AT350068B - Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen - Google Patents

Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen

Info

Publication number
AT350068B
AT350068B AT28178A AT28178A AT350068B AT 350068 B AT350068 B AT 350068B AT 28178 A AT28178 A AT 28178A AT 28178 A AT28178 A AT 28178A AT 350068 B AT350068 B AT 350068B
Authority
AT
Austria
Prior art keywords
acetide
butter
methylene
derivatives
salt
Prior art date
Application number
AT28178A
Other languages
English (en)
Other versions
ATA28178A (de
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ATA28178A publication Critical patent/ATA28178A/de
Application granted granted Critical
Publication of AT350068B publication Critical patent/AT350068B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02—Sulfinic acids; Derivatives thereof
    • C07C313/04—Sulfinic acids; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT28178A 1974-02-26 1978-01-16 Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen AT350068B (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH1100074 1974-08-12
AT108275A AT337362B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten

Publications (2)

Publication Number Publication Date
ATA28178A ATA28178A (de) 1978-10-15
AT350068B true AT350068B (de) 1979-05-10

Family

ID=27173851

Family Applications (2)

Application Number Title Priority Date Filing Date
AT108275A AT337362B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten
AT28178A AT350068B (de) 1974-02-26 1978-01-16 Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT108275A AT337362B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten

Country Status (21)

Country Link
JP (1) JPS625919B2 (de)
AR (1) AR208538A1 (de)
AT (2) AT337362B (de)
AU (1) AU498131B2 (de)
BE (1) BE825919A (de)
BG (1) BG26201A3 (de)
CA (2) CA1059988A (de)
DD (1) DD117074A5 (de)
DE (1) DE2506330A1 (de)
DK (2) DK73475A (de)
ES (2) ES435110A1 (de)
FI (1) FI66389C (de)
FR (1) FR2261761B1 (de)
GB (1) GB1503581A (de)
HU (1) HU175212B (de)
IE (1) IE40695B1 (de)
IL (1) IL46699A (de)
NL (1) NL7502292A (de)
NO (1) NO750625L (de)
NZ (1) NZ176623A (de)
SE (3) SE431652B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044247B (it) * 1974-08-02 1980-03-20 Farmaceutici Italia Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
JPS5198265A (de) * 1975-02-17 1976-08-30
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPH0639474B2 (ja) * 1983-03-04 1994-05-25 大塚化学株式会社 セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井　康博 薬液収納兼即効注出器
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 ３−ヒドロキシセフェム誘導体の製造法
WO2004039813A1 (en) * 2002-11-01 2004-05-13 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of chloro methyl cephem derivatives
PL2794628T3 (pl) 2011-12-20 2017-09-29 Riboscience Llc 4'-azydo-3'-fluoro podstawione pochodne nukleozydów jako inhibitory replikacji RNA HCV
AU2012357940B2 (en) 2011-12-20 2017-02-16 Riboscience Llc 2',4'-difluoro-2'-methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication
MA38678A1 (fr) 2013-05-16 2017-07-31 Riboscience Llc Dérivés nucléosidiques 4'-azido, 3'désoxy-3'-fluoro substitués
MA46490A1 (fr) 2013-05-16 2021-04-30 Riboscience Llc Dérivés de nucléosides 4'- fluoro-2' - méthyle substitués
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
TWI860279B (zh) 2017-09-21 2024-11-01 美商里伯賽恩斯有限責任公司 作為hcv rna複製抑制劑之經4'-氟-2'-甲基取代之核苷衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat

Also Published As

Publication number Publication date
HU175212B (hu) 1980-06-28
FI66389B (fi) 1984-06-29
DK73475A (de) 1975-10-20
BE825919A (fr) 1975-08-25
FR2261761B1 (de) 1978-08-18
NL7502292A (nl) 1975-08-28
SE7807811L (sv) 1978-07-13
FI750503A (de) 1975-08-27
FR2261761A1 (de) 1975-09-19
NZ176623A (en) 1978-04-03
IE40695B1 (en) 1979-08-01
CA1059988A (en) 1979-08-07
CA1080713A (en) 1980-07-01
AU498131B2 (en) 1979-02-15
DE2506330A1 (de) 1975-09-04
JPS50129590A (de) 1975-10-13
GB1503581A (en) 1978-03-15
AT337362B (de) 1977-06-27
DD117074A5 (de) 1975-12-20
IL46699A (en) 1977-11-30
IL46699A0 (en) 1975-04-25
BG26201A3 (bg) 1979-02-15
DK348678A (da) 1978-08-07
AU7849875A (en) 1976-08-26
IE40695L (en) 1975-08-26
SE438855B (sv) 1985-05-13
SE7807810L (sv) 1978-07-13
SE438854B (sv) 1985-05-13
SE431652B (sv) 1984-02-20
FI66389C (fi) 1984-10-10
ES435110A1 (es) 1977-03-16
ES452915A1 (es) 1977-11-01
SE7501317L (de) 1975-08-27
JPS625919B2 (de) 1987-02-07
AR208538A1 (es) 1977-02-15
ATA28178A (de) 1978-10-15
NO750625L (de) 1975-08-27
ATA108275A (de) 1976-10-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee