| Entry |
|
|---|
| Name |
Ziftomenib (USAN/INN) |
|---|
| Formula |
C33H42F3N9O2S2
|
|---|
| Exact mass |
717.2855
|
|---|
| Mol weight |
717.88
|
|---|
| Structure |
|
|---|
| Efficacy |
Antineoplastic, Menin-MLL interaction inhibitor |
|---|
| Comment |
Treatment of acute myeloid leukemia
|
|---|
| Target |
|
|---|
| Pathway |
| hsa05202 | Transcriptional misregulation in cancer |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Cellular process
Chromatin
MEN1
D12419 Ziftomenib (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 49
1 C1x C 18.2700 -13.3000
2 N1y N 18.2700 -14.7000
3 C1x C 17.0800 -15.4000
4 C1x C 15.8200 -14.7000
5 C1y C 15.8200 -13.3000
6 C1x C 17.0800 -12.6000
7 C1b C 19.4600 -15.4000
8 C8y C 20.6500 -14.7000
9 C8x C 20.6500 -13.3000
10 C8x C 21.9100 -12.6000
11 C8y C 23.1000 -13.3000
12 C8y C 23.1000 -14.7000
13 C8y C 21.9100 -15.4000
14 C1a C 21.9100 -16.8000
15 N4y N 24.4300 -12.8800
16 C8y C 25.2700 -14.0000
17 C8x C 24.4300 -15.1200
18 C3b C 26.6700 -14.0000
19 N3a N 28.0700 -14.0000
20 C1b C 24.8500 -11.5500
21 C1c C 26.2500 -11.2700
22 C1a C 27.1600 -12.3200
23 N1y N 26.6700 -9.9400
24 C1x C 25.7600 -8.8900
25 C1x C 26.1800 -7.5600
26 N1y N 27.5100 -7.2800
27 C1x C 28.4900 -8.3300
28 C1x C 28.0000 -9.6600
29 S4a S 27.9300 -5.9500
30 C1a C 28.3500 -4.6200
31 O3c O 29.3300 -6.3000
32 O3c O 26.6000 -5.6000
33 N1b N 14.6300 -12.6000
34 C8y C 14.6300 -11.2000
35 C8y C 13.4400 -10.5000
36 C8y C 13.4400 -9.1000
37 N5x N 14.6300 -8.4000
38 C8y C 15.8200 -9.1000
39 N5x N 15.8200 -10.5000
40 N1b N 17.0100 -8.4000
41 C1a C 18.2000 -9.1000
42 C8x C 12.1100 -10.9200
43 C8y C 11.2700 -9.8000
44 S2x S 12.1100 -8.6800
45 C1b C 9.8700 -9.8000
46 C1d C 9.1700 -8.6100
47 X F 10.3600 -7.9100
48 X F 7.9800 -9.3100
49 X F 8.4700 -7.3500
BOND 54
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 2 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 13 14 1
16 11 15 1
17 15 16 1
18 16 17 2
19 12 17 1
20 16 18 1
21 18 19 3
22 15 20 1
23 20 21 1
24 21 22 1 #Up
25 21 23 1
26 23 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 23 28 1
32 26 29 1
33 29 30 1
34 29 31 2
35 29 32 2
36 5 33 1
37 33 34 1
38 34 35 2
39 35 36 1
40 36 37 2
41 37 38 1
42 38 39 2
43 34 39 1
44 38 40 1
45 40 41 1
46 35 42 1
47 42 43 2
48 43 44 1
49 36 44 1
50 43 45 1
51 45 46 1
52 46 47 1
53 46 48 1
54 46 49 1
|
|---|
