HU213570B - Method for the fermentative production of cephalosporin-c - Google Patents
Method for the fermentative production of cephalosporin-c Download PDFInfo
- Publication number
- HU213570B HU213570B HU9400463A HU9400463A HU213570B HU 213570 B HU213570 B HU 213570B HU 9400463 A HU9400463 A HU 9400463A HU 9400463 A HU9400463 A HU 9400463A HU 213570 B HU213570 B HU 213570B
- Authority
- HU
- Hungary
- Prior art keywords
- fermentation
- cephalosporin
- filtrate
- fermenter
- cpc
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/06—Cephalosporin C; Derivatives thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Soy Sauces And Products Related Thereto (AREA)
Claims (6)
- SZABADALMI IGÉNYPONTOK1. Eljárás cefalosporin C fermentációs előállításárára Acremonium chrysogenum törzs felhasználásával, azzal jellemezve, hogy a fermentálás során a fermentációs oldatot átáramlásos szűrőrendszeren szűrjük, ahol a szűrő pórusmérete 4 és 200 nm közötti, és a fermentáló berendezésben a szűrlet mennyiségét pótoljuk.
- 2. Az 1. igénypont szerinti eljárás, azzal jellemezve, hogy polimer vagy kerámia szűrőt alkalmazunk átáramlásos szűrőrendszerként.
- 3. A 1. vagy 2. igénypont szerinti eljárás, azzal jellemezve, hogy a szürőfelületen az átáramlási sebesség 1 és 10 m/s közötti.
- 4. Az 1-3. igénypontok bármelyike szerinti eljárás, azzal jellemezve, hogy a fermentáló berendezésben a szűrletet vízzel pótoljuk.
- 5. A 4. igénypont szerinti eljárás, azzal jellemezve, hogy a szürletet tápoldattal pótoljuk.
- 6. A 4. igénypont szerinti eljárás, azzal jellemezve, hogy a szűrletet a kívánt termék eltávolítása után a fermentáló berendezésbe visszavezetjük.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4127648A DE4127648C1 (hu) | 1991-08-21 | 1991-08-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9400463D0 HU9400463D0 (en) | 1994-06-28 |
| HUT69767A HUT69767A (en) | 1995-09-28 |
| HU213570B true HU213570B (en) | 1997-08-28 |
Family
ID=6438749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9400463A HU213570B (en) | 1991-08-21 | 1992-08-08 | Method for the fermentative production of cephalosporin-c |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0599891B1 (hu) |
| JP (1) | JPH07501207A (hu) |
| CN (1) | CN1045008C (hu) |
| AT (1) | ATE130038T1 (hu) |
| AU (1) | AU663519B2 (hu) |
| CA (1) | CA2116019A1 (hu) |
| CZ (1) | CZ281698B6 (hu) |
| DE (2) | DE4127648C1 (hu) |
| DK (1) | DK0599891T3 (hu) |
| ES (1) | ES2079882T3 (hu) |
| FI (1) | FI103988B (hu) |
| HU (1) | HU213570B (hu) |
| NO (1) | NO940565L (hu) |
| PT (1) | PT100796B (hu) |
| RU (1) | RU2094463C1 (hu) |
| SK (1) | SK279794B6 (hu) |
| TW (1) | TW317572B (hu) |
| WO (1) | WO1993004188A1 (hu) |
| ZA (1) | ZA926271B (hu) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100446110B1 (ko) * | 1997-10-24 | 2004-10-28 | 씨제이 주식회사 | 세팔로스포린 c 생산 미생물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57106683A (en) * | 1980-12-24 | 1982-07-02 | Takeda Chem Ind Ltd | Method for concentrating beta-lactam antibiotic substance |
