CH689805A8 - Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. - Google Patents

Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.

Info

Publication number: CH689805A8
Authority: CH; Switzerland
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; paroxetine methanesulfonate; paroxetine
Prior art date: 1998-07-02

Application number

CH00723/99A

Other languages

English (en)

Other versions

CH689805A5 (fr

Inventor

Neal Ward

David Jones

Andrew Simon Graig

Deirdre O'keeffe

Victor Witold Jacevicz

Michael Urquart

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-02

Filing date

1999-04-20

Publication date

2000-02-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269380&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH689805(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-07-02 Priority claimed from GBGB9814316.7A external-priority patent/GB9814316D0/en

1998-10-06 Priority claimed from GBGB9821732.6A external-priority patent/GB9821732D0/en

1999-02-10 Priority claimed from GBGB9902935.7A external-priority patent/GB9902935D0/en

1999-04-20 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1999-11-30 Publication of CH689805A5 publication Critical patent/CH689805A5/fr

2000-02-29 Publication of CH689805A8 publication Critical patent/CH689805A8/fr

Links

SHIJTGJXUHTGGZ-RVXRQPKJSA-N (3s,4r)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;methanesulfonate Chemical compound CS(O)(=O)=O.C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 SHIJTGJXUHTGGZ-RVXRQPKJSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Inorganic Chemistry (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Psychology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Hematology (AREA)
Addiction (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CH00723/99A 1998-07-02 1999-04-20 Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. CH689805A8 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9814316.7A GB9814316D0 (en)	1998-07-02	1998-07-02	Novel compounds
GBGB9821732.6A GB9821732D0 (en)	1998-10-06	1998-10-06	Novel compound
GBGB9902935.7A GB9902935D0 (en)	1999-02-10	1999-02-10	Novel compound

Publications (2)

Publication Number	Publication Date
CH689805A5 CH689805A5 (fr)	1999-11-30
CH689805A8 true CH689805A8 (fr)	2000-02-29

Family

ID=27269380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH00723/99A CH689805A8 (fr)	1998-07-02	1999-04-20	Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.

Country Status (35)

Country	Link
US (4)	US6063927A (fr)
EP (5)	EP1020464B1 (fr)
JP (1)	JP2002519422A (fr)
KR (1)	KR20010053336A (fr)
CN (1)	CN1127502C (fr)
AR (2)	AR011759A1 (fr)
AT (4)	ATE251155T1 (fr)
AU (4)	AU3619199A (fr)
BE (3)	BE1012403A5 (fr)
BR (1)	BR9911682A (fr)
CA (1)	CA2269999A1 (fr)
CH (1)	CH689805A8 (fr)
DE (5)	DE19918588A1 (fr)
DK (7)	DK199900176U3 (fr)
ES (4)	ES2158778B1 (fr)
FI (2)	FI112077B (fr)
FR (2)	FR2780728B1 (fr)
GB (5)	GB2336364B (fr)
GR (3)	GR990100140A (fr)
HK (1)	HK1037877A1 (fr)
HU (1)	HUP0102334A3 (fr)
IE (5)	IE990344A1 (fr)
IL (1)	IL140628A (fr)
IT (1)	IT1312540B1 (fr)
LU (1)	LU90388B1 (fr)
NL (4)	NL1011875C2 (fr)
NO (1)	NO319030B1 (fr)
NZ (1)	NZ509180A (fr)
PL (1)	PL345214A1 (fr)
PT (4)	PT1089996E (fr)
SE (1)	SE9901462A0 (fr)
SI (3)	SI1020464T1 (fr)
SK (1)	SK20262000A3 (fr)
TR (1)	TR200100054T2 (fr)
WO (1)	WO2000001694A1 (fr)

