Local blog

New posts can be found here. There is also a useful tag cloud of subjects, like biology, Europe or GPS/Galileo/GNSS.

Scientific Publications

• Bert Hubert. SkewDB, a comprehensive database of GC and 10 other skews for over 30,000 chromosomes and plasmids. Nature Scientific Data
• Felix Hol, Bert Hubert, Cees Dekker, Juan Keymer. Density-dependent adaptive resistance allows swimming bacteria to colonize an antibiotic gradient. The ISME Journal

DNA related

• On how to average Sanger Q Scores in DNA Sequencing
• DNA seen through the eyes of a coder
• Needleman-Wunsch alignment demo in Javascript
• Antonie - an integrated, robust, reliable and fast processor of DNA reads, mostly from Next Generation Sequencing platforms. It is currently focused on prokaryotic and other small genomes.
• Some notes on how to upload FASTQ to the European Nucleotide Archive
• Hello, and welcome to the wonderful world of DNA sequencing
• DNA: De digitaal van het leven, page 17 of 'De Physicus', October 2014

Food, nutrition, science, health

• Honouring David MacKay's contribution to the future of energy: "being pro-arithmetic" (new!)

Startup, innovation & business related

• How about some actual innovation: Inventing the transistor and landing a nuclear robot on Mars (new!)
• Tin cans, can openers and solar power: explaining the snail’s pace of innovation
• Will your startup idea be successful? I don’t know. But here’s a checklist before you approach people who could help you.
• Being a sophisticated & credible customer, and how to deal with one that isn't
• Interview from book 'De natuurkundige ondernemer' by Kees van den Bos and Witek Nawara (Dutch)

Some random stuff

• HOWTO give a good technical presentation to technical people
• Thoughts on the (non-)utility of DNSSEC
• Explanation of DNSSEC-bis, thoughts on its (non-)utility
• Oldest proof of me on the internet (1992)

Cryptography

• Secrets in Public: Diffie-Hellman key exchange
• On Secure Remote Password, password authenticated key exchange.
• Bitcoins explained for normal people -or- please get back to work

Food

• HOWTO make a decent pizza
• HOWTO make 'Hmmm, lekker' (in dutch)
• Indiaas eten koken (dutch!)

Linux/Unix stuff, programming

• The perfect error message - required reading for programmers
• How to make your DocBook HTML output pretty.
• How to talk to an open source project as a large scale or otherwise interesting user
• Help, my sin() is slow and my FPU is inaccurate
• C++ books I recommend (37000 views so far!)
• PowerDNS.com, my big open source project.
• Some notes on floating point programming with UNIX and Linux
• HOWTO use SIMD (SSE, SSE2, SSE3, 3DNow!, MMX) instructions with gcc.
• Linux 2.4 Advanced Routing & Traffic Shaping HOWTO
• Getting Linux 2.6 to work on a Dell Latitude D800
• Dreambox satellite receiver, some perhaps useful remarks
• Futex manpages I authored (with help from Rusty). Futexes are high performance locking primitives in the 2.6 kernel.
• How to get the linenumber from a linux kernel oops
• Linux Logical Volume Management HOWTO (unmaintained)
• Lex & YACC HOWTO
• Some evil ideas about decentralised loadbalancing/clustering, with no single point of failure
• Beginnings of an rrdtool HOWTO (unfinished, but perhaps useful)
• At one point, I got all fired up about synchronous webservices