980 Prednisolone acetate (JP18/USP/INN)
Second-class OTC drugs
Inorganic and organic chemicals
Prednisolone acetate
D00980 Prednisolone acetate (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
D00980 Prednisolone acetate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00980 Prednisolone acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00980 Prednisolone acetate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C2x C 26.7400 -19.3900
2 C5x C 26.7400 -20.7200
3 C2x C 27.9300 -21.4200
4 C2y C 29.1200 -20.7200
5 C1z C 29.1200 -19.3900
6 C2x C 27.9300 -18.6900
7 C1x C 30.3100 -21.4200
8 C1x C 31.5000 -20.7200
9 C1y C 31.5000 -19.3900
10 C1y C 30.3100 -18.6900
11 C1y C 32.6900 -18.6900
12 C1z C 32.6900 -17.2900
13 C1x C 31.5000 -16.5900
14 C1y C 30.3100 -17.2900
15 C1x C 35.0000 -18.6900
16 C1x C 35.0000 -17.2900
17 C1z C 33.8800 -16.5900
18 O5x O 25.6200 -21.4200
19 C1a C 29.1200 -17.9900
20 O1a O 29.1200 -16.5900
21 C1a C 32.6900 -15.9600
22 C5a C 33.8800 -14.9100
23 O1a O 35.0000 -15.9600
24 C1b C 35.0000 -14.2100
25 O5a O 32.6900 -14.2100
26 O7a O 36.1900 -14.9100
27 C7a C 37.3800 -14.2100
28 C1a C 38.5000 -14.9100
29 O6a O 37.3800 -12.8800
BOND 32
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 14 20 1 #Up
24 12 21 1 #Up
25 17 22 1 #Up
26 17 23 1 #Down
27 22 24 1
28 22 25 2
29 24 26 1
30 26 27 1
31 27 28 1
32 27 29 2
|
|---|
