Ben Croker

Title(s)Associate Adjunct Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    The Neutrophil Lineage in Inflammasomopathies
    NIH R01AI155869Sep 22, 2020 - Aug 31, 2025
    Role: Principal Investigator
    Defining the roles of RIPK1 and RIPK3 in emergency hematopoiesis
    NIH R01HL124209Dec 1, 2014 - Nov 30, 2020
    Role: Principal Investigator
    NLRP1 activation induces deletion of hematopoietic progenitor cells
    NIH R56AI103352Sep 6, 2013 - Aug 31, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Eosinophilic Esophagitis Drives Tissue Fibroblast Regenerative Programs Towards Pathologic Dysfunction. J Allergy Clin Immunol. 2024 Nov 29. Jumabay M, Abud EM, Okamoto K, Dutta P, Chiang AWT, Li H, Manresa M, Zhu YP, Frederick D, Kurten R, Croker B, Lewis NE, Kennedy JL, Dohil R, Croft M, Ay F, Wechsler JB, Aceves SS. PMID: 39617290.
      View in: PubMed   Mentions:    Fields:    
    2. Turning Neutrophil Cell Death Deadly in the Context of Hypertensive Vascular Disease. Can J Cardiol. 2024 Dec; 40(12):2356-2367. Namin SS, Zhu YP, Croker BA, Tan Z. PMID: 39326672.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells. Cell Rep. 2024 08 27; 43(8):114598. Yu J, Meneses-Salas E, Johnson JL, Manenti S, Kbaich MA, Chen D, Askari K, He J, Shukla A, Shaji B, Gonzalez-Quintial R, Croker BA, Zhang J, Hoffman H, Kiosses WB, Hedrick C, Pestonjamasp K, Wineinger N, Baccala R, Catz SD. PMID: 39126651.
      View in: PubMed   Mentions:    Fields:    
    4. A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. Proc Natl Acad Sci U S A. 2024 Jul 23; 121(30):e2408109121. Leibel SL, McVicar RN, Murad R, Kwong EM, Clark AE, Alvarado A, Grimmig BA, Nuryyev R, Young RE, Lee JC, Peng W, Zhu YP, Griffis E, Nowell CJ, James B, Alarcon S, Malhotra A, Gearing LJ, Hertzog PJ, Galapate CM, Galenkamp KMO, Commisso C, Smith DM, Sun X, Carlin AF, Sidman RL, Croker BA, Snyder EY. PMID: 39028694; PMCID: PMC11287264.
      View in: PubMed   Mentions:    Fields:    
    5. NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis. EMBO Rep. 2024 Jan; 25(1):455. Kaufmann B, Leszczynska A, Reca A, Booshehri LM, Onyuru J, Tan Z, Wree A, Friess H, Hartmann D, Papouchado B, Broderick L, Hoffman HM, Croker BA, Zhu YP, Feldstein AE. PMID: 38216786; PMCID: PMC10897131.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils. Sci Adv. 2023 Dec 22; 9(51):eadj1397. Zhu YP, Speir M, Tan Z, Lee JC, Nowell CJ, Chen AA, Amatullah H, Salinger AJ, Huang CJ, Wu G, Peng W, Askari K, Griffis E, Ghassemian M, Santini J, Gerlic M, Kiosses WB, Catz SD, Hoffman HM, Greco KF, Weller E, Thompson PR, Wong LP, Sadreyev R, Jeffrey KL, Croker BA. PMID: 38117877; PMCID: PMC10732518.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    7. NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice. Nat Commun. 2023 06 26; 14(1):3804. Tran LS, Ying L, D'Costa K, Wray-McCann G, Kerr G, Le L, Allison CC, Ferrand J, Chaudhry H, Emery J, De Paoli A, Colon N, Creed S, Kaparakis-Liaskos M, Como J, Dowling JK, Johanesen PA, Kufer TA, Pedersen JS, Mansell A, Philpott DJ, Elgass KD, Abud HE, Nachbur U, Croker BA, Masters SL, Ferrero RL. PMID: 37365163; PMCID: PMC10293252.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    8. The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense. bioRxiv. 2023 Jan 27. Leibel SL, McVicar RN, Murad R, Kwong EM, Clark AE, Alvarado A, Grimmig BA, Nuryyev R, Young RE, Lee JC, Peng W, Zhu YP, Griffis E, Nowell CJ, Liu K, James B, Alarcon S, Malhotra A, Gearing LJ, Hertzog PJ, Galapate CM, Galenkamp KMO, Commisso C, Smith DM, Sun X, Carlin AF, Croker BA, Snyder EY. PMID: 36747824; PMCID: PMC9900938.
      View in: PubMed   Mentions:
    9. NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis. EMBO Rep. 2022 11 07; 23(11):e54446. Kaufmann B, Leszczynska A, Reca A, Booshehri LM, Onyuru J, Tan Z, Wree A, Friess H, Hartmann D, Papouchado B, Broderick L, Hoffman HM, Croker BA, Zhu YP, Feldstein AE. PMID: 36194627; PMCID: PMC9638850.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    10. Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies. Commun Biol. 2022 08 05; 5(1):789. Li R, Mor M, Ma B, Clark AE, Alter J, Werbner M, Lee JC, Leibel SL, Carlin AF, Dessau M, Gal-Tanamy M, Croker BA, Xiang Y, Freund NT. PMID: 35931732; PMCID: PMC9355996.
      View in: PubMed   Mentions: 3  Translation:HumansCells
    11. Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions. Res Sq. 2022 Mar 17. Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Croker BA, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Clark AE, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. PMID: 35313591; PMCID: PMC8936114.
      View in: PubMed   Mentions:
    12. Non-apoptotic Cell Death Control of Neutrophil Extracellular Trap Formation. Methods Mol Biol. 2022; 2523:253-263. D'Cruz AA, Ericsson M, Croker BA. PMID: 35759202.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    13. Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C. J Clin Invest. 2021 10 15; 131(20). Zhu YP, Shamie I, Lee JC, Nowell CJ, Peng W, Angulo S, Le LN, Liu Y, Miao H, Xiong H, Pena CJ, Moreno E, Griffis E, Labou SG, Franco A, Broderick L, Hoffman HM, Shimizu C, Lewis NE, Kanegaye JT, Tremoulet AH, Burns JC, Croker BA, Pediatric Emergency Medicine Kawasaki Disease Research Group Consortium. PMID: 34464357; PMCID: PMC8516453.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    14. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity. Sci Adv. 2021 08; 7(34). Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. PMID: 34407940; PMCID: PMC8373124.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    15. Walking down the memory lane with SARS-CoV-2 B cells. Immunol Cell Biol. 2021 09; 99(8):796-799. Freund NT, Gerlic M, Croker BA. PMID: 34355822; PMCID: PMC8444909.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    16. Inflammasome Activation in Children With Kawasaki Disease and Multisystem Inflammatory Syndrome. Arterioscler Thromb Vasc Biol. 2021 09; 41(9):2509-2511. Wang WT, He M, Shimizu C, Croker BA, Hoffman HM, Tremoulet AH, Burns JC, Shyy JY. PMID: 34261329; PMCID: PMC8387357.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    17. Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity. PLoS Pathog. 2021 05; 17(5):e1009519. Park SH, Siddiqi H, Castro DV, De Angelis AA, Oom AL, Stoneham CA, Lewinski MK, Clark AE, Croker BA, Carlin AF, Guatelli J, Opella SJ. PMID: 34003853; PMCID: PMC8184013.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    18. The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021 Mar 26. Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. PMID: 33791697; PMCID: PMC8010724.
      View in: PubMed   Mentions: 3  
    19. Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors. PLoS Pathog. 2021 02; 17(2):e1009165. Mor M, Werbner M, Alter J, Safra M, Chomsky E, Lee JC, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Ben-Shalom N, Navon M, Rafael D, Sharim H, Kiner E, Griffis ER, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dessau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. PMID: 33571304; PMCID: PMC7877634.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    20. Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors. bioRxiv. 2020 Oct 06. Mor M, Werbner M, Alter J, Safra M, Chomsky E, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Shalom NB, Navon M, Rafael D, Sharim H, Kiner E, Griffis E, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dassau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. PMID: 33052341; PMCID: PMC7553166.
      View in: PubMed   Mentions:
    21. Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. EMBO J. 2020 11 02; 39(21):e106057. Wang S, Li W, Hui H, Tiwari SK, Zhang Q, Croker BA, Rawlings S, Smith D, Carlin AF, Rana TM. PMID: 32944968; PMCID: PMC7537045.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    22. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity. bioRxiv. 2020 Sep 13. Inde Z, Yapp C, Joshi GN, Spetz J, Fraser C, Deskin B, Ghelfi E, Sodhi C, Hackam DJ, Kobzik L, Croker BA, Brownfield D, Jia H, Sarosiek KA. PMID: 32935109; PMCID: PMC7491524.
      View in: PubMed   Mentions:
    23. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020 04 07; 31(1):107466. Donado CA, Cao AB, Simmons DP, Croker BA, Brennan PJ, Brenner MB. PMID: 32268091; PMCID: PMC7192215.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    24. Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation. Nat Immunol. 2020 01; 21(1):54-64. Speir M, Nowell CJ, Chen AA, O'Donnell JA, Shamie IS, Lakin PR, D'Cruz AA, Braun RO, Babon JJ, Lewis RS, Bliss-Moreau M, Shlomovitz I, Wang S, Cengia LH, Stoica AI, Hakem R, Kelliher MA, O'Reilly LA, Patsiouras H, Lawlor KE, Weller E, Lewis NE, Roberts AW, Gerlic M, Croker BA. PMID: 31819256; PMCID: PMC6923591.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    25. β-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment. PLoS Biol. 2019 09; 17(9):e3000113. Pazhakh V, Ellett F, Croker BA, O'Donnell JA, Pase L, Schulze KE, Greulich RS, Gupta A, Reyes-Aldasoro CC, Andrianopoulos A, Lieschke GJ. PMID: 31483778; PMCID: PMC6746390.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    26. Mutations in topoisomerase IIβ result in a B cell immunodeficiency. Nat Commun. 2019 08 13; 10(1):3644. Broderick L, Yost S, Li D, McGeough MD, Booshehri LM, Guaderrama M, Brydges SD, Kucharova K, Patel NC, Harr M, Hakonarson H, Zackai E, Cowell IG, Austin CA, Hügle B, Gebauer C, Zhang J, Xu X, Wang J, Croker BA, Frazer KA, Putnam CD, Hoffman HM. PMID: 31409799; PMCID: PMC6692411.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    27. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. Cell Stem Cell. 2019 08 01; 25(2):258-272.e9. McKenzie MD, Ghisi M, Oxley EP, Ngo S, Cimmino L, Esnault C, Liu R, Salmon JM, Bell CC, Ahmed N, Erlichster M, Witkowski MT, Liu GJ, Chopin M, Dakic A, Simankowicz E, Pomilio G, Vu T, Krsmanovic P, Su S, Tian L, Baldwin TM, Zalcenstein DA, DiRago L, Wang S, Metcalf D, Johnstone RW, Croker BA, Lancaster GI, Murphy AJ, Naik SH, Nutt SL, Pospisil V, Schroeder T, Wall M, Dawson MA, Wei AH, de Thé H, Ritchie ME, Zuber J, Dickins RA. PMID: 31374198.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    28. Single-cell cloning of human T-cell lines reveals clonal variation in cell death responses to chemotherapeutics. Cancer Genet. 2019 09; 237:69-77. Hanlon K, Thompson A, Pantano L, Hutchinson JN, Al-Obeidi A, Wang S, Bliss-Moreau M, Helble J, Alexe G, Stegmaier K, Bauer DE, Croker BA. PMID: 31447068; PMCID: PMC6711394.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    29. Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling. Osteoarthritis Cartilage. 2019 10; 27(10):1557-1563. Liu X, D'Cruz AA, Hansen J, Croker BA, Lawlor KE, Sims NA, Wicks IP. PMID: 31176017.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. BID-ding on necroptosis in MDS. Blood. 2019 01 10; 133(2):103-104. Croker BA, Kelliher MA. PMID: 30630845; PMCID: PMC6328628.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    31. Necroptosis directly induces the release of full-length biologically active IL-33 in vitro and in an inflammatory disease model. FEBS J. 2019 02; 286(3):507-522. Shlomovitz I, Erlich Z, Speir M, Zargarian S, Baram N, Engler M, Edry-Botzer L, Munitz A, Croker BA, Gerlic M. PMID: 30576068.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    32. The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils. Sci Signal. 2018 09 04; 11(546). D'Cruz AA, Speir M, Bliss-Moreau M, Dietrich S, Wang S, Chen AA, Gavillet M, Al-Obeidi A, Lawlor KE, Vince JE, Kelliher MA, Hakem R, Pasparakis M, Williams DA, Ericsson M, Croker BA. PMID: 30181240; PMCID: PMC6301070.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    33. Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens. Cancer Cell. 2018 06 11; 33(6):1033-1047.e5. Waight JD, Chand D, Dietrich S, Gombos R, Horn T, Gonzalez AM, Manrique M, Swiech L, Morin B, Brittsan C, Tanne A, Akpeng B, Croker BA, Buell JS, Stein R, Savitsky DA, Wilson NS. PMID: 29894690; PMCID: PMC6292441.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    34. Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion. J Immunol. 2018 05 15; 200(10):3341-3346. Chen KW, Lawlor KE, von Pein JB, Boucher D, Gerlic M, Croker BA, Bezbradica JS, Vince JE, Schroder K. PMID: 29661823.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    35. Myelopoiesis embraces its inner weakness. Nat Immunol. 2017 08 22; 18(9):953-954. Gerlic M, Croker BA. PMID: 28829446; PMCID: PMC6289289.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    36. Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia. Oncotarget. 2017 Aug 29; 8(35):57948-57963. McArthur K, D'Cruz AA, Segal D, Lackovic K, Wilks AF, O'Donnell JA, Nowell CJ, Gerlic M, Huang DCS, Burns CJ, Croker BA. PMID: 28938529; PMCID: PMC5601625.