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JP4081820B2 (ja) *	1997-02-27	2008-04-30	味の素株式会社	晶析装置及び晶析方法
ATE200781T1 (de) *	1997-06-10	2001-05-15	Synthon Bv	4-phenylpiperidin-derivate
CH689805A8 (fr) *	1998-07-02	2000-02-29	Smithkline Beecham Plc	Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
US20040028582A1 (en) *	1999-03-10	2004-02-12	Smithkline Beecham Corporation	Crystallization process for producing fine crystal products
USPP12225P2 (en)	1999-06-01	2001-11-27	Florfis Ag	Geranium plant named ‘Fislamda’
ES2159260B1 (es) *	1999-06-22	2002-05-01	Smithkline Beechan Plc	Nueva composicion de metanosulfonato de paroxetina
WO2000078290A2 (fr) *	1999-06-22	2000-12-28	Smithkline Beecham P.L.C.	Nouvelle preparation
GB0003232D0 (en) *	2000-02-11	2000-04-05	Smithkline Beecham Plc	Novel composition
US6306435B1 (en)	2000-06-26	2001-10-23	Yung Shin Pharmaceutical Industrial Co. Ltd.	Oral pharmaceutical preparation embedded in an oily matrix and methods of making the same
GB0015981D0 (en) *	2000-06-29	2000-08-23	Glaxo Group Ltd	Novel process for preparing crystalline particles
NZ523902A (en) *	2000-08-28	2004-05-28	Synthon Bv	Paroxetine compositions and processes for making the same
DE20100529U1 (de) *	2001-01-11	2001-05-10	Synthon Bv	Pharmazeutische Tablette umfassend Paroxetinmesylat
NL1017421C2 (nl) *	2001-02-21	2002-01-15	Synthon Bv	Werkwijze voor het vervaardigen van paroxetine.
EP1412350A1 (fr) *	2001-08-02	2004-04-28	Spurcourt Limited	Sel d'isethionate de paroxetine, procede de preparation et utilisation dans le traitement de la depression
JP4625637B2 (ja)	2002-02-22	2011-02-02	シャイアエルエルシー	活性物質送達系及び活性物質を保護し投与する方法
US20050266082A1 (en) *	2004-05-26	2005-12-01	Patel Satishkumar A	Preparation of stable paroxetine HC1 ER tablets using a melt granulation process
US20060063737A1 (en) *	2004-08-18	2006-03-23	Holmdahl Lisa K	Liquid paroxetine compositions
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KR100672184B1 (ko)	2004-09-21	2007-01-19	주식회사종근당	파록세틴의 콜린산 또는 콜린산 유도체 염
WO2006110553A2 (fr) *	2005-04-07	2006-10-19	Xy, Inc.	Systeme conditionneur d'une voie d'ecoulement
AU2006315684A1 (en) *	2005-11-14	2007-05-24	Auspex Pharmaceuticals, Inc.	Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties
US8722884B2 (en) *	2005-12-01	2014-05-13	Verastem, Inc.	Pyrimidine derivatives for the treatment of abnormal cell growth
US20080033050A1 (en)	2006-08-04	2008-02-07	Richards Patricia Allison Tewe	Method of treating thermoregulatory disfunction with paroxetine
JP2010520879A (ja) *	2007-03-09	2010-06-17	ノバルティスアーゲー	３−（１ｈ−インドール−３−イル）−４−［２−（４−メチル−ピペラジン−１−イル）−キナゾリン−４−イル］−ピロール−２，５−ジオンの塩
US8119688B2 (en) *	2007-09-19	2012-02-21	Xy, Llc	Differential evaporation potentiated disinfectant system
US20100249166A1 (en) *	2007-09-19	2010-09-30	Xy, Inc.	Differential evaporation potentiated disinfectant system
FR2926552B1 (fr) *	2008-01-23	2010-03-26	Biocodex	Procede de preparation de particules de stiripentol ayant une granulometrie definie
CN103961333B (zh) *	2014-05-07	2020-02-21	浙江华海药业股份有限公司	甲磺酸帕罗西汀胶囊及其制备方法
CN104523645A (zh) *	2014-11-20	2015-04-22	美吉斯制药（厦门）有限公司	甲磺酸帕罗西汀片芯及其包衣片的制备方法
US11111373B2 (en)	2018-12-05	2021-09-07	Chi Mei Corporation	Polymethacrylate composition and optical device made therefrom, and display apparatus

