KEGG   NETWORK: N01549
Entry
N01549                      Network                                
Name
Branching microtubule nucleation
Definition
gamma-TuRC == Augumin == TPX2+microtubule
  Expanded
(10844+10426+27229+114791+85378+653784+80097+121441) == (55142+79441+54930+23354+54801+55559+93323) == 22974+(7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688)
Class
nt06515 Regulation of kinetochore-microtubule interactions
Type
Reference
Gene
10844  TUBGCP2; tubulin gamma complex associated protein 2
10426  TUBGCP3; tubulin gamma complex associated protein 3
27229  TUBGCP4; tubulin gamma complex associated protein 4
114791  TUBGCP5; tubulin gamma complex associated protein 5
85378  TUBGCP6; tubulin gamma complex associated protein 6
653784  MZT2A; mitotic spindle organizing protein 2A
80097  MZT2B; mitotic spindle organizing protein 2B
121441  NEDD1; NEDD1 gamma-tubulin ring complex targeting factor
55142  HAUS2; HAUS augmin like complex subunit 2
79441  HAUS3; HAUS augmin like complex subunit 3
54930  HAUS4; HAUS augmin like complex subunit 4
23354  HAUS5; HAUS augmin like complex subunit 5
54801  HAUS6; HAUS augmin like complex subunit 6
55559  HAUS7; HAUS augmin like complex subunit 7
93323  HAUS8; HAUS augmin like complex subunit 8
22974  TPX2; TPX2 microtubule nucleation factor
7846  TUBA1A; tubulin alpha 1a
10376  TUBA1B; tubulin alpha 1b
84790  TUBA1C; tubulin alpha 1c
7278  TUBA3C; tubulin alpha 3c
113457  TUBA3D; tubulin alpha 3d
112714  TUBA3E; tubulin alpha 3e
7277  TUBA4A; tubulin alpha 4a
51807  TUBA8; tubulin alpha 8
203068  TUBB; tubulin beta class I
81027  TUBB1; tubulin beta 1 class VI
7280  TUBB2A; tubulin beta 2A class IIa
347733  TUBB2B; tubulin beta 2B class IIb
10381  TUBB3; tubulin beta 3 class III
10382  TUBB4A; tubulin beta 4A class IVa
10383  TUBB4B; tubulin beta 4B class IVb
84617  TUBB6; tubulin beta 6 class V
347688  TUBB8; tubulin beta 8 class VIII
Reference
PMID:33190097
  Authors
Liu P, Wurtz M, Zupa E, Pfeffer S, Schiebel E
  Title
Microtubule nucleation: The waltz between gamma-tubulin ring complex and associated proteins.
  Journal
Curr Opin Cell Biol 68:124-131 (2021)
DOI:10.1016/j.ceb.2020.10.004
Reference
PMID:35385739
  Authors
Almeida AC, Soares-de-Oliveira J, Drpic D, Cheeseman LP, Damas J, Lewin HA, Larkin DM, Aguiar P, Pereira AJ, Maiato H
  Title
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.
  Journal
Cell Rep 39:110610 (2022)
DOI:10.1016/j.celrep.2022.110610
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