      View in: PubMed   Mentions: 4     Fields:    
    37. Phosphatidylserine externalization, "necroptotic bodies" release, and phagocytosis during necroptosis. PLoS Biol. 2017 Jun; 15(6):e2002711. Zargarian S, Shlomovitz I, Erlich Z, Hourizadeh A, Ofir-Birin Y, Croker BA, Regev-Rudzki N, Edry-Botzer L, Gerlic M. PMID: 28650960; PMCID: PMC5501695.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    38. A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization. Front Cell Infect Microbiol. 2017; 7:219. Hutton ML, D'Costa K, Rossiter AE, Wang L, Turner L, Steer DL, Masters SL, Croker BA, Kaparakis-Liaskos M, Ferrero RL. PMID: 28634572; PMCID: PMC5460342.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    39. A motive for killing: effector functions of regulated lytic cell death. Immunol Cell Biol. 2017 02; 95(2):146-151. Bliss-Moreau M, Chen AA, D'Cruz AA, Croker BA. PMID: 27826146; PMCID: PMC5857356.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    40. IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome. Cell Metab. 2016 Jan 12; 23(1):155-64. Murphy AJ, Kraakman MJ, Kammoun HL, Dragoljevic D, Lee MK, Lawlor KE, Wentworth JM, Vasanthakumar A, Gerlic M, Whitehead LW, DiRago L, Cengia L, Lane RM, Metcalf D, Vince JE, Harrison LC, Kallies A, Kile BT, Croker BA, Febbraio MA, Masters SL. PMID: 26603191.
      View in: PubMed   Mentions: 86     Fields:    Translation:Animals
    41. Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis. Curr Opin Hematol. 2015 Jul; 22(4):293-301. Croker BA, Silke J, Gerlic M. PMID: 26049749; PMCID: PMC4459526.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    42. Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3. Osteoarthritis Cartilage. 2015 Oct; 23(10):1743-54. Liu X, Liu R, Croker BA, Lawlor KE, Smyth GK, Wicks IP. PMID: 26045176.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    43. Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β. J Exp Med. 2015 Jun 01; 212(6):927-38. Kim ML, Chae JJ, Park YH, De Nardo D, Stirzaker RA, Ko HJ, Tye H, Cengia L, DiRago L, Metcalf D, Roberts AW, Kastner DL, Lew AM, Lyras D, Kile BT, Croker BA, Masters SL. PMID: 26008898; PMCID: PMC4451132.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    44. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat Commun. 2015 Feb 18; 6:6282. Lawlor KE, Khan N, Mildenhall A, Gerlic M, Croker BA, D'Cruz AA, Hall C, Kaur Spall S, Anderton H, Masters SL, Rashidi M, Wicks IP, Alexander WS, Mitsuuchi Y, Benetatos CA, Condon SM, Wong WW, Silke J, Vaux DL, Vince JE. PMID: 25693118; PMCID: PMC4346630.