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JP3768536B2 (ja) *	1995-04-03	2006-04-19	アボツト・ラボラトリーズ	低温溶融性薬物と制御放出のための添加物との均質混合物
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GB9514842D0 (en) *	1995-07-20	1995-09-20	Smithkline Beecham Plc	Novel formulation
JP3081250B2 (ja) *	1995-10-31	2000-08-28	メルクエンドカンパニーインコーポレーテッド	置換アゼチジノンの製造方法
IT1276160B1 (it) *	1995-11-22	1997-10-27	Recordati Chem Pharm	Composizioni farmaceutiche orali a pronto rilascio per sospensioni estemporanee
GB9526645D0 (en) *	1995-12-28	1996-02-28	Chiroscience Ltd	Stereoselective synthesis
ES2117557B1 (es) *	1996-02-29	1999-07-01	Ferrer Int	Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina.
JP3446468B2 (ja) *	1996-04-15	2003-09-16	旭硝子株式会社	ピペリジンカルビノール類の製造方法
CA2206592A1 (fr) *	1996-05-30	1997-11-30	Shu-Zhong Wang	Methode de preparation de chlorhydrate de paroxetine amorphe
JP3882224B2 (ja) *	1996-05-31	2007-02-14	旭硝子株式会社	パロキセチンの製造方法
EP1384720A1 (fr) *	1996-06-13	2004-01-28	SUMIKA FINE CHEMICALS Co., Ltd.	Procédé de séchage pour le chlorhydrate de paroxetine
HU221921B1 (hu) *	1996-07-08	2003-02-28	Richter Gedeon Vegyészeti Gyár Rt.	N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
US5672609A (en) *	1996-07-18	1997-09-30	Eli Lilly And Company	Pyridine compounds, intermediates compositions and methods of use
CA2187128A1 (fr) *	1996-10-04	1997-06-26	K. S. Keshava Murthy	Polymorphe nouveau et efficace, a base de chlorhydrate de paroxetine anhydre
ATE200781T1 (de) *	1997-06-10	2001-05-15	Synthon Bv	4-phenylpiperidin-derivate
KR20010040711A (ko) *	1998-02-06	2001-05-15	피터 기딩스	파록세틴의 염
EA200000946A1 (ru) *	1998-03-16	2001-02-26	Смитклайн Бичам Плс	Кристаллическая форма пароксетина
AP2000001950A0 (en) *	1998-04-09	2000-12-31	Smithkline Beecham Plc	Paroxetine maleate.
CH689805A8 (fr) *	1998-07-02	2000-02-29	Smithkline Beecham Plc	Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2159260B1 (es) *	1999-06-22	2002-05-01	Smithkline Beechan Plc	Nueva composicion de metanosulfonato de paroxetina
DE20100529U1 (de) *	2001-01-11	2001-05-10	Synthon Bv	Pharmazeutische Tablette umfassend Paroxetinmesylat