| DE3307095A1 (de) * | 1983-03-01 | 1984-09-06 | Degussa Ag, 6000 Frankfurt | Mikrobiologisch hergestellte l-phenylalanin-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung |
| CS244333B1 (en) * | 1984-11-02 | 1986-07-17 | Jan Rakyta | Method of c-cephalosporine fermentation production with utilization of fats as limitating carbonaceous substrate by means of acromonium chrysogenum strain |
-
1991
- 1991-08-21 DE DE4127648A patent/DE4127648C1/de not_active Expired - Fee Related
-
1992
- 1992-08-08 WO PCT/EP1992/001811 patent/WO1993004188A1/de active IP Right Grant
- 1992-08-08 CA CA002116019A patent/CA2116019A1/en not_active Abandoned
- 1992-08-08 EP EP92916796A patent/EP0599891B1/de not_active Expired - Lifetime
- 1992-08-08 RU RU9294015848A patent/RU2094463C1/ru active
- 1992-08-08 CZ CZ94366A patent/CZ281698B6/cs not_active IP Right Cessation
- 1992-08-08 AU AU24024/92A patent/AU663519B2/en not_active Ceased
- 1992-08-08 ES ES92916796T patent/ES2079882T3/es not_active Expired - Lifetime
- 1992-08-08 HU HU9400463A patent/HU213570B/hu not_active IP Right Cessation
- 1992-08-08 AT AT92916796T patent/ATE130038T1/de not_active IP Right Cessation
- 1992-08-08 SK SK197-94A patent/SK279794B6/sk unknown
- 1992-08-08 JP JP5504067A patent/JPH07501207A/ja not_active Withdrawn
- 1992-08-08 DK DK92916796.3T patent/DK0599891T3/da active
- 1992-08-08 DE DE59204277T patent/DE59204277D1/de not_active Expired - Fee Related
- 1992-08-20 ZA ZA926271A patent/ZA926271B/xx unknown
- 1992-08-20 PT PT100796A patent/PT100796B/pt not_active IP Right Cessation
- 1992-08-21 CN CN92110651A patent/CN1045008C/zh not_active Expired - Fee Related
- 1992-08-22 TW TW081106636A patent/TW317572B/zh active
-
1994
- 1994-02-18 NO NO940565A patent/NO940565L/no not_active Application Discontinuation
- 1994-02-18 FI FI940778A patent/FI103988B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| FI103988B1 (fi) | 1999-10-29 |
| AU2402492A (en) | 1993-03-16 |
| HUT69767A (en) | 1995-09-28 |
| ATE130038T1 (de) | 1995-11-15 |
| JPH07501207A (ja) | 1995-02-09 |
| RU2094463C1 (ru) | 1997-10-27 |
| ZA926271B (en) | 1993-04-28 |
| CN1071953A (zh) | 1993-05-12 |
| SK279794B6 (sk) | 1999-03-12 |
| NO940565D0 (no) | 1994-02-18 |
| DE4127648C1 (hu) | 1993-01-14 |
| FI103988B (fi) | 1999-10-29 |
| CZ281698B6 (cs) | 1996-12-11 |
| AU663519B2 (en) | 1995-10-12 |
| WO1993004188A1 (de) | 1993-03-04 |
| EP0599891A1 (de) | 1994-06-08 |
| HU9400463D0 (en) | 1994-06-28 |
| FI940778A (fi) | 1994-03-16 |
| EP0599891B1 (de) | 1995-11-08 |
| PT100796B (pt) | 1999-07-30 |
| DK0599891T3 (da) | 1996-02-26 |
| TW317572B (hu) | 1997-10-11 |
| CA2116019A1 (en) | 1993-03-04 |
| PT100796A (pt) | 1993-09-30 |
| CZ36694A3 (en) | 1994-07-13 |
| FI940778A0 (fi) | 1994-02-18 |
| CN1045008C (zh) | 1999-09-08 |
| SK19794A3 (en) | 1994-08-10 |
| ES2079882T3 (es) | 1996-01-16 |
| DE59204277D1 (de) | 1995-12-14 |
| NO940565L (no) | 1994-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HPC4 | Succession in title of patentee |
Owner name: BIOCHEMIE GESELLSCHAFT M.B.H., AT |
|
| HMM4 | Cancellation of final prot. due to non-payment of fee |