      View in: PubMed   Mentions: 348     Fields:    Translation:AnimalsCells
    45. Fas regulates neutrophil lifespan during viral and bacterial infection. J Leukoc Biol. 2015 Feb; 97(2):321-6. O'Donnell JA, Kennedy CL, Pellegrini M, Nowell CJ, Zhang JG, O'Reilly LA, Cengia L, Dias S, Masters SL, Hartland EL, Roberts AW, Gerlic M, Croker BA. PMID: 25473101.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    46. Key role of suppressor of cytokine signaling 3 in regulating gp130 cytokine-induced signaling and limiting chondrocyte responses during murine inflammatory arthritis. Arthritis Rheumatol. 2014 Sep; 66(9):2391-402. Liu X, Croker BA, Campbell IK, Gauci SJ, Alexander WS, Tonkin BA, Walsh NC, Linossi EM, Nicholson SE, Lawlor KE, Wicks IP. PMID: 24839265.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    47. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell. 2014 May 22; 157(5):1175-88. Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T, Vince JE, Lawlor KE, Ninnis RL, Anderton H, Hall C, Spall SK, Phesse TJ, Abud HE, Cengia LH, Corbin J, Mifsud S, Di Rago L, Metcalf D, Ernst M, Dewson G, Roberts AW, Alexander WS, Murphy JM, Ekert PG, Masters SL, Vaux DL, Croker BA, Gerlic M, Silke J. PMID: 24813849.
      View in: PubMed   Mentions: 315     Fields:    Translation:Animals
    48. NLRP1a expression in Srebp-1a-deficient mice. Cell Metab. 2014 Mar 04; 19(3):345-6. Gerlic M, Croker BA, Cengia LH, Moayeri M, Kile BT, Masters SL. PMID: 24606891.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    49. Neutrophil survival in the death zone. Blood. 2014 Jan 16; 123(3):307-8. Croker BA. PMID: 24434994.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    50. Pyroptotic death storms and cytopenia. Curr Opin Immunol. 2014 Feb; 26:128-37. Croker BA, O'Donnell JA, Gerlic M. PMID: 24556409.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    51. NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells. Immunity. 2012 Dec 14; 37(6):1009-23. Masters SL, Gerlic M, Metcalf D, Preston S, Pellegrini M, O'Donnell JA, McArthur K, Baldwin TM, Chevrier S, Nowell CJ, Cengia LH, Henley KJ, Collinge JE, Kastner DL, Feigenbaum L, Hilton DJ, Alexander WS, Kile BT, Croker BA. PMID: 23219391; PMCID: PMC4275304.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    52. Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor. Cell Death Dis. 2012 Oct 11; 3:e409. Lindqvist LM, Vikström I, Chambers JM, McArthur K, Ann Anderson M, Henley KJ, Happo L, Cluse L, Johnstone RW, Roberts AW, Kile BT, Croker BA, Burns CJ, Rizzacasa MA, Strasser A, Huang DC. PMID: 23059828; PMCID: PMC3481137.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    53. Using feature vectors to detect frog calls in wireless sensor networks. J Acoust Soc Am. 2012 May; 131(5):EL400-5. Croker B, Kottege N. PMID: 22559459.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsPHPublic Health
    54. Towards a four-dimensional view of neutrophils. Methods Mol Biol. 2012; 844:87-99. Croker BA, Roberts AW, Nicola NA. PMID: 22262436.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    55. Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1. Proc Natl Acad Sci U S A. 2011 Aug 09; 108(32):13135-40. Croker BA, O'Donnell JA, Nowell CJ, Metcalf D, Dewson G, Campbell KJ, Rogers KL, Hu Y, Smyth GK, Zhang JG, White M, Lackovic K, Cengia LH, O'Reilly LA, Bouillet P, Cory S, Strasser A, Roberts AW. PMID: 21768356; PMCID: PMC3156212.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    56. IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3. Immunol Cell Biol. 2012 Jan; 90(1):124-9. Croker BA, Kiu H, Pellegrini M, Toe J, Preston S, Metcalf D, O'Donnell JA, Cengia LH, McArthur K, Nicola NA, Alexander WS, Roberts AW. PMID: 21519345; PMCID: PMC3146962.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    57. Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease. J Immunol. 2011 Jan 15; 186(2):1131-9. Croker BA, Lewis RS, Babon JJ, Mintern JD, Jenne DE, Metcalf D, Zhang JG, Cengia LH, O'Donnell JA, Roberts AW. PMID: 21160041.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    58. Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways. J Immunol. 