1999
- 1999-04-20 CH CH00723/99A patent/CH689805A8/fr not_active IP Right Cessation
- 1999-04-23 EP EP00201290A patent/EP1020464B1/fr not_active Revoked
- 1999-04-23 ES ES009900849A patent/ES2158778B1/es not_active Expired - Fee Related
- 1999-04-23 DK DK199900176U patent/DK199900176U3/da not_active IP Right Cessation
- 1999-04-23 GR GR990100140A patent/GR990100140A/el not_active IP Right Cessation
- 1999-04-23 AT AT99918159T patent/ATE251155T1/de not_active IP Right Cessation
- 1999-04-23 JP JP2000558097A patent/JP2002519422A/ja active Pending
- 1999-04-23 ES ES99303151T patent/ES2149044T3/es not_active Expired - Lifetime
- 1999-04-23 AU AU36191/99A patent/AU3619199A/en not_active Abandoned
- 1999-04-23 AU AU23928/99A patent/AU732211C/en not_active Ceased
- 1999-04-23 PT PT99918159T patent/PT1089996E/pt unknown
- 1999-04-23 GB GB9909505A patent/GB2336364B/en not_active Revoked
- 1999-04-23 AT AT0027999U patent/AT3185U3/de not_active IP Right Cessation
- 1999-04-23 NZ NZ509180A patent/NZ509180A/en unknown
- 1999-04-23 GB GB0216752A patent/GB2377637A/en not_active Withdrawn
- 1999-04-23 FR FR9905185A patent/FR2780728B1/fr not_active Expired - Fee Related
- 1999-04-23 IE IE19990344A patent/IE990344A1/en not_active IP Right Cessation
- 1999-04-23 ES ES99918159T patent/ES2209428T3/es not_active Expired - Lifetime
- 1999-04-23 EP EP00201289A patent/EP1020463A1/fr not_active Withdrawn
- 1999-04-23 AU AU23937/99A patent/AU713131B3/en not_active Ceased
- 1999-04-23 BR BR9911682-0A patent/BR9911682A/pt not_active Application Discontinuation
- 1999-04-23 IE IE20000894A patent/IES20000894A2/en not_active Application Discontinuation
- 1999-04-23 DK DK99918159T patent/DK1089996T3/da active
- 1999-04-23 GB GB0026487A patent/GB2352395B/en not_active Expired - Fee Related
- 1999-04-23 DK DK199900554A patent/DK199900554A/da not_active Application Discontinuation
- 1999-04-23 WO PCT/GB1999/001253 patent/WO2000001694A1/fr not_active Application Discontinuation
- 1999-04-23 AU AU23938/99A patent/AU713877B3/en not_active Ceased
- 1999-04-23 NL NL1011875A patent/NL1011875C2/nl not_active IP Right Cessation
- 1999-04-23 SI SI9930009T patent/SI1020464T1/xx unknown
- 1999-04-23 PT PT79901275T patent/PT1020464E/pt unknown
- 1999-04-23 EP EP99303151A patent/EP0970955B1/fr not_active Revoked
- 1999-04-23 SK SK2026-2000A patent/SK20262000A3/sk unknown
- 1999-04-23 US US09/299,060 patent/US6063927A/en not_active Expired - Fee Related
- 1999-04-23 CA CA002269999A patent/CA2269999A1/fr not_active Abandoned
- 1999-04-23 DE DE19918588A patent/DE19918588A1/de not_active Ceased
- 1999-04-23 IL IL14062899A patent/IL140628A/en not_active IP Right Cessation
- 1999-04-23 KR KR1020007015099A patent/KR20010053336A/ko not_active Application Discontinuation
- 1999-04-23 BE BE9900293A patent/BE1012403A5/fr not_active IP Right Cessation
- 1999-04-23 BE BE9900294A patent/BE1011664A6/fr not_active IP Right Cessation
- 1999-04-23 IE IE20000893A patent/IES20000893A2/en not_active IP Right Cessation
- 1999-04-23 SI SI9930482T patent/SI1089996T1/xx unknown
- 1999-04-23 FI FI990922A patent/FI112077B/fi active
- 1999-04-23 AT AT99303151T patent/ATE195121T1/de not_active IP Right Cessation
- 1999-04-23 CN CN99810281A patent/CN1127502C/zh not_active Expired - Fee Related
- 1999-04-23 PL PL99345214A patent/PL345214A1/xx not_active Application Discontinuation
- 1999-04-23 GB GB0119695A patent/GB2367003A/en not_active Withdrawn
- 1999-04-23 NO NO19991944A patent/NO319030B1/no unknown
- 1999-04-23 IE IE19990343 patent/IES81166B2/en not_active IP Right Cessation
- 1999-04-23 NL NL1011874A patent/NL1011874C1/nl not_active IP Right Cessation
- 1999-04-23 DE DE69900007T patent/DE69900007T2/de not_active Revoked
- 1999-04-23 EP EP02078483A patent/EP1288214A1/fr not_active Withdrawn
- 1999-04-23 HU HU0102334A patent/HUP0102334A3/hu unknown
- 1999-04-23 DK DK99303151T patent/DK0970955T3/da active
- 1999-04-23 PT PT102291A patent/PT102291B/pt not_active IP Right Cessation
- 1999-04-23 EP EP99918159A patent/EP1089996B1/fr not_active Expired - Lifetime
- 1999-04-23 GB GB9920332A patent/GB2339428A/en not_active Withdrawn
- 1999-04-23 IT IT1999MI000866A patent/IT1312540B1/it active
- 1999-04-23 DE DE69911774T patent/DE69911774T2/de not_active Expired - Fee Related
- 1999-04-23 LU LU90388A patent/LU90388B1/fr active
- 1999-04-23 IE IE20000633A patent/IE20000633A1/en not_active IP Right Cessation
- 1999-04-23 SE SE9901462A patent/SE9901462A0/sv not_active Application Discontinuation
- 1999-04-23 FI FI990190U patent/FI4209U1/fi not_active IP Right Cessation
- 1999-04-23 AR ARP990101885A patent/AR011759A1/es not_active Application Discontinuation
- 1999-04-23 PT PT99303151T patent/PT970955E/pt unknown
- 1999-04-23 DE DE29907248U patent/DE29907248U1/de not_active Expired - Lifetime
- 1999-04-23 SI SI9930002T patent/SI0970955T1/xx unknown
- 1999-04-23 TR TR2001/00054T patent/TR200100054T2/xx unknown
- 1999-04-26 AR ARP990101908A patent/AR018197A1/es unknown
- 1999-06-08 NL NL1012272A patent/NL1012272C1/nl not_active IP Right Cessation
- 1999-06-08 NL NL1012271A patent/NL1012271C2/nl not_active IP Right Cessation
- 1999-06-15 DK DK199900234U patent/DK199900234U4/da not_active IP Right Cessation
- 1999-12-23 BE BE9900832A patent/BE1012420A6/fr not_active IP Right Cessation
2000
- 2000-04-10 DE DE60000003T patent/DE60000003T2/de not_active Revoked
- 2000-04-10 AT AT00201290T patent/ATE202777T1/de not_active IP Right Cessation
- 2000-04-10 ES ES00201290T patent/ES2157881T3/es not_active Expired - Lifetime
- 2000-04-10 DK DK00201290T patent/DK1020464T3/da active
- 2000-09-05 GR GR20000402015T patent/GR3034328T3/el not_active IP Right Cessation
- 2000-11-08 FR FR0014325A patent/FR2802098A1/fr active Pending
- 2000-12-27 DK DK200000390U patent/DK200000390U1/da not_active IP Right Cessation
2001
- 2001-03-14 US US09/805,812 patent/US20010023253A1/en not_active Abandoned
- 2001-07-11 GR GR20010401061T patent/GR3036208T3/el not_active IP Right Cessation
- 2001-09-21 US US09/960,033 patent/US20020035130A1/en not_active Abandoned
- 2001-10-11 HK HK01107165A patent/HK1037877A1/xx not_active IP Right Cessation
2002
- 2002-06-18 US US10/174,380 patent/US20020193406A1/en not_active Abandoned