2010 Aug 15; 185(4):2125-33. Zhan Y, Xu Y, Seah S, Brady JL, Carrington EM, Cheers C, Croker BA, Wu L, Villadangos JA, Lew AM. PMID: 20644172.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    59. Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production. EMBO Rep. 2010 Aug; 11(8):640-6. Masters SL, Mielke LA, Cornish AL, Sutton CE, O'Donnell J, Cengia LH, Roberts AW, Wicks IP, Mills KH, Croker BA. PMID: 20596075; PMCID: PMC2920446.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    60. An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nat Immunol. 2010 Apr; 11(4):335-43. Berger M, Krebs P, Crozat K, Li X, Croker BA, Siggs OM, Popkin D, Du X, Lawson BR, Theofilopoulos AN, Xia Y, Khovananth K, Moresco EM, Satoh T, Takeuchi O, Akira S, Beutler B. PMID: 20190759; PMCID: PMC2861894.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    61. A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis. Blood. 2008 Dec 15; 112(13):5193-201. Eyles JL, Hickey MJ, Norman MU, Croker BA, Roberts AW, Drake SF, James WG, Metcalf D, Campbell IK, Wicks IP. PMID: 18824600.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    62. Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):15028-33. Croker BA, Lawson BR, Rutschmann S, Berger M, Eidenschenk C, Blasius AL, Moresco EM, Sovath S, Cengia L, Shultz LD, Theofilopoulos AN, Pettersson S, Beutler BA. PMID: 18806225; PMCID: PMC2567487.
      View in: PubMed   Mentions: 70     Fields:    Translation:Animals
    63. SOCS regulation of the JAK/STAT signalling pathway. Semin Cell Dev Biol. 2008 Aug; 19(4):414-22. Croker BA, Kiu H, Nicholson SE. PMID: 18708154; PMCID: PMC2597703.
      View in: PubMed   Mentions: 265     Fields:    Translation:HumansAnimalsCells
    64. Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation. Exp Hematol. 2008 Jul; 36(7):786-98. Croker BA, Mielke LA, Wormald S, Metcalf D, Kiu H, Alexander WS, Hilton DJ, Roberts AW. PMID: 18400361; PMCID: PMC2556307.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    65. Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16442-7. Alexander WS, Viney EM, Zhang JG, Metcalf D, Kauppi M, Hyland CD, Carpinelli MR, Stevenson W, Croker BA, Hilton AA, Ellis S, Selan C, Nandurkar HH, Goodnow CC, Kile BT, Nicola NA, Roberts AW, Hilton DJ. PMID: 17062753; PMCID: PMC1637601.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    66. SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis. J Clin Invest. 2006 Jun; 116(6):1571-81. Wong PK, Egan PJ, Croker BA, O'Donnell K, Sims NA, Drake S, Kiu H, McManus EJ, Alexander WS, Roberts AW, Wicks IP. PMID: 16710471; PMCID: PMC1462939.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    67. SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. Immunity. 2004 Feb; 20(2):153-65. Croker BA, Metcalf D, Robb L, Wei W, Mifsud S, DiRago L, Cluse LA, Sutherland KD, Hartley L, Williams E, Zhang JG, Hilton DJ, Nicola NA, Alexander WS, Roberts AW. PMID: 14975238.
      View in: PubMed   Mentions: 133     Fields:    Translation:AnimalsCells
    68. SOCS3 negatively regulates IL-6 signaling in vivo. Nat Immunol. 2003 Jun; 4(6):540-5. Croker BA, Krebs DL, Zhang JG, Wormald S, Willson TA, Stanley EG, Robb L, Greenhalgh CJ, Förster I, Clausen BE, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS. PMID: 12754505.
      View in: PubMed   Mentions: 352     Fields:    Translation:AnimalsCells
    69. Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses. Immunol Cell Biol. 2002 Jun; 80(3):231-40. Croker BA, Handman E, Hayball JD, Baldwin TM, Voigt V, Cluse LA, Yang FC, Williams DA, Roberts AW. PMID: 12067410.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    70. The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes. J Immunol. 2002 Apr 01; 168(7):3376-86. Croker BA, Tarlinton DM, Cluse LA, Tuxen AJ, Light A, Yang FC, Williams DA, Roberts AW. PMID: 11907095.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    71. Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4. Gene. 2000 Nov 27; 258(1-2):31-41. Kile BT, Viney EM, Willson TA, Brodnicki TC, Cancilla MR, Herlihy AS, Croker BA, Baca M, Nicola NA, Hilton DJ, Alexander WS. PMID: 11111040.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
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