Also Published As

Publication number	Publication date
GB9909505D0 (en)	1999-06-23
DE69911774D1 (de)	2003-11-06
AR011759A1 (es)	2000-09-13
DE60000003T2 (de)	2002-03-21
BR9911682A (pt)	2001-12-26
GR3034328T3 (en)	2000-12-29
GB9920332D0 (en)	1999-11-03
US20010023253A1 (en)	2001-09-20
GB0026487D0 (en)	2000-12-13
SI0970955T1 (en)	2001-02-28
IL140628A0 (en)	2002-02-10
SE9901462L (fr)
DK199900554A (da)	2000-01-03
NL1012272C1 (nl)	1999-07-12
CA2269999A1 (fr)	2000-01-02
EP1020464A1 (fr)	2000-07-19
GR990100140A (el)	2000-03-31
GB2352395B (en)	2004-02-11
NO991944L (no)	2000-01-03
PT970955E (pt)	2000-11-30
ATE251155T1 (de)	2003-10-15
IES20000894A2 (en)	2001-05-30
SE9901462A0 (sv)	2000-01-03
SI1020464T1 (en)	2001-12-31
ES2157881T3 (es)	2001-09-01
CN1315949A (zh)	2001-10-03
PT102291A (pt)	2000-05-31
FI990922A (fi)	2000-01-03
DE29907248U1 (de)	1999-09-09
GB0119695D0 (en)	2001-10-03
GB0216752D0 (en)	2002-08-28
US6063927A (en)	2000-05-16
IL140628A (en)	2004-06-20
ES2149044T3 (es)	2000-10-16
KR20010053336A (ko)	2001-06-25
FR2780728A1 (fr)	2000-01-07
AU2392899A (en)	2000-01-20
DK1089996T3 (da)	2004-02-09
LU90388B1 (fr)	2001-01-29
NL1011875A1 (nl)	2000-01-07
IE20000633A1 (en)	2001-10-17
DK199900234U4 (da)	2000-12-22
GB2367003A (en)	2002-03-27
NL1012271A1 (nl)	1999-07-12
PT1089996E (pt)	2004-02-27
EP1089996A1 (fr)	2001-04-11
DE19918588A1 (de)	2000-01-27
IES20000893A2 (en)	2001-05-30
HK1037877A1 (en)	2002-02-22
HUP0102334A2 (hu)	2002-05-29
AU713877B3 (en)	1999-12-09
EP1020464B1 (fr)	2001-07-04
NO319030B1 (no)	2005-06-06
FI112077B (fi)	2003-10-31
ITMI990866A1 (it)	2000-10-23
IES81166B2 (en)	2000-05-31
PT1020464E (pt)	2001-10-30
ES2158778B1 (es)	2002-03-16
GB2336364A (en)	1999-10-20
FI990922A0 (fi)	1999-04-23
GB2377637A (en)	2003-01-22
SK20262000A3 (sk)	2001-07-10
FR2802098A1 (fr)	2001-06-15
NL1012271C2 (nl)	1999-09-23
ATE202777T1 (de)	2001-07-15
AU3619199A (en)	2000-01-24
GR3036208T3 (en)	2001-10-31
DK199900234U1 (da)	2000-12-22
TR200100054T2 (tr)	2001-06-21
DK199900176U3 (da)	1999-08-13
IES990343A2 (en)	2000-01-02
SE9901462D0 (sv)	1999-04-23
EP1288214A1 (fr)	2003-03-05
AU732211C (en)	2004-05-06
NL1011874C1 (nl)	1999-07-12
ES2158778A1 (es)	2001-09-01
BE1012420A6 (fr)	2000-10-03
GB2336364B (en)	2000-05-10
DK1020464T3 (da)	2001-09-24
JP2002519422A (ja)	2002-07-02
DK200000390U1 (da)	2000-12-27
AU713131B3 (en)	1999-11-25
EP0970955B1 (fr)	2000-08-02
DE60000003D1 (de)	2001-08-09
DE69900007T2 (de)	2001-06-07
FI4209U1 (fi)	1999-11-10
BE1011664A6 (fr)	1999-11-09
EP1020463A1 (fr)	2000-07-19
AR018197A1 (es)	2001-10-31
EP1089996B1 (fr)	2003-10-01
ES2209428T3 (es)	2004-06-16
US20020035130A1 (en)	2002-03-21
IE990344A1 (en)	2000-05-03
NO991944D0 (no)	1999-04-23
AU732211B2 (en)	2001-04-12
DE69911774T2 (de)	2004-08-05
FIU990190U0 (fi)	1999-04-23
NZ509180A (en)	2001-06-29
BE1012403A5 (fr)	2000-10-03
AT3185U3 (de)	2000-01-25
CN1127502C (zh)	2003-11-12
GB2352395A (en)	2001-01-31
IT1312540B1 (it)	2002-04-22
EP0970955A1 (fr)	2000-01-12
WO2000001694A1 (fr)	2000-01-13
US20020193406A1 (en)	2002-12-19
NL1011875C2 (nl)	2000-03-24
AT3185U2 (de)	1999-11-25
CH689805A5 (fr)	1999-11-30
SI1089996T1 (en)	2004-04-30
FR2780728B1 (fr)	2001-02-16
PL345214A1 (en)	2001-12-03
GR1003350B (el)	2000-03-29
ATE195121T1 (de)	2000-08-15
DE69900007D1 (de)	2000-09-07
PT102291B (pt)	2002-07-31
GB2339428A (en)	2000-01-26
HUP0102334A3 (en)	2003-12-29
DK0970955T3 (da)	2000-10-09

Legal Events

Date	Code	Title	Description
2000-02-15	PK	Correction	Free format text: RECTIFICATION DU FASCICULE DU BREVET
2007-10-30	PFA	Name/firm changed	Owner name: SMITHKLINE BEECHAM P.L.C. Free format text: SMITHKLINE BEECHAM P.L.C.#NEW HORIZONS COURT#BRENTFORD (MIDDX TW8 9EP) (GB) -TRANSFER TO- SMITHKLINE BEECHAM P.L.C.#NEW HORIZONS COURT#BRENTFORD (MIDDX TW8 9EP) (GB)
2009-11-30	PL	Patent ceased
2024-10-31	PK	Correction	Free format text: RECTIFICATION B